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Results for “Cognitively-normal”

37 trials

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Showing 20 of 37 results

Early research (Phase 1)Study completedNCT00757939
What this trial is testing

Assess Regional Cerebral Blood Flow as an Alzheimer's Disease Biomarker Compared to Positron Emission Tomography in Patients With Mild-to-Moderate Alzheimer's Disease and Cognitively Normal Elderly Subjects (Study MK-0000-068)(COMPLETED)

Who this might be right for
Alzheimer's Disease
Merck Sharp & Dohme LLC 40
Not applicableStudy completedNCT04421014
What this trial is testing

Ketone Ester Effects on Biomarkers of Brain Metabolism and Cognitive Performance in Cognitively Intact Adults 55 Years Old or Older

Who this might be right for
Metabolic SyndromeNormal Cognition
National Institute on Aging (NIA) 99
Post-approval studies (Phase 4)Study completedNCT00220896
What this trial is testing

Prevention of Postoperative Delirium With Donepezil

Who this might be right for
Cognitively Normal Elderly Individuals
Technical University of Munich 37
Post-approval studies (Phase 4)Study completedNCT01142336
What this trial is testing

Effects of Simvastatin on Biomarkers

Who this might be right for
Alzheimer's Disease
University of Washington 49
Large-scale testing (Phase 3)Ended earlyNCT01931566
What this trial is testing

Biomarker Qualification for Risk of Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease (AD) and Safety and Efficacy Evaluation of Pioglitazone in Delaying Its Onset

Who this might be right for
Mild Cognitive Impairment Due to Alzheimer's Disease
Takeda 3,494
Testing effectiveness (Phase 2)Study completedNCT00814346
What this trial is testing

Effect of EGb761® on Brain Glucose Metabolism in Three Groups of Elderly Defined by Cognitive Functions

Who this might be right for
Alzheimer's DiseaseCognitive Impairment
Ipsen 49
Very early researchEnded earlyNCT00811122
What this trial is testing

Biodistribution of 11C-PIB PET in Alzheimer's Disease, Frontotemporal Dementia, and Cognitively Normal Elderly

Who this might be right for
Alzheimer's Disease
University of Utah 2
Not applicableStudy completedNCT05980286
What this trial is testing

Impact of Music Improvisation Training on Cognitive Function in Older Adults

Who this might be right for
AgingCognitive AgingCognitive Impairment+3 more
University of California, San Francisco 53
Testing effectiveness (Phase 2)Looking for participantsNCT07477431
What this trial is testing

Levetiracetam for Persons at Risk for Alzheimer's Disease

Who this might be right for
Hippocampal HyperactivationProdromal Alzheimer Disease
Sunnybrook Health Sciences Centre 40
Not applicableLooking for participantsNCT06584357
What this trial is testing

Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia

Who this might be right for
Mild Cognitive ImpairmentAlzheimer's DiseaseAlzheimer's Disease, Early Onset+3 more
GAP Innovations, PBC 1,200
Not applicableLooking for participantsNCT03507257
What this trial is testing

Longitudinal Early-onset Alzheimer's Disease Study Protocol

Who this might be right for
Early Onset Alzheimer DiseaseAlzheimer DiseaseMild Cognitive Impairment
Indiana University 850
Not applicableLooking for participantsNCT06715995
What this trial is testing

Effects of Endogenous Gamma Light Stimulation on Brain Oscillations in Cognitively-normal Older Adults

Who this might be right for
EEG Brain OscillationsAlzheimer's Disease (AD)Cognitively Normal Older Adults
Chang Gung Memorial Hospital 52
Large-scale testing (Phase 3)Study completedNCT02913664
What this trial is testing

Risk Reduction for Alzheimer's Disease

Who this might be right for
Cognitively Normal Older AdultsHypertensionSubjective Cognitive Decline+1 more
University of Texas Southwestern Medical Center 513
Testing effectiveness (Phase 2)Study completedNCT02656498
What this trial is testing

[18F]THK-5351 Positron Emission Computed Tomography Study of Normal, Mild Cognitive Impairment, Alzheimer's Disease and Other Neurodegenerative Disease

Who this might be right for
Alzheimer's DiseaseMild Cognitive ImpairmentNeurodegenerative Diseases
Jae Seung Kim 135
Testing effectiveness (Phase 2)Looking for participantsNCT05331144
What this trial is testing

Impact of Intensive Treatment of SBP on Brain Perfusion, Amyloid, and Tau (IPAT Study)

Who this might be right for
Cognitively Normal Older AdultsHypertensionSubjective Cognitive Decline+1 more
Rong Zhang 180
Large-scale testing (Phase 3)Looking for participantsNCT05456503
What this trial is testing

PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620

Who this might be right for
Frontotemporal Lobar DegenerationAlzheimer DiseaseCognitively Normal
University of Pennsylvania 72
Not applicableStudy completedNCT05591313
What this trial is testing

Acute Exercise on Neurocognitive Function Among Adults With/Without Generic Risk of AD

Who this might be right for
Alzheimer Disease 2 Due to Apoe4 Isoform
National Taiwan Normal University 51
Not applicableStudy completedNCT05604365
What this trial is testing

FearLess in Cognitively Intact Patients With Glioma

Who this might be right for
GliomaFear of Cancer
Virginia Commonwealth University 22
Early research (Phase 1)Active Not RecruitingNCT05386914
What this trial is testing

This Study Consists of Two Study Parts Conducted Under a Single IRB. Part I: Short Term ApoE-dependent Cerebral Blood Flow Response to Sirolimus in Cognitively Normal Adults Part II: Short Term ApoE-dependent Cerebral Blood Flow and Lung Perfusion Response to Sirolimus in Cognitively Normal Adults

Who this might be right for
Genetic Predisposition to DiseaseHealthy Volunteers
University of Missouri-Columbia 205
Not applicableActive Not RecruitingNCT06721390
What this trial is testing

Music Improvisation Training on Cognitive Function in Older Adults

Who this might be right for
AgingCognitive AgingCognitive Impairment+3 more
University of California, San Francisco 238
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