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Results for “DMMR Colorectal Cancer”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Not Yet RecruitingNCT07740720
What this trial is testing

The Duration of Dostarlimab in Untreated Mismatch Repair Deficient (dMMR)/ Microsatellite Instability-high (MSI-H) Locally Advanced Rectal Cancer

Who this might be right for
Neoplasms, Rectal
GlaxoSmithKline 90
Not applicableNot Yet RecruitingNCT07656740
What this trial is testing

Non-Operative Management and Following Immunotherapy for Colorectal Cancer and Other GI Cancers

Who this might be right for
Gastrointestinal CancerColorectal (Colon or Rectal) CancerStomach (Gastric) Cancer
Peking University Cancer Hospital & Institute 50
Not applicableStudy completedNCT04482608
What this trial is testing

The mCRC Patients With pMMR/MSS or dMMR/MSI-H Status Received Palliative Chemotherapy Efficacy and Survival

Who this might be right for
Colorectal Cancer MetastaticMismatch Repair DeficiencyMicrosatellite Instability High
Sun Yat-sen University 671
Testing effectiveness (Phase 2)UnknownNCT04636008
What this trial is testing

Sintilimab Plus Hypofractionated Radiotherapy for MSI-H/dMMR Rectal Cancer

Who this might be right for
Anti-PD-1 AntibodyRadiotherapyRectal Cancer+2 more
West China Hospital 20
Early research (Phase 1)Ended earlyNCT02952989
What this trial is testing

A Safety Study of SGN-2FF for Patients With Advanced Solid Tumors

Who this might be right for
Carcinoma, Non-Small-Cell LungCarcinoma, Renal CellBreast Neoplasms+5 more
Seagen Inc. 47
Large-scale testing (Phase 3)Active Not RecruitingNCT05652894
What this trial is testing

HX008 Compared to Chemotherapy in the First-Line Treatment of Subjects With MSI-H/dMMR Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Taizhou Hanzhong biomedical co. LTD 190
Testing effectiveness (Phase 2)Active Not RecruitingNCT05961709
What this trial is testing

The Phoenix Trial: Phase II Trial of Cemiplimab for the Non-operative Management of Localized dMMR Colon Cancer

Who this might be right for
Colon Cancer
M.D. Anderson Cancer Center 50
Large-scale testing (Phase 3)Study completedNCT02563002
What this trial is testing

Study of Pembrolizumab (MK-3475) vs Standard Therapy in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Carcinoma (MK-3475-177/KEYNOTE-177)

Who this might be right for
Colorectal Carcinoma
Merck Sharp & Dohme LLC 307
Not applicableStudy completedNCT06980350
What this trial is testing

Proposal of a Novel Model for Identifying Complete Response in dMMR Colon Cancer Following Neoadjuvant Immunotherapy

Who this might be right for
Colorectal Cancer
Sun Yat-sen University 156
Testing effectiveness (Phase 2)Active Not RecruitingNCT04802876
What this trial is testing

Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors

Who this might be right for
MSI-H Colorectal CancerMelanomaAnal Carcinoma+28 more
SOLTI Breast Cancer Research Group 184
Early research (Phase 1)Ended earlyNCT04244552
What this trial is testing

A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies

Who this might be right for
Breast CancerColorectal CancerOvarian Cancer+13 more
Atreca, Inc. 87
Testing effectiveness (Phase 2)Active Not RecruitingNCT06640049
What this trial is testing

Dostarlimab in Participants With Untreated Locally Advanced Rectal Cancer in China

Who this might be right for
Neoplasms, Rectal
GlaxoSmithKline 23
Testing effectiveness (Phase 2)UnknownNCT05429866
What this trial is testing

Immunological Variables Associated to ICI Toxicity in Cancer Patients

Who this might be right for
Breast CancerMelanomaNon Small Cell Lung Cancer+10 more
Jules Bordet Institute 441
Not applicableLooking for participantsNCT04643041
What this trial is testing

Watch and Wait in PD-1 Monoclonal Antibody Treated dMMR/MSI-H Distal Rectal Cancer

Who this might be right for
Rectal Cancer
Sixth Affiliated Hospital, Sun Yat-sen University 47
Not applicableStudy completedNCT05871567
What this trial is testing

Predictive Value of DNA Mismatch Repair System in Colorectal Cancers

Who this might be right for
MSI-H Colorectal Cancer
University of Campania Luigi Vanvitelli 403
Testing effectiveness (Phase 2)Looking for participantsNCT04014530
What this trial is testing

Pembrolizumab With Ataluren in Patients With Metastatic pMMR and dMMR Colorectal Carcinoma or Metastatic dMMR Endometrial Carcinoma: the ATAPEMBRO Study

Who this might be right for
Colorectal CancerEndometrium Cancer
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 47
Testing effectiveness (Phase 2)Looking for participantsNCT07262619
What this trial is testing

EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors

Who this might be right for
Advanced Solid TumorsMSI-H or dMMR Advanced Solid TumorsMSI-H/dMMR Gastric Cancer+4 more
Eikon Therapeutics 160
Testing effectiveness (Phase 2)Active Not RecruitingNCT03350126
What this trial is testing

IRECIST Evaluation's Relevance for DCR in MMR/MSI Metastatic Colorectal Cancer Patients on Nivolumab and Ipilimumab

Who this might be right for
Metastatic Cancer Colorectal
GERCOR - Multidisciplinary Oncology Cooperative Group 57
Testing effectiveness (Phase 2)Looking for participantsNCT05272709
What this trial is testing

TT-702 in Patients With Advanced Solid Tumours.

Who this might be right for
Advanced Solid Tumors
Cancer Research UK 60
Not applicableNot Yet RecruitingNCT07780305
What this trial is testing

ABCSG R07 Rectal Cancer Registry

Who this might be right for
Rectal CancerAdenocarcinoma of Rectum
Austrian Breast & Colorectal Cancer Study Group 600
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