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Results for “Congenital Blindness”

118 trials

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Showing 20 of 118 results

Not applicableUnknownNCT05765162
What this trial is testing

Safe Brain Initiative, Operationalizing Precision Anaesthesia

Who this might be right for
Neurocognitive DisordersPost Operative DeliriumPain+14 more
University of Southern Denmark 15,000
Not applicableLooking for participantsNCT03475173
What this trial is testing

New Non-invasive Modalities for Assessing Retinal Structure and Function

Who this might be right for
Ischemic Optic NeuropathyBranch Retinal Artery OcclusionHemianopia+2 more
Randy Kardon 500
Testing effectiveness (Phase 2)Active Not RecruitingNCT05676034
What this trial is testing

AMX0035 in Adult Patients With Wolfram Syndrome

Who this might be right for
Wolfram Syndrome
Amylyx Pharmaceuticals Inc. 12
Testing effectiveness (Phase 2)UnknownNCT05659368
What this trial is testing

Tirzepatide Monotherapy in Patients With Wolfram Syndrome Type 1

Who this might be right for
Wolfram Syndrome
Ospedale San Raffaele 10
Testing effectiveness (Phase 2)UnknownNCT04940572
What this trial is testing

Efficacy Study of Daily Administration of VPA in Patients Affected by Wolfram Syndrome

Who this might be right for
Wolfram Syndrome
Centre d'Etude des Cellules Souches 23
Testing effectiveness (Phase 2)UnknownNCT03872479
What this trial is testing

Single Ascending Dose Study in Participants With LCA10

Who this might be right for
Leber Congenital Amaurosis 10Inherited Retinal DystrophiesEye Diseases, Hereditary+4 more
Editas Medicine, Inc. 34
Large-scale testing (Phase 3)UnknownNCT04855045
What this trial is testing

An Open-label, Dose Escalation and Double-masked, Randomized, Controlled Trial Evaluating Safety and Tolerability of Sepofarsen in Children (<8 Years of Age) With LCA10 Caused by Mutations in the CEP290 Gene.

Who this might be right for
Leber Congenital Amaurosis 10BlindnessLeber Congenital Amaurosis+8 more
ProQR Therapeutics 15
Not applicableUnknownNCT05806684
What this trial is testing

Hyperbilirubinemia and Retinopathy of Prematurity in Preterm Infants: a Retrospective Study.

Who this might be right for
ROPJaundice, NeonatalPremature+3 more
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico 1,586
Not applicableStudy completedNCT04525261
What this trial is testing

Natural History of Patients With Inherited Retinal Diseases Due to Mutations in RPE65 Gene

Who this might be right for
Leber Congenital Amaurosis 2Retinitis Pigmentosa 20
University of Campania Luigi Vanvitelli 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT05203939
What this trial is testing

Study to Assess the Safety and Efficacy of OCU400 for Retinitis Pigmentosa and Leber Congenital Amaurosis

Who this might be right for
Retinitis PigmentosaLeber Congenital Amaurosis
Ocugen 22
Not applicableStudy completedNCT02946879
What this trial is testing

Long-Term Follow-Up Gene Therapy Study for Leber Congenital Amaurosis OPTIRPE65 (Retinal Dystrophy Associated With Defects in RPE65)

Who this might be right for
Leber Congenital Amaurosis (LCA)Eye DiseasesEye Diseases, Hereditary+1 more
MeiraGTx UK II Ltd 15
Testing effectiveness (Phase 2)Study completedNCT04355689
What this trial is testing

Safety and Efficacy of NPI-001 Tablets for RP Associated With Usher Syndrome

Who this might be right for
Usher Syndromes
Nacuity Pharmaceuticals, Inc. 49
Not applicableActive Not RecruitingNCT03602820
What this trial is testing

Long-term Follow-up Study in Subjects Who Received Voretigene Neparvovec-rzyl (AAV2-hRPE65v2)

Who this might be right for
Inherited Retinal Dystrophy Due to RPE65 Mutations
Genentech, Inc. 41
Testing effectiveness (Phase 2)Looking for participantsNCT06921317
What this trial is testing

GVB-2001 Gene Therapy Via Intracameral Injection for the Treatment of Primary Open Angle Glaucoma

Who this might be right for
Primary Open-Angle Glaucoma (POAG)
IVIEW Therapeutics Inc. 6
Not applicableUnknownNCT05764980
What this trial is testing

Neurovisual Function in CHARGE Syndrome

Who this might be right for
CHARGE Syndrome
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT03920007
What this trial is testing

Study of Subretinally Injected ATSN-101 Administered in Patients With Leber Congenital Amaurosis Caused by Biallelic Mutations in GUCY2D

Who this might be right for
Leber Congenital AmaurosisLCALCA1
Atsena Therapeutics Inc. 15
Not applicableEnrolling By InvitationNCT06938542
What this trial is testing

Palliative Care Needs of Children With Rare Diseases and Their Families

Who this might be right for
Trisomy 13 SyndromeArthrogryposis Congenita Multiplex With Intestinal AtresiaAsparagine Synthetase Deficiency+16 more
Children's National Research Institute 480
Early research (Phase 1)Study completedNCT01521793
What this trial is testing

Repeated Treatments of QLT091001 in Subjects With Leber Congenital Amaurosis or Retinitis Pigmentosa (Extension of Study RET IRD 01)

Who this might be right for
LCA (Leber Congenital Amaurosis)RP (Retinitis Pigmentosa)
QLT Inc. 27
Not applicableStudy completedNCT00016471
What this trial is testing

A Genetic Analysis of Usher Syndrome in Ashkenazi Jews

Who this might be right for
Usher SyndromeRetinitis PigmentosaCongenital Hearing Impairment
National Center for Research Resources (NCRR)
Very early researchUnknownNCT03566147
What this trial is testing

Treatment of RP and LCA by Primary RPE Transplantation

Who this might be right for
Leber Congenital Amaurosis, Retinitis Pigmentosa
Eyecure Therapeutics Inc. 30
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