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Results for “DM1”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT00679341
What this trial is testing

The Efficacy and Safety of Trastuzumab Emtansine (Trastuzumab-MCC-DM1) vs. Trastuzumab (Herceptin®) and Docetaxel (Taxotere®) in Patients With Metastatic HER2-positive Breast Cancer Who Have Not Received Prior Chemotherapy for Metastatic Disease

Who this might be right for
Breast Cancer
Hoffmann-La Roche 137
Large-scale testing (Phase 3)WithdrawnNCT04700046
What this trial is testing

Study to Investigate the Efficacy and Safety of Mexiletine in Patients With Myotonic Dystrophy Type 1 and Type 2

Who this might be right for
Myotonic Dystrophy Type 1 and Type 2
Lupin Ltd.
Testing effectiveness (Phase 2)Study completedNCT03530696
What this trial is testing

T-DM1 and Palbociclib for Metastatic HER2 Breast Cancer

Who this might be right for
HER2-positive Breast CancerBreast CancerBreast Cancer Stage+3 more
University of Arizona 55
Testing effectiveness (Phase 2)Study completedNCT00509769
What this trial is testing

Trastuzumab Emtansine (Trastuzumab-MCC-DM1) Administered Intravenously to Patients With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer
Genentech, Inc. 112
Not applicableStudy completedNCT03589677
What this trial is testing

Brain Involvement in Myotonic Dystrophy Type I: From Functional Neuroimaging to the Impact on Quality of Life

Who this might be right for
Myotonic Dystrophy Type 1 (DM1)
IRCCS San Camillo, Venezia, Italy 50
Not applicableStudy completedNCT04835298
What this trial is testing

Breathlessness Assessment in Adult Patients With Myotonic Dystrophy Type 1

Who this might be right for
Myotonic Dystrophy Type 1 (DM1)
CHU de Reims 34
Large-scale testing (Phase 3)Enrolling By InvitationNCT07008469
What this trial is testing

Global Open-Label Extension Study of Del-desiran for the Treatment of DM1

Who this might be right for
Myotonic Dystrophy Type 1DM1Myotonic Dystrophy+5 more
Avidity Biosciences, Inc. 199
Testing effectiveness (Phase 2)Study completedNCT00934856
What this trial is testing

Trastuzumab Emtansine (T-DM1) in Combination With Docetaxel, and Potentially Pertuzumab, in Participants With Advanced Breast Cancer

Who this might be right for
Breast Cancer
Hoffmann-La Roche 98
Testing effectiveness (Phase 2)Study completedNCT01835236
What this trial is testing

Trastuzumab & Pertuzumab Followed by T-DM1 in MBC

Who this might be right for
Metastatic Breast Cancer
Swiss Cancer Institute 208
Testing effectiveness (Phase 2)Ended earlyNCT03784599
What this trial is testing

T-DM1 and Osimertinib Combination Treatment to Target HER2 Bypass Track Resistance in EGFR Mutation Positive NSCLC

Who this might be right for
Carcinoma, Non-Small-Cell Lung
The Netherlands Cancer Institute 28
Not applicableLooking for participantsNCT05982119
What this trial is testing

Assessments in Patients With Muscular Pathology and in Control Subjects : The ActiLiège Next Study

Who this might be right for
Duchenne Muscular DystrophyFascioscapulohumeral Muscular DystrophyMyotonic Dystrophy 1+3 more
Centre Hospitalier Universitaire de Liege 300
Not applicableActive Not RecruitingNCT06809049
What this trial is testing

Music Intervention for Brain-Heart Disease in Myotonic Dystrophy Type 1 (DM1)

Who this might be right for
Myotonic Dystrophy, CongenitalMyotonic Dystrophy, Type 1 (DM1)Myotonic Dystrophy Type 1+1 more
Hanns Lochmuller 13
Not applicableLooking for participantsNCT03981575
What this trial is testing

Estab Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1)

Who this might be right for
Myotonic Dystrophy 1DM1
Virginia Commonwealth University 700
Early research (Phase 1)Study completedNCT01983501
What this trial is testing

Tucatinib (ONT-380) Combined With Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2+ Breast Cancer

Who this might be right for
HER2 Positive Breast Cancers
Seagen Inc. 57
Not applicableLooking for participantsNCT02398786
What this trial is testing

Myotonic Dystrophy Family Registry

Who this might be right for
Myotonic DystrophyCongenital Myotonic DystrophyMyotonic Dystrophy 1+13 more
Myotonic Dystrophy Foundation 3,500
Testing effectiveness (Phase 2)Study completedNCT00577577
What this trial is testing

Safety and Efficacy Study of Recombinant Human Insulin-Like Growth Factor-I/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 (rhIGF-I/rhIGFBP-3) In Myotonic Dystrophy Type 1

Who this might be right for
Myotonic Dystrophy Type 1
Insmed Incorporated 69
Not applicableStudy completedNCT04187482
What this trial is testing

Myotonic Dystrophy Type 1 Aerobic Exercise Study

Who this might be right for
Myotonic Dystrophy 1Muscular Dystrophies
McMaster University 13
Testing effectiveness (Phase 2)Study completedNCT01745965
What this trial is testing

A Prospective, Randomized Multicenter, Open-label Comparison of Preoperative Trastuzumab Emtansine (T-DM1) With or Without Standard Endocrine Therapy vs. Trastuzumab With Standard Endocrine Therapy Given for Twelve Weeks in Patients With Operable HER2+/HR+ Breast Cancer Within the ADAPT Protocol.

Who this might be right for
Breast Cancer
Women's Cancer Study Group GmbH 380
Not applicableActive Not RecruitingNCT07493525
What this trial is testing

Fall Frequency and Factors Affecting Dynamic Balance in Patients With Myotonic Dystrophy Type 1

Who this might be right for
Myotonic Dystrophy Type 1Falls
Antalya Training and Research Hospital 41
Not applicableStudy completedNCT05560438
What this trial is testing

Technology Assisted Rehabilitation for Upper Limb Function in Myotonic Dystrophy Type 1

Who this might be right for
Myotonic Dystrophy Type 1 (DM1)
University of Oslo 6
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