Not applicableEnrolling By InvitationNCT03417856What this trial is testingDefining the Skin and Blood Biomarkers of IchthyosisWho this might be right forIchthyosisNetherton Syndrome Northwestern University 200
Early research (Phase 1)Study completedNCT01428297What this trial is testingA Study Evaluating the Safety and Efficacy of Topical BPR277 for the Treatment of Atopic Dermatitis and Netherton SyndromeWho this might be right forHealthy VolunteersAtopic DermatitisNetherton Syndrome Novartis Pharmaceuticals 12
Not applicableEnded earlyNCT00046202What this trial is testingStudy of Inborn Errors of Cholesterol Synthesis and Related DisordersWho this might be right forLysosomal Storage DiseaseCholesterol Metabolism Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 344
Not applicableStudy completedNCT05131542What this trial is testingAssessment of Hypotonia in Children With Down SyndromeWho this might be right forMuscle HypotoniaDown SyndromeMuscle, Floppy+2 more Universidad de Murcia 50
Testing effectiveness (Phase 2)Study completedNCT02864082What this trial is testingA Safety and Tolerability Study of Topical PAT-001 in Congenital IchthyosisWho this might be right forCongenital Ichthyosis Patagonia Pharmaceuticals, LLC 19
Testing effectiveness (Phase 2)Ended earlyNCT05979831What this trial is testingExplore Safety, Pharmacokinetics, and Early Clinical Signal of Efficacy of DS-2325a in Patients With Netherton SyndromeWho this might be right forNetherton Syndrome Daiichi Sankyo 9
Testing effectiveness (Phase 2)UnknownNCT05735158What this trial is testingTopical KB105 for the Treatment of TGM1-deficient Autosomal Recessive Congenital Ichthyosis (ARCI)Who this might be right forAutosomal Recessive Ichthyosis Krystal Biotech, Inc. 15
Not applicableStudy completedNCT02081313What this trial is testingNatural History and Biological Study of Netherton SyndromeWho this might be right forNetherton SyndromeHealthy Institut National de la Santé Et de la Recherche Médicale, France 18
Testing effectiveness (Phase 2)Study completedNCT03041038What this trial is testingThe Efficacy and Safety of Secukinumab in Patients With IchthyosesWho this might be right forIchthyosisAutosomal Recessive Congenital IchthyosisLamellar Ichthyosis+3 more Northwestern University 20
Not applicableNot Yet RecruitingNCT07477769What this trial is testingLymphocyte Phenotype of Autosomal Recessive Congenital Ichthyoses Mutated NIPAL4 (Nipal4-nEDD)Who this might be right forSezary SyndromeIchthyosis, Lamellar Assistance Publique - Hôpitaux de Paris 10
Not applicableStudy completedNCT00001292What this trial is testingStudy of Scaling Disorders and Other Inherited Skin DiseasesWho this might be right forGenetic Skin DiseaseKeratosis FollicularisLamellar Ichthyosis National Cancer Institute (NCI)
Large-scale testing (Phase 3)Study completedNCT00004690What this trial is testingPhase III Study of Monolaurin Cream Therapy for Patients With Congenital IchthyosisWho this might be right forIchthyosis Cellegy Pharmaceuticals 90
Not applicableUnknownNCT06123091What this trial is testingExploring Patient Reported Outcomes in Inherited IchthyosisWho this might be right forCongenital Ichthyosis Maastricht University Medical Center 20
Large-scale testing (Phase 3)Ended earlyNCT05856526What this trial is testingTest Whether Spesolimab Helps People With a Skin Disease Called Netherton SyndromeWho this might be right forNetherton Syndrome Boehringer Ingelheim 43
Early research (Phase 1)Looking for participantsNCT06539507What this trial is testingThe Safety, Tolerability, Pharmacokinetics, and Immunogenicity of BCX17725Who this might be right forNetherton Syndrome BioCryst Pharmaceuticals 78
Large-scale testing (Phase 3)Study completedNCT01222000What this trial is testingTreatment of the Recessive Nonbullous Congenital Ichthyosis by the Epigallocatechine CutaneousWho this might be right forLamellar Ichthyosis Centre Hospitalier Universitaire de Nice 6
Testing effectiveness (Phase 2)Study completedNCT02113904What this trial is testingClinical Trial Using Humira in Netherton SyndromeWho this might be right forNetherton Syndrome Assistance Publique - Hôpitaux de Paris 11
Post-approval studies (Phase 4)UnknownNCT04996485What this trial is testingScientific Substantiation and Assessment of the Effectiveness of Pathogenetic Methods of Therapy for Congenital Ichthyosis in ChildrenWho this might be right forCongenital Ichthyosis National Medical Research Center for Children's Health, Russian Federation 50
Not applicableLooking for participantsNCT07280091What this trial is testingStudy of Skin and Gut Microbiome in a Skin Condition Involving Skin Barrier Impairment and Allergic Symptoms: Netherton SyndromeWho this might be right forNetherton Syndrome Assistance Publique - Hôpitaux de Paris 30
Large-scale testing (Phase 3)Looking for participantsNCT05789056What this trial is testingOpen Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton SyndromeWho this might be right forNetherton Syndrome Quoin Pharmaceuticals 20