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Results for “DIPG”

89 trials

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Showing 20 of 89 results

Early research (Phase 1)Looking for participantsNCT04099797
What this trial is testing

C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)

Who this might be right for
Diffuse Intrinsic Pontine GliomaHigh Grade GliomaEmbryonal Tumor+1 more
Baylor College of Medicine 37
Early research (Phase 1)Active Not RecruitingNCT03389802
What this trial is testing

Phase I Study of APX005M in Pediatric Central Nervous System Tumors

Who this might be right for
Glioblastoma MultiformeHigh-grade Astrocytoma Not Otherwise Specified (NOS)CNS Primary Tumor, Not Otherwise Specified (NOS)+3 more
Pediatric Brain Tumor Consortium 32
Testing effectiveness (Phase 2)Study completedNCT02960230
What this trial is testing

H3.3K27M Peptide Vaccine With Nivolumab for Children With Newly Diagnosed DIPG and Other Gliomas

Who this might be right for
Diffuse Intrinsic Pontine GliomaGliomaDiffuse Midline Glioma, H3 K27M-Mutant
Sabine Mueller, MD, PhD 50
Testing effectiveness (Phase 2)Study completedNCT01189266
What this trial is testing

Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Who this might be right for
Anaplastic AstrocytomaAnaplastic OligoastrocytomaDiffuse Intrinsic Pontine Glioma+1 more
National Cancer Institute (NCI) 79
Early research (Phase 1)Study completedNCT01222754
What this trial is testing

Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas

Who this might be right for
Diffuse Intrinsic Pontine GliomaAnaplastic AstrocytomaHigh Grade Glioma
National Cancer Institute (NCI) 29
Not applicableUnknownNCT04670016
What this trial is testing

HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their Caregivers

Who this might be right for
DIPGBrain Tumor, Pediatric, RecurrentBrain Tumor, DIPG+3 more
University of Calgary 57
Testing effectiveness (Phase 2)Study completedNCT01469247
What this trial is testing

Diffuse Intrinsic Pontine Glioma (DIPG) Reirradiation (ReRT)

Who this might be right for
Brain Cancer
M.D. Anderson Cancer Center 12
Early research (Phase 1)Study completedNCT02644460
What this trial is testing

Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaBrain Tumor, RecurrentSolid Tumor, Recurrent+5 more
Emory University 53
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07206849
What this trial is testing

Study of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG)

Who this might be right for
High Grade Glioma (HGG) of the Brain With BRAF AberrationHigh Grade Glioma (III or IV)Diffuse Intrinsic Pontine Glioma+4 more
Nationwide Children's Hospital 79
Early research (Phase 1)Study completedNCT04295759
What this trial is testing

INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas

Who this might be right for
Glioblastoma MultiformeAnaplastic AstrocytomaAnaplastic Oligodendroglioma+3 more
Pediatric Brain Tumor Consortium 13
Early research (Phase 1)UnknownNCT02840123
What this trial is testing

Safety Study of DIPG Treatment With Autologous Dendritic Cells Pulsed With Lysated Allegenic Tumor Lines

Who this might be right for
Diffuse Intrinsic Pontine Glioma
Fundació Sant Joan de Déu 10
Testing effectiveness (Phase 2)Study completedNCT02750891
What this trial is testing

DSP-7888 in Pediatric Patients With Relapsed or Refractory High Grade Gliomas

Who this might be right for
GlioblastomaDiffuse Intrinsic Pontine Glioma
Sumitomo Pharma Co., Ltd. 18
Testing effectiveness (Phase 2)Looking for participantsNCT06838676
What this trial is testing

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

Who this might be right for
Diffuse Intrinsic Pontine Gliomas (DIPG)Progressive DIPGRefractory DIPG+2 more
Nationwide Children's Hospital 60
Early research (Phase 1)Active Not RecruitingNCT02359565
What this trial is testing

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma

Who this might be right for
Constitutional Mismatch Repair Deficiency SyndromeLynch SyndromeMalignant Glioma+8 more
National Cancer Institute (NCI) 71
Testing effectiveness (Phase 2)Active Not RecruitingNCT04758533
What this trial is testing

Clinical Trial to Assess the Safety and Efficacy of AloCELYVIR With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) in Combination With Radiotherapy or Medulloblastoma in Monotherapy

Who this might be right for
Diffuse Intrinsic Pontine GliomaMedulloblastoma, Childhood, Recurrent
Hospital Infantil Universitario Niño Jesús, Madrid, Spain 13
Testing effectiveness (Phase 2)Study completedNCT03566199
What this trial is testing

MTX110 by Convection-Enhanced Delivery in Treating Participants With Newly-Diagnosed Diffuse Intrinsic Pontine Glioma

Who this might be right for
Diffuse Intrinsic Pontine Glioma
Sabine Mueller, MD, PhD 7
Early research (Phase 1)Active Not RecruitingNCT04808245
What this trial is testing

Phase I Peptide VaCcine Trial for the Treatment of H3-Mutated Gliomas

Who this might be right for
Newly Diagnosed H3-mutated Glioma
German Cancer Research Center 15
Early research (Phase 1)Looking for participantsNCT06221553
What this trial is testing

Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPG

Who this might be right for
DIPG Brain TumorDiffuse Intrinsic Pontine Glioma
Chulalongkorn University 9
Very early researchActive Not RecruitingNCT03893487
What this trial is testing

Fimepinostat in Treating Brain Tumors in Children and Young Adults

Who this might be right for
Diffuse Intrinsic Pontine GliomaRecurrent Anaplastic AstrocytomaRecurrent Glioblastoma+2 more
Sabine Mueller, MD, PhD 30
Early research (Phase 1)Looking for participantsNCT04943848
What this trial is testing

RHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-Mutant
Ann & Robert H Lurie Children's Hospital of Chicago 36
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