Not applicableAvailableNCT04288713What this trial is testingEculizumab (Soliris) in Covid-19 Infected PatientsWho this might be right forCoronavirus Hudson Medical
Testing effectiveness (Phase 2)Looking for participantsNCT06989359What this trial is testingPhase 2 Study of ADX-038 in Complement-Mediated Kidney DiseaseWho this might be right forIgANC3GComplement-mediated Kidney Disease+2 more ADARx Pharmaceuticals, Inc. 45
Testing effectiveness (Phase 2)Study completedNCT03124368What this trial is testingA Proof-of-Mechanism Study to Determine the Effect of Danicopan on C3 Levels in Participants With C3G or IC-MPGNWho this might be right forC3 GlomerulonephritisDense Deposit DiseaseC3 Glomerulopathy+2 more Alexion Pharmaceuticals, Inc. 6
Testing effectiveness (Phase 2)Looking for participantsNCT06853223What this trial is testingThis Study is Assessing the Safety and Efficacy of Immune Inhibition as a Treatment to Prevent Primary Graft DysfunctionWho this might be right forPrimary Graft DysfunctionLung TransplantationAcute Lung Injury(ALI)+1 more University of California, San Francisco 120
Not applicableStudy completedNCT01945307What this trial is testingComplement 2: Blood Donations to Develop Vaccines Against Infectious DiseasesWho this might be right forComplement Mediated Bacterial Killing in Healthy Adults University of Oxford 101
Early research (Phase 1)Study completedNCT02983006What this trial is testingStudy of DS-8273a With Nivolumab in Unresectable Stage III or Stage IV MelanomaWho this might be right forMelanoma NYU Langone Health 12
Early research (Phase 1)UnknownNCT06560593What this trial is testingClinical Trial of NTQ5082 in Healthy VolunteersWho this might be right forComplement-mediated Hemolytic Diseases Nanjing Chia-tai Tianqing Pharmaceutical 82
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05517980What this trial is testingEfficacy, Safety, Pharmacokinetics, and Pharmacodynamics of KP104 to Treat GlomerulonephritisWho this might be right forGlomerulonephritis Kira Pharmacenticals (US), LLC. 52
Not applicableActive Not RecruitingNCT05985122What this trial is testingNew Analytic Tools for aHUS and C3G DiagnosisWho this might be right forHemolytic-Uremic SyndromeMembranoproliferative GlomerulonephritisHealthy Mario Negri Institute for Pharmacological Research 180
Early research (Phase 1)Study completedNCT05937581What this trial is testingFirst-In-Human Study To Evaluate The Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Of Escalating Single And Multiple Doses Of CSL040 In Healthy SubjectsWho this might be right forComplement-mediated Disorders CSL Behring 62
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07363265What this trial is testingEfficacy and Safety of LP-005 Injection in Patients With Complement-Mediated Kidney DiseaseWho this might be right forComplement-mediated Renal Diseases Longbio Pharma 46
Not applicableEnded earlyNCT05095623What this trial is testingA Natural History Study to Assess the Clinical Outcomes of Patients With Complement Factor I Deficiency-Mediated DiseaseWho this might be right forRecurrent Bacterial Infection, Autoimmune Disorder Catalyst Biosciences 3
Early research (Phase 1)Looking for participantsNCT07462780What this trial is testingA Phase I Clinical Trial to Evaluate CMS-D017 Following Single and Multiple Doses in Healthy ParticipantsWho this might be right forParoxysmal Nocturnal Hemoglobinuria, PNHComplement-mediated Kidney Disease Shenzhen Kangzhe Biotechnology Co., Ltd. 88
Early research (Phase 1)Enrolling By InvitationNCT06723106What this trial is testingPhase 1b Long-term Extension Trial of RAY121 in Immunological Diseases (RAINBOW-LTE Trial)Who this might be right forAntiphospholipid Syndrome (APS)Bullous Pemphigoid (BP)Behçet's Syndrome (BS)+3 more Chugai Pharmaceutical 144
Not applicableNot Yet RecruitingNCT07331259What this trial is testingCHART-C3G/CLNP023B12011Who this might be right forC3 GlomerulopathyComplement-mediated Kidney DiseaseProteinuria Novartis Pharmaceuticals 83
Post-approval studies (Phase 4)Study completedNCT07290855What this trial is testingEvaluate the Safety and Efficacy of Icatibant in Patients With Bradykinin Induced AngioedemaWho this might be right forBradykinin-mediated AngioedemaHereditary Angioedema (HAE) Nang Kuang Pharmaceutical Co., Ltd. 5