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Results for “Cognitively-normal”

38 trials

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Showing 20 of 38 results

Not applicableLooking for participantsNCT06584357
What this trial is testing

Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia

Who this might be right for
Mild Cognitive ImpairmentAlzheimer's DiseaseAlzheimer's Disease, Early Onset+3 more
GAP Innovations, PBC 1,200
Not applicableStudy completedNCT00977418
What this trial is testing

Brain and Cognitive Changes After Reasoning or Physical Training in Cognitively Normal Seniors

Who this might be right for
Hearing Impaired
The University of Texas at Dallas 60
Not applicableStudy completedNCT01962779
What this trial is testing

Sleep, Aging and Risk for Alzheimer's Disease

Who this might be right for
Sleep Disordered BreathingAlzheimer's Disease
NYU Langone Health 235
Not applicableUnknownNCT05225181
What this trial is testing

Effects of the Combining Physical Exercise and Cognitive Training for the Community-based Elderly

Who this might be right for
Cognitively-normalMild Cognitive ImpairmentSubjective Cognitive Decline
Chang Gung Memorial Hospital 90
Not applicableStudy completedNCT03814603
What this trial is testing

The Sleep Amyloid, Slow WAve Race and Ethnicity Study

Who this might be right for
Alzheimer Disease
NYU Langone Health 210
Not applicableStudy completedNCT04421014
What this trial is testing

Ketone Ester Effects on Biomarkers of Brain Metabolism and Cognitive Performance in Cognitively Intact Adults 55 Years Old or Older

Who this might be right for
Metabolic SyndromeNormal Cognition
National Institute on Aging (NIA) 99
Not applicableActive Not RecruitingNCT03507257
What this trial is testing

Longitudinal Early-onset Alzheimer's Disease Study Protocol

Who this might be right for
Early Onset Alzheimer DiseaseAlzheimer DiseaseMild Cognitive Impairment
Indiana University 850
Not applicableStudy completedNCT05441865
What this trial is testing

Cardiovascular Risk Factors and Cognitive Trajectories

Who this might be right for
Normal CognitionCardiovascular Risk FactorsCognitive Change+2 more
Peking University Sixth Hospital 3,372
Large-scale testing (Phase 3)Looking for participantsNCT07752784
What this trial is testing

Evaluate the Concordance Between PET Imaging of [18F]-APN-1607 Injection and Postmortem Brain Tissue Tau Pathology in Individuals With HV and MCI or AD.

Who this might be right for
Alzheimer's Disease
JYAMS PET Research & Development Limited 12
Not applicableLooking for participantsNCT06715995
What this trial is testing

Effects of Endogenous Gamma Light Stimulation on Brain Oscillations in Cognitively-normal Older Adults

Who this might be right for
EEG Brain OscillationsAlzheimer's Disease (AD)Cognitively Normal Older Adults
Chang Gung Memorial Hospital 52
Large-scale testing (Phase 3)Looking for participantsNCT05456503
What this trial is testing

PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620

Who this might be right for
Frontotemporal Lobar DegenerationAlzheimer DiseaseCognitively Normal
University of Pennsylvania 72
Not applicableLooking for participantsNCT05776641
What this trial is testing

Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People at Risk for Alzheimer's Disease

Who this might be right for
Alzheimer DiseaseFamily Members
Massachusetts General Hospital 200
Post-approval studies (Phase 4)Study completedNCT00220896
What this trial is testing

Prevention of Postoperative Delirium With Donepezil

Who this might be right for
Cognitively Normal Elderly Individuals
Technical University of Munich 37
Early research (Phase 1)Study completedNCT05164536
What this trial is testing

Plasma P-tau2017 and Quantitative Amyloid PET Imaging

Who this might be right for
Alzheimer Disease
Invicro 140
Very early researchEnded earlyNCT00811122
What this trial is testing

Biodistribution of 11C-PIB PET in Alzheimer's Disease, Frontotemporal Dementia, and Cognitively Normal Elderly

Who this might be right for
Alzheimer's Disease
University of Utah 2
Not applicableLooking for participantsNCT06127667
What this trial is testing

Brain Vascular and Neural Function Linked to Balance Across the Adult Lifespan

Who this might be right for
NeurotypicalCognitively Normal
University of Minnesota 102
Not applicableStudy completedNCT05591313
What this trial is testing

Acute Exercise on Neurocognitive Function Among Adults With/Without Generic Risk of AD

Who this might be right for
Alzheimer Disease 2 Due to Apoe4 Isoform
National Taiwan Normal University 51
Early research (Phase 1)Active Not RecruitingNCT05386914
What this trial is testing

This Study Consists of Two Study Parts Conducted Under a Single IRB. Part I: Short Term ApoE-dependent Cerebral Blood Flow Response to Sirolimus in Cognitively Normal Adults Part II: Short Term ApoE-dependent Cerebral Blood Flow and Lung Perfusion Response to Sirolimus in Cognitively Normal Adults

Who this might be right for
Genetic Predisposition to DiseaseHealthy Volunteers
University of Missouri-Columbia 205
Not applicableStudy completedNCT03053908
What this trial is testing

Orexin and Tau Pathology in Cognitively Normal Elderly

Who this might be right for
ElderlyAlzheimer Disease
NYU Langone Health 25
Not applicableStudy completedNCT06364189
What this trial is testing

Inspiring Seniors Toward Exercise Promotion

Who this might be right for
Cognitively Normal Older Adults
University of North Carolina, Greensboro 54
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