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Results for “Chronic Myeloid Leukemia With T315I Mutation”

21 trials

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Showing 20 of 21 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04233346
What this trial is testing

The Study for CML Who Failed Prior TKIs or With T315I Mutation or Ph+ ALL Who Failed Prior TKIs or With T315I Mutation

Who this might be right for
Chronic Myeloid LeukemiaAcute Lymphoblastic Leukemia
Otsuka Beijing Research Institute 93
Large-scale testing (Phase 3)Study completedNCT04666259
What this trial is testing

Asciminib in Monotherapy for Chronic Myeloid Leukemia in Chronic Phase (CML-CP) With and Without T315I Mutation

Who this might be right for
Chronic Myelogenous Leukemia - Chronic Phase
Novartis Pharmaceuticals 56
Testing effectiveness (Phase 2)Study completedNCT01207440
What this trial is testing

Ponatinib for Chronic Myeloid Leukemia (CML) Evaluation and Ph+ Acute Lymphoblastic Leukemia (ALL)

Who this might be right for
Chronic Myeloid LeukemiaPh+ Acute Lymphoblastic Leukemia
Ariad Pharmaceuticals 449
Testing effectiveness (Phase 2)UnknownNCT03883087
What this trial is testing

A Pivotal Study of HQP1351 in Patients of Chronic Myeloid Leukemia in Chronic Phase With T315I Mutation

Who this might be right for
Chronic Myeloid Leukemia, Chronic Phase
Ascentage Pharma Group Inc. 41
Testing effectiveness (Phase 2)Study completedNCT00375219
What this trial is testing

Homoharringtonine (Omacetaxine Mepesuccinate) in Treating Patients With Chronic Myeloid Leukemia (CML) With the T315I BCR-ABL Gene Mutation

Who this might be right for
Chronic Myeloid Leukemia
Teva Branded Pharmaceutical Products R&D, Inc. 103
Not applicableStudy completedNCT05619978
What this trial is testing

French Study to Highlight the Unmet Treatment Needs of 3L+ CP-CML and With T315I-mutated CML Patients

Who this might be right for
Chronic Myeloid Leukemia
Novartis Pharmaceuticals 200
Testing effectiveness (Phase 2)UnknownNCT02885766
What this trial is testing

Study to Evaluate Tolerability, Safety, Pharmacokinetics and Preliminary Efficacy of PF-114 for Oral Administration in Adults With Ph+ Chronic Myeloid Leukemia, Which is Resistant to the 2-nd Generation Bcr-Abl Inhibitors or Has T315I Mutation in the BCR-ABL Gene

Who this might be right for
Chronic Myeloid LeukemiaLeukemia, Myelogenous, Chronic, BCR-ABL Positive
Fusion Pharma LLC 65
Testing effectiveness (Phase 2)Active Not RecruitingNCT05384587
What this trial is testing

Asciminib Monotherapy, With Dose Escalation, for 2nd and 1st Line Chronic Myelogenous Leukemia

Who this might be right for
Chronic Myelogenous Leukemia - Chronic Phase
Novartis Pharmaceuticals 34
Early research (Phase 1)Looking for participantsNCT04260022
What this trial is testing

Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL

Who this might be right for
Leukemia, Myeloid, ChronicMyeloid LeukemiaChronic Myeloid Leukemia+2 more
Ascentage Pharma Group Inc. 242
Not applicableStudy completedNCT05611216
What this trial is testing

Clinical Outcomes of 3L+ Therapies Among Patients With Chronic Myeloid Leukemia and Those With T315I Mutation

Who this might be right for
Chronic Myeloid Leukemia
Novartis Pharmaceuticals 164
Testing effectiveness (Phase 2)UnknownNCT03883100
What this trial is testing

A Pivotal Study of HQP1351 in Patients of Chronic Myeloid Leukemia in Accelerated Phase With T315I Mutation

Who this might be right for
Chronic Myeloid Leukemia - Accelerated Phase
Ascentage Pharma Group Inc. 23
Early research (Phase 1)Looking for participantsNCT06787144
What this trial is testing

ELVN-001 for the Treatment of Chronic Myeloid Leukemia With and Without T315I Mutation in Japanese Participants

Who this might be right for
CML (Chronic Myelogenous Leukemia)Chronic Phase CML
Enliven Therapeutics 21
Testing effectiveness (Phase 2)Looking for participantsNCT07354074
What this trial is testing

Study to Determine the Efficacy and Safety of Asciminib in Pediatric Patients With Ph+ CML-CP

Who this might be right for
Chronic Myelogenous LeukemiaLeukemia, Myelogenous, Chronic, Philadelphia Chromosome Positive
Novartis Pharmaceuticals 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT07789574
What this trial is testing

Efficacy of Asciminib in Chronic Phase CML Patients With T315I Mutations

Who this might be right for
Chronic Myeloid Leukemia (CML)
Thomas Ernst, PD Dr. med. 50
Testing effectiveness (Phase 2)Looking for participantsNCT06514534
What this trial is testing

Open-label Study of Asciminib for CML-CP or CML-AP Patients With T315I Mutation Who Are Resistant, Intolerant or Ineligible to Ponatinib.

Who this might be right for
Chronic Myeloid Leukemia (CML)
Novartis Pharmaceuticals 20
Early research (Phase 1)Study completedNCT00827138
What this trial is testing

Study Safety and Preliminary Efficacy of DCC-2036 in Patients With Leukemias (Ph+ CML With T315I Mutation)

Who this might be right for
Chronic Myeloid Leukemia
Deciphera Pharmaceuticals, LLC 57
Post-approval studies (Phase 4)Study completedNCT06427811
What this trial is testing

Clinical Study of Asciminib in Previously Treated Indian Patients With Ph+ CML-CP Without T315I Mutation and in Patients With Ph+ CML-CP With T315I Mutation

Who this might be right for
Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase
Novartis Pharmaceuticals 85
Testing effectiveness (Phase 2)Ended earlyNCT00405054
What this trial is testing

A Phase II Study of MK0457 in Patients With T315I Mutant CML and Ph+All (0457-008)

Who this might be right for
Leukemia
Merck Sharp & Dohme LLC 52
Not applicableStudy completedNCT02981784
What this trial is testing

Comparative Evaluation of Results of Allogeneic Hematopoietic Stem Cells Versus Ponatinib in CML Patients Carrying a Mutation T315I

Who this might be right for
Leukemia
Hospices Civils de Lyon 184
Testing effectiveness (Phase 2)Looking for participantsNCT06163430
What this trial is testing

A Phase 1/2 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of TERN-701 in Participants With Chronic Myeloid Leukemia (CARDINAL)

Who this might be right for
Chronic Myeloid Leukemia, Chronic PhaseChronic Myeloid Leukemia
Terns, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 180
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