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Results for “Complement Deficiency”

185 trials

Showing 20 of 185 results

Testing effectiveness (Phase 2)Looking for participantsNCT06419205
What this trial is testing

Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G

Who this might be right for
IgA NephropathyLupus Nephritis (LN)C3 (Complement Component 3) Glomerulopathy
Akebia Therapeutics 30
Early research (Phase 1)Study completedNCT02218294
What this trial is testing

Study to Determine How BCX4161 is Metabolized and Eliminated by the Body

Who this might be right for
Hereditary Angioedema
BioCryst Pharmaceuticals 7
Large-scale testing (Phase 3)Study completedNCT01188564
What this trial is testing

Efficacy, Safety and Immunogenicity Study of Recombinant Human C1 Inhibitor for the Treatment of Acute HAE Attacks

Who this might be right for
Hereditary Angioedema
Pharming Technologies B.V. 75
Large-scale testing (Phase 3)Study completedNCT06467084
What this trial is testing

Open-Label Safety, PK, and Efficacy Trial of Sebetralstat (KVD900) in Pediatric Patients (Ages 2-11) With HAE Type I or II

Who this might be right for
Hereditary Angioedema
KalVista Pharmaceuticals, Ltd. 36
Early research (Phase 1)Study completedNCT03202784
What this trial is testing

A Relative Bioavailability Study of Two Formulations of BCX7353

Who this might be right for
Hereditary Angioedema
BioCryst Pharmaceuticals 24
Testing effectiveness (Phase 2)Study completedNCT00851409
What this trial is testing

The Safety and Immunogenicity of Repeated rhC1INH Administration

Who this might be right for
Genetic DisordersHereditary Angioedema
Pharming Technologies B.V. 25
Large-scale testing (Phase 3)Study completedNCT00912093
What this trial is testing

Icatibant in Patients With Acute Attacks of Hereditary Angioedema (FAST-3)

Who this might be right for
Hereditary Angioedema
Shire 98
Not applicableEnded earlyNCT00006054
What this trial is testing

Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies

Who this might be right for
Immunologic Deficiency SyndromesChediak-Higashi SyndromeCommon Variable Immunodeficiency+11 more
Fairview University Medical Center
Not applicableApproved For MarketingNCT06628713
What this trial is testing

Treatment of Angioedema Attacks in Adolescent and Adult Patients 12 Years and Older With HAE Type I or II With Sebetralstat

Who this might be right for
Hereditary Angioedema
KalVista Pharmaceuticals, Ltd.
Not applicableEnded earlyNCT02854397
What this trial is testing

Determination of Specific Biomarkers of Acute Attack of Angioedema Within Pediatric Population

Who this might be right for
Hereditary AngioedemaHealthy Volunteers
University Hospital, Grenoble 31
Not applicableStudy completedNCT07009262
What this trial is testing

A Study Observing US Patients With HAE Type I or II Who Take Icatibant to Treat HAE Attacks

Who this might be right for
Hereditary Angioedema
KalVista Pharmaceuticals, Ltd. 88
Large-scale testing (Phase 3)Study completedNCT04070326
What this trial is testing

Lanadelumab to Prevent Hereditary Angioedema (HAE) Attacks in Children

Who this might be right for
Hereditary Angioedema
Shire 21
Not applicableStudy completedNCT04861090
What this trial is testing

A Study in Teenagers and Adults With Hereditary Angioedema (HAE) Type I or Type II Who Use Lanadelumab as Long-Term Prophylaxis

Who this might be right for
Hereditary Angioedema (HAE)
Takeda 207
Not applicableActive Not RecruitingNCT05397431
What this trial is testing

A Survey of Lanadelumab in Participants With Hereditary Angioedema

Who this might be right for
Hereditary Angioedema (HAE)
Takeda 155
Large-scale testing (Phase 3)Study completedNCT00457015
What this trial is testing

Efficacy Study of DX-88 (Ecallantide) to Treat Acute Attacks of Hereditary Angioedema (HAE)

Who this might be right for
Hereditary Angioedema (HAE)
Shire 96
Large-scale testing (Phase 3)Study completedNCT00168103
What this trial is testing

Human C1 Esterase Inhibitor (C1-INH) in Subjects With Acute Abdominal or Facial Hereditary Angioedema (HAE) Attacks

Who this might be right for
Hereditary Angioedema
CSL Behring 126
Not applicableStudy completedNCT04057131
What this trial is testing

FIRAZYR General Drug Use-Results Survey (Japan)

Who this might be right for
Hereditary Angioedema (HAE)
Shire 179
Post-approval studies (Phase 4)Study completedNCT00914966
What this trial is testing

Evaluate the Safety and Effect of Escalating Doses of CINRYZE

Who this might be right for
Hereditary Angioedema
Shire 20
Large-scale testing (Phase 3)WithdrawnNCT04898309
What this trial is testing

Efficacy and Safety of GNR-038 vs Berinert® in Patients With Hereditary Angioedema

Who this might be right for
Hereditary Angioedema
AO GENERIUM
Large-scale testing (Phase 3)Study completedNCT04180163
What this trial is testing

Efficacy and Safety of Lanadelumab (SHP643) in Japanese Participants With Hereditary Angioedema (HAE)

Who this might be right for
Hereditary Angioedema (HAE)
Shire 12
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