Not applicableStudy completedNCT06534905What this trial is testingE-cigarette Switching Older AdultsWho this might be right forTobacco UseOpioid Use DisorderTobacco-Related Disorders University of Maryland, Baltimore 36
Not applicableStudy completedNCT00386945What this trial is testingTobacco Cessation Via Doctors of ChiropracticWho this might be right forTobacco Use Cessation Oregon Research Institute 201
Testing effectiveness (Phase 2)Looking for participantsNCT05121051What this trial is testingTesting the Effect of the Broccoli Seed and Sprout Extract, Avmacol ES, on the Cancer Causing Substances of Tobacco in Heavy SmokersWho this might be right forCigarette Smoking-Related Carcinoma National Cancer Institute (NCI) 135
Not applicableUnknownNCT04417075What this trial is testingMobile Smoking Treatment for Spanish-speaking Latinx SmokersWho this might be right forSmoking Cessation University of Houston 38
Not applicableStudy completedNCT07764549What this trial is testingSalivary TNF-α, FoxO-1, and SIRT-1 Levels in Periodontitis and SmokingWho this might be right forPeriodontitis (Stage 3)Smoking ( Cigarette) Zehra Hasgül 80
Not applicableStudy completedNCT05134415What this trial is testingUse Behavior, Nicotine Uptake, and Subjective Effects Comparison of Tobacco and Menthol e-Liquids by ENDS ConsumersWho this might be right forElectronic Cigarette Use Cheerain HK Limited 40
Post-approval studies (Phase 4)WithdrawnNCT02488889What this trial is testingEffects of Varenicline in Heavy Drinking SmokersWho this might be right forCigarette SmokingAlcohol Consumption University of California, Los Angeles
Not applicableNot Yet RecruitingNCT07612696What this trial is testingImpact of Electronic Cigarette Temperature and Solvent on BiomarkersWho this might be right forOxidative StressTobacco UseElectronic Cigarettes Milton S. Hershey Medical Center 50
Not applicableLooking for participantsNCT07661550What this trial is testingPrevention of Postpartum Smoking Relapse and Related Health Consequences by Breastfeeding PromotionWho this might be right forSmoking ( Cigarette)Breastfeeding State University of New York at Buffalo 280
Not applicableStudy completedNCT04844762What this trial is testingAddiction and Behavior Related to Menthol Cigarette SubstitutesWho this might be right forSmoking (Tobacco) Addiction Ohio State University Comprehensive Cancer Center 120
Not applicableStudy completedNCT03113136What this trial is testingExamination of Low Wattage and High Wattage E-CigarettesWho this might be right forSmoking, CigaretteSmoking, TobaccoNicotine Dependence+1 more Ohio State University Comprehensive Cancer Center 372
Early research (Phase 1)Study completedNCT01337830What this trial is testingPilot Study to Evaluate the Safety and Efficacy of Ariva® Silver Wintergreen in Reducing Cigarette Craving in SmokersWho this might be right forTobacco Use DisorderSmoking Star Scientific, Inc 111
Not applicableStudy completedNCT05023096What this trial is testingPotential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol SmokersWho this might be right forElectronic Nicotine Delivery System Flavors Virginia Commonwealth University 71
Not applicableNot Yet RecruitingNCT07604246What this trial is testingEvaluating the Effect of Nicotine on Eye Movements and Related Behaviors in Electronic Cigarette Users, NICS-EYES TrialWho this might be right forCigarette Smoking-Related Carcinoma Ohio State University Comprehensive Cancer Center 25
Large-scale testing (Phase 3)Looking for participantsNCT05257629What this trial is testingAggressive Smoking Cessation Trial (ASAP)Who this might be right forAcute Coronary SyndromeCardiovascular Diseases Sir Mortimer B. Davis - Jewish General Hospital 798
Not applicableEnded earlyNCT05569005What this trial is testingEffect of Switching From Cigarette Smoking to THS on Disease Progression in Mild to Moderate COPD Subjects With Chronic Bronchitis Symptoms.Who this might be right forCOPDSmokingTobacco Use Philip Morris Products S.A. 715
Not applicableStudy completedNCT04522362What this trial is testingModeling Stress-precipitated Vaping BehaviorWho this might be right forVaping Clemson University 51
Not applicableStudy completedNCT01526005What this trial is testingBrain Nicotine Receptor Density & Response to Nicotine PatchWho this might be right forCigarette Smoking Brentwood Biomedical Research Institute 50
Not applicableStudy completedNCT03839745What this trial is testingShort-Term Cardiovascular Effects of E-Cigarettes: Influence of Device PowerWho this might be right forCardiovascular Risk FactorNicotine Dependence University of California, San Francisco 16
Large-scale testing (Phase 3)Study completedNCT02521662What this trial is testingThe Use of Nicotine Patches Together With E-cigarettes (With and Without Nicotine) for Smoking CessationWho this might be right forSmoking Cessation University of Auckland, New Zealand 1,124