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Results for “DEE”

21 trials

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Showing 20 of 21 results

Large-scale testing (Phase 3)Not Yet RecruitingNCT07723976
What this trial is testing

Evaluate the Safety and Efficacy of CBD-OS in Participants With DEE

Who this might be right for
Developmental and Epileptic Encephalopathy (DEE)
Jazz Pharmaceuticals 120
Large-scale testing (Phase 3)Active Not RecruitingNCT05818553
What this trial is testing

A Clinical Trial of PRAX-562 in Subjects With Developmental and Epileptic Encephalopathies (DEE)

Who this might be right for
SCN2A EncephalopathySCN8A Encephalopathy
Praxis Precision Medicines 77
Testing effectiveness (Phase 2)Looking for participantsNCT06401538
What this trial is testing

BMB-101 in Absence Epilepsy and DEE

Who this might be right for
Absence EpilepsyJeavons SyndromeDravet Syndrome+1 more
Bright Minds Biosciences Pty Ltd 20
Not applicableEnded earlyNCT04537832
What this trial is testing

Natural History Study of Infants and Children With Developmental and Epileptic Encephalopathies

Who this might be right for
Dravet Syndrome
Encoded Therapeutics 58
Not applicableNot Yet RecruitingNCT07585643
What this trial is testing

IBIS - Investigating Reliability of BIS and SEDLINE Monitoring in Children With Developmental and Epileptic Encephalopathies (DEE).

Who this might be right for
Epileptic EncephalopathyEarly Infantile Epileptic EncephalopathyInfantile Spasm+1 more
Telethon Kids Institute 40
Testing effectiveness (Phase 2)Ended earlyNCT04873869
What this trial is testing

Study to Evaluate NBI-921352 as Adjunctive Therapy in Subjects With SCN8A Developmental and Epileptic Encephalopathy Syndrome (SCN8A-DEE)

Who this might be right for
SCN8A Developmental and Epileptic Encephalopathy Syndrome
Neurocrine Biosciences 8
Large-scale testing (Phase 3)Ended earlyNCT04912856
What this trial is testing

An Open-Label Extension of the Study XEN496 (Ezogabine) in Children With KCNQ2-DEE

Who this might be right for
EpilepsyEpilepsy in ChildrenEpilepsy; Seizure+5 more
Xenon Pharmaceuticals Inc. 8
Testing effectiveness (Phase 2)Ended earlyNCT05226780
What this trial is testing

Extension Study to Evaluate How Safe and Tolerable NBI-921352 is as an Adjunctive Therapy for Participants With SCN8A-DEE

Who this might be right for
SCN8A Developmental and Epileptic Encephalopathy Syndrome
Neurocrine Biosciences 8
Not applicableLooking for participantsNCT07531511
What this trial is testing

SLC6A1-NDD Prospective Longitudinal Natural History Study

Who this might be right for
SLC6A1 Neurodevelopmental Disorder (NDD)Developmental and Epileptic Encephalopathies (DEE)
UCB Biopharma SRL 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT05737784
What this trial is testing

A Clinical Trial of PRAX-222 in Pediatric Participants With Early Onset SCN2A Developmental and Epileptic Encephalopathy

Who this might be right for
SCN2A-DEEEpilepsy
Praxis Precision Medicines 60
Not applicableLooking for participantsNCT07413211
What this trial is testing

Genetic Developmental and Epileptic Encephalopathy Natural History Study for Clinical Trial Readiness

Who this might be right for
MEF2CDEE
Weill Medical College of Cornell University 22,068
Large-scale testing (Phase 3)Active Not RecruitingNCT07010471
What this trial is testing

A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine

Who this might be right for
Developmental and Epileptic Encephalopathy 1
Praxis Precision Medicines 160
Large-scale testing (Phase 3)Looking for participantsNCT07019922
What this trial is testing

A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety

Who this might be right for
Epileptic EncephalopathySCN2A Encephalopathy
Praxis Precision Medicines 40
Large-scale testing (Phase 3)Active Not RecruitingNCT06719141
What this trial is testing

Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)

Who this might be right for
Developmental and Epileptic Encephalopathy
Longboard Pharmaceuticals 367
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07221968
What this trial is testing

Melatonin for the Treatment of DEE-SWAS

Who this might be right for
CSWSDevelopmental and/or Epileptic EncephalopathiesElectrical Status Epilepticus in Sleep
Hugo W. Moser Research Institute at Kennedy Krieger, Inc. 3
Not applicableLooking for participantsNCT06380192
What this trial is testing

Developmental and Epileptic Encephalopathy of Genetic Etiology: Natural History Through Reuse of Clinical Data

Who this might be right for
Developmental and Epileptic Encephalopathy
Imagine Institute 400
Not applicableStudy completedNCT05407727
What this trial is testing

A Prospective, Remote Observational Study in Pediatric Participants With Early-Onset SCN2A-Developmental and Epileptic Encephalopathy

Who this might be right for
SCN2A-DEEEpilepsy
Praxis Precision Medicines 5
Not applicableNot Yet RecruitingNCT07396883
What this trial is testing

Developmental and Epileptic Encephalopathies Diagnosed Via Long-read Genome Sequencing

Who this might be right for
Developmental and Epileptic EncephalopathyEpilepsy in Children
University Hospital, Strasbourg, France 20
Testing effectiveness (Phase 2)Looking for participantsNCT05419492
What this trial is testing

A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome

Who this might be right for
Dravet Syndrome
Encoded Therapeutics 47
Testing effectiveness (Phase 2)Active Not RecruitingNCT06112275
What this trial is testing

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (Australia Only)

Who this might be right for
Dravet Syndrome
Encoded Therapeutics 4
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