Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Controlled Human Malaria Infection (CHMI)”

29 trials

Showing 20 of 29 results

Early research (Phase 1)Study completedNCT03163121
What this trial is testing

Safety and Protective Efficacy of Genetically Attenuated PfSPZ-GA1 Vaccine in Healthy Dutch Volunteers

Who this might be right for
Malaria
Sanaria Inc. 67
Early research (Phase 1)Study completedNCT03882528
What this trial is testing

Evaluate the Infectivity Equivalence of Current and New Lots of Plasmodium Falciparum Strain NF54

Who this might be right for
Malaria,Falciparum
U.S. Army Medical Research and Development Command 12
Early research (Phase 1)Study completedNCT03014258
What this trial is testing

A Systems Biology Approach to Malaria Immunity

Who this might be right for
Plasmodium Falciparum Infection
National Institute of Allergy and Infectious Diseases (NIAID) 27
Early research (Phase 1)Study completedNCT02015091
What this trial is testing

Study of Controlled Human Malaria Infections to Evaluate Protection After Intravenous or Intramuscular Administration of PfSPZ Vaccine in Malaria-Naive Adults

Who this might be right for
Malaria
National Institute of Allergy and Infectious Diseases (NIAID) 141
Early research (Phase 1)Study completedNCT03867331
What this trial is testing

To Assess the Safety, Immunogenicity and Efficacy of VLPM01 in Healthy, Malaria-Naïve Volunteers

Who this might be right for
Malaria,Falciparum
VLP Therapeutics 36
Early research (Phase 1)UnknownNCT04268420
What this trial is testing

A Trial For The Study of Falciparum Malaria Protein 013 Administered Via Intramuscular Injection in Healthy Adults

Who this might be right for
Vaccine Reaction
U.S. Army Medical Research and Development Command 46
Early research (Phase 1)UnknownNCT04296279
What this trial is testing

A Trial For The Study of Falciparum Malaria Protein 014 Administered Via Intramuscular Injection in Healthy Adults

Who this might be right for
Vaccine Reaction
U.S. Army Medical Research and Development Command 46
Early research (Phase 1)Study completedNCT02704533
What this trial is testing

Sequential Optimization of Dose and Schedule of PfSPZ Vaccine

Who this might be right for
Malaria
Sanaria Inc. 45
Early research (Phase 1)Study completedNCT04206332
What this trial is testing

Trial to Evaluate CIS43LS in Healthy Adults

Who this might be right for
Malaria
National Institute of Allergy and Infectious Diseases (NIAID) 71
Testing effectiveness (Phase 2)Temporarily pausedNCT04280692
What this trial is testing

Controlled Human Malaria Infection Transmission Model - Phase A

Who this might be right for
Malaria,Falciparum
University of Oxford 44
Testing effectiveness (Phase 2)WithdrawnNCT03278808
What this trial is testing

Chloroquine (CQ) and Azithromycin (AZ) Combination for Malaria Prophylaxis

Who this might be right for
Malaria
U.S. Army Medical Research and Development Command
Early research (Phase 1)Not Yet RecruitingNCT07730177
What this trial is testing

Challenge Trial of PfSPZ-LARC2 Vaccine in Burkina Faso

Who this might be right for
Malaria (Plasmodium Falciparum)
Sanaria Inc. 45
Early research (Phase 1)Study completedNCT05891236
What this trial is testing

Safety, Tolerability, Pharmacokinetics and Protective Efficacy of MAM01 in Healthy Adults

Who this might be right for
Malaria
Gates Medical Research Institute 63
Early research (Phase 1)Study completedNCT07816497
What this trial is testing

Controlled Human Malaria Infection by Mosquito Bites Using a Local Strain of Plasmodium Falciparum

Who this might be right for
Malaria (Plasmodium Falciparum)
Centre de Recherche Médicale de Lambaréné 20
Early research (Phase 1)Study completedNCT01624961
What this trial is testing

Controlled Human Malarial Infection by Intravenous Injection of Plasmodium Falciparum Sporozoites in Non-Immune Adults

Who this might be right for
Malaria
Sanaria Inc. 30
Early research (Phase 1)Study completedNCT02215707
What this trial is testing

A Clinical Trial of the PfSPZ Vaccine Administered by Direct Venous Inoculation in Healthy Malaria-Naïve Adults: Heterologous vs. Homologous Controlled Human Malaria Infection and Reduction in Number of Doses

Who this might be right for
Malaria
Sanaria Inc. 67
Early research (Phase 1)Ended earlyNCT05604521
What this trial is testing

Trial of PfSPZ Vaccine in Healthy Adults to Determine Safety, Tolerability and Efficacy Against Heterologous CHMI

Who this might be right for
MalariaMalaria,Falciparum
Sanaria Inc. 31
Early research (Phase 1)Looking for participantsNCT06862453
What this trial is testing

Safety, Tolerability and Efficacy of PfSPZ-LARC2 Vaccine Against CHMI in Malaria-Naïve Adults

Who this might be right for
Malaria Falciparum
Sanaria Inc. 58
Early research (Phase 1)UnknownNCT02739763
What this trial is testing

Controlled Human Malaria Infection in Semi-Immune Kenyan Adults. (CHMI-SIKA)

Who this might be right for
Malaria
University of Oxford 200
Early research (Phase 1)Study completedNCT01728701
What this trial is testing

Controlled Human Malaria Infection (CHMI) After Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis

Who this might be right for
MalariaPlasmodium Falciparum
Sanaria Inc. 30
Next Page

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation