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Results for “Cryopyrin-Associated Periodic Syndromes (CAPS)”

37 trials

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Showing 20 of 37 results

Large-scale testing (Phase 3)Study completedNCT00991146
What this trial is testing

Efficacy and Safety Study of Canakinumab Administered for 6 Months (24 Weeks) in Japanese Patients With Cryopyrin-associated Periodic Syndromes Followed by an Extension Phase

Who this might be right for
Cryopyrin-associated Periodic SyndromesFamilial Cold Autoinflammatory SyndromeMuckle-Wells Syndrome+1 more
Novartis Pharmaceuticals 19
Early research (Phase 1)Study completedNCT02175056
What this trial is testing

A Dose-Block Randomized, Placebo Controlled (Double-blind), Active Controlled(Open-label), Dose-escalation Study

Who this might be right for
Healthy Volunteers
Handok Inc. 58
Testing effectiveness (Phase 2)WithdrawnNCT01211977
What this trial is testing

A Pilot Study of XOMA 052 in Familial Cold Autoinflammatory Syndrome / Muckle-Wells Syndrome and Behcet's Disease

Who this might be right for
Muckle Wells SyndromeAutoinflammatoryBehcet's Disease
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Not applicableNot Yet RecruitingNCT05292768
What this trial is testing

Are Mast Cells Involved in Autoinflammatory Diseases

Who this might be right for
Autoinflammatory DiseaseFMFTRAPS+3 more
Assistance Publique - Hôpitaux de Paris 590
Not applicableStudy completedNCT00887939
What this trial is testing

Pathogenesis of Physical Induced Urticarial Syndromes

Who this might be right for
Hypersensitivity, ImmediateAutoinflammatory SyndromesPhysical Urticaria+1 more
National Institute of Allergy and Infectious Diseases (NIAID) 173
Large-scale testing (Phase 3)Study completedNCT01105507
What this trial is testing

The Safety and Efficacy of Canakinumab in Patients Aged 4 Years or Older Diagnosed With Cryopyrin-associated Periodic Syndromes (CAPS) in Canada

Who this might be right for
Cryopyrin Associated Periodic Syndrome
Novartis Pharmaceuticals 4
Not applicableUnknownNCT03566615
What this trial is testing

Does the Cap Increase the Finding of Polyps When Water Exchange Colonoscopy is Used

Who this might be right for
ColonoscopyPolyp of Colon
VA Greater Los Angeles Healthcare System 1,630
Not applicableEnded earlyNCT03219918
What this trial is testing

Adenoma Detection Rate in Colonoscopy Performed With EndoRings

Who this might be right for
Colorectal AdenomaColorectal Neoplasms
Zealand University Hospital 97
Testing effectiveness (Phase 2)Study completedNCT00094900
What this trial is testing

Interleukin-1 Trap to Treat Autoinflammatory Diseases

Who this might be right for
InflammationFamilial Mediterranean FeverStill's Disease, Adult-Onset
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) 11
Testing effectiveness (Phase 2)Ended earlyNCT04524858
What this trial is testing

Study of ATI-450 in Patients With Cryopyrin-Associated Periodic Syndrome (CAPS)

Who this might be right for
Cryopyrin-Associated Periodic Syndrome
Aclaris Therapeutics, Inc. 1
Testing effectiveness (Phase 2)Study completedNCT00487708
What this trial is testing

Safety, Efficacy, Pharmacokinetics, Pharmacodynamics of ACZ885 in Patients With NALP3 Mutations and Clinical Symptoms

Who this might be right for
NALP3 Mutation
Novartis Pharmaceuticals 34
Testing effectiveness (Phase 2)Study completedNCT01045772
What this trial is testing

Safety and Tolerability of Rilonacept in Muckle-Wells Syndrome (MWS) or Schnitzler Syndrome (SchS)

Who this might be right for
Muckle-Wells SyndromeSchnitzler Syndrome
Charite University, Berlin, Germany 10
Not applicableStudy completedNCT04856540
What this trial is testing

Adult Outcomes of Children With CAPS

Who this might be right for
Cryopyrin Associated Periodic Syndrome
University Hospital, Lille 54
Early research (Phase 1)Study completedNCT04086602
What this trial is testing

Safety and Tolerability, Pharmacokinetic and Pharmacodynamic Study With IZD334

Who this might be right for
Healthy VolunteersCryopyrin Associated Periodic Syndrome
Inflazome UK Ltd 64
Testing effectiveness (Phase 2)Study completedNCT04868968
What this trial is testing

Study of Safety, Tolerability and Efficacy of DFV890 in Participants With Familial Cold Auto-inflammatory Syndrome (FCAS)

Who this might be right for
Familial Cold Autoinflammatory Syndrome
Novartis Pharmaceuticals 4
Early research (Phase 1)Study completedNCT04015076
What this trial is testing

Safety and Tolerability, Pharmacokinetic and Pharmacodynamic Study With Inzomelid

Who this might be right for
Healthy
Inflazome UK Ltd 80
Large-scale testing (Phase 3)Study completedNCT01302860
What this trial is testing

Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease

Who this might be right for
Cryopyrin-associated Periodic SyndromesFamilial Cold Autoinflammatory SyndromeMuckle-Wells Syndrome+1 more
Novartis Pharmaceuticals 17
Early research (Phase 1)Looking for participantsNCT06974877
What this trial is testing

Repeat PET/CT Imaging in People With CAPS and Anakinra-Induced Amyloidosis Using an Amyloid-Reactive Peptide to Measure Changes in Organ-Specific Amyloid Load

Who this might be right for
Cryopyrin-Associated Periodic SyndromesAmyloidosis
National Institute of Allergy and Infectious Diseases (NIAID) 30
Large-scale testing (Phase 3)Ended earlyNCT00770601
What this trial is testing

Canakinumab to Treat Neonatal-Onset Multisystem Inflammatory Disease

Who this might be right for
NOMIDCINCA Syndrome
Novartis Pharmaceuticals 7
Large-scale testing (Phase 3)Study completedNCT02334748
What this trial is testing

Canakinumab in Patients With Systemic Juvenile Idiopathic Arthritis or Hereditary Periodic Fevers Who Participated in the CACZ885G2301E1, CACZ885G2306 or CACZ885N2301 Studies

Who this might be right for
Systemic Juvenile Idiopathic ArthritisHereditary Periodic Fevers
Novartis Pharmaceuticals 31
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