Post-approval studies (Phase 4)Study completedNCT02203162What this trial is testingEffect of Electronic Cigarette Use on Cough Reflex SensitivityWho this might be right forCough Montefiore Medical Center 30
Not applicableStudy completedNCT01921439What this trial is testingOCAST Cessation StudyWho this might be right forTobacco Smoking BehaviorCigarette Smoking BehaviorSecond Hand Tobacco Smoke+1 more University of Oklahoma 152
Not applicableStudy completedNCT03593239What this trial is testingComparing the Pharmacokinetics of Nicotine Salt Based ENDS in Healthy SmokersWho this might be right forNicotine DependenceNicotine Dependence, CigarettesTobacco Use+1 more Juul Labs, Inc. 24
Post-approval studies (Phase 4)Study completedNCT01664741What this trial is testingNicotine Dependence, Withdrawal and Replacement Therapy Assessed by PET ImagingWho this might be right forNicotine Dependence Johns Hopkins University 127
Not applicableStudy completedNCT02061917What this trial is testingSwitching From Usual Brand Cigarettes to a Tobacco-heating Cigarette or SnusWho this might be right forCigarette Smoking R.J. Reynolds Tobacco Company 163
Not applicableStudy completedNCT01627392What this trial is testingMechanisms of the Nicotine Metabolism Effect on Tobacco DependenceWho this might be right forCigarette Smoking University of California, San Francisco 305
Not applicableStudy completedNCT04522973What this trial is testingThe Impact of Oral Ethanol and Vaped Ethanol on the Evaluation of ImpairmentWho this might be right forElectronic Cigarette Use Virginia Commonwealth University 12
Not applicableStudy completedNCT05458895What this trial is testingEvaluating E-Cigarette Nicotine Form, Concentration, and Flavors Among YouthWho this might be right forE-cigarette Use Ohio State University Comprehensive Cancer Center 88
Not applicableNot Yet RecruitingNCT07274475What this trial is testingSmoking Harm Reduction Using E-cigarettes and CytisineWho this might be right forTobacco SmokingHarm ReductionNicotine Centre for Addiction and Mental Health 6,000
Not applicableStudy completedNCT03915730What this trial is testingSmoking and Peptidoglycan Recognition Protein-1 and Initial Periodontal TherapyWho this might be right forSmoking, Cigarette Kırıkkale University 80
Not applicableStudy completedNCT03885336What this trial is testingCouples Dynamics and Smoking CessationWho this might be right forSmokingSmoking CessationCessation, Smoking+2 more University of Southern California 212
Not applicableStudy completedNCT03364751What this trial is testingEffect of Switching From Cigarette Smoking to the Use of IQOS on Periodontitis Treatment OutcomeWho this might be right forPeriodontal DiseasesChronic PeriodontitisPeriodontal Pocket+3 more Philip Morris Products S.A. 179
Not applicableStudy completedNCT06534905What this trial is testingE-cigarette Switching Older AdultsWho this might be right forTobacco UseOpioid Use DisorderTobacco-Related Disorders University of Maryland, Baltimore 36
Early research (Phase 1)Study completedNCT03559751What this trial is testingEvaluation of the Abuse Liability of Very Low Nicotine (VLN) CigarettesWho this might be right forTobacco Use 22nd Century Group, Inc. 66
Not applicableStudy completedNCT00386945What this trial is testingTobacco Cessation Via Doctors of ChiropracticWho this might be right forTobacco Use Cessation Oregon Research Institute 201
Not applicableStudy completedNCT07764549What this trial is testingSalivary TNF-α, FoxO-1, and SIRT-1 Levels in Periodontitis and SmokingWho this might be right forPeriodontitis (Stage 3)Smoking ( Cigarette) Zehra Hasgül 80
Not applicableStudy completedNCT05134415What this trial is testingUse Behavior, Nicotine Uptake, and Subjective Effects Comparison of Tobacco and Menthol e-Liquids by ENDS ConsumersWho this might be right forElectronic Cigarette Use Cheerain HK Limited 40
Post-approval studies (Phase 4)WithdrawnNCT02488889What this trial is testingEffects of Varenicline in Heavy Drinking SmokersWho this might be right forCigarette SmokingAlcohol Consumption University of California, Los Angeles
Not applicableNot Yet RecruitingNCT07612696What this trial is testingImpact of Electronic Cigarette Temperature and Solvent on BiomarkersWho this might be right forOxidative StressTobacco UseElectronic Cigarettes Milton S. Hershey Medical Center 50
Not applicableLooking for participantsNCT07661550What this trial is testingPrevention of Postpartum Smoking Relapse and Related Health Consequences by Breastfeeding PromotionWho this might be right forSmoking ( Cigarette)Breastfeeding State University of New York at Buffalo 280