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Results for “DNA Mutations”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Study completedNCT05162768
What this trial is testing

Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD)

Who this might be right for
Mitochondrial MyopathiesMitochondrial PathologyMitochondrial DNA Mutation+5 more
Stealth BioTherapeutics Inc. 102
Testing effectiveness (Phase 2)Ended earlyNCT01028716
What this trial is testing

Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Who this might be right for
Acute Biphenotypic LeukemiaAcute Erythroid Leukemia in RemissionAcute Leukemia in Remission+27 more
Fred Hutchinson Cancer Center 46
Large-scale testing (Phase 3)Study completedNCT02883049
What this trial is testing

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations

Who this might be right for
B Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia, BCR-ABL1-LikeCentral Nervous System Leukemia+1 more
National Cancer Institute (NCI) 5,949
Not applicableWithdrawnNCT00477932
What this trial is testing

Genes Mutation Pentalogy of Cantrell

Who this might be right for
Pentalogy of CantrellMutations in Non-muscle Genes
Children's Healthcare of Atlanta
Not applicableStudy completedNCT02322385
What this trial is testing

Clinical Implications of DNA Analysis on ADPKD

Who this might be right for
Autosomal Dominant Polycystic Kidney Disease
Kyorin University 80
Not applicableStudy completedNCT03562819
What this trial is testing

Study to Evaluate Concordance of Detecting EGFR (Epidermal Growth Factor Receptor) Mutation by Circulating Tumour Free DNA Versus Tissues Biopsy in NSCLC (Non-small Cell Lung Cancer).

Who this might be right for
NSCLC (Non-small Cell Lung Cancer)
AstraZeneca 268
Not applicableStudy completedNCT06490510
What this trial is testing

Prognostic Significance of Mutation Type and Chromosome Fragility in Fanconi Anemia

Who this might be right for
Fanconi Anemia
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau 227
Early research (Phase 1)Study completedNCT03056209
What this trial is testing

Safety, Tolerability and Pharmacokinetic Study of KL1333 in Healthy Male Volunteers

Who this might be right for
MELAS SyndromeMitochondrial Respiratory Chain Deficiencies
Yungjin Pharm. Co., Ltd. 60
Early research (Phase 1)Not Yet RecruitingNCT06614751
What this trial is testing

A PARG Inhibitor DAT-2645 Monotherapy in Patients with Advanced/Metastatic Solid Tumors Harboring BRCA1/2 Loss of Function Alterations And/or Other Defects in the DDR Pathway

Who this might be right for
Solid CancersBRCA MutationHRD Cancer+8 more
Danatlas Pharmaceuticals Co., Ltd 112
Not applicableLooking for participantsNCT05129605
What this trial is testing

Prostate Cancer Genetic Risk Evaluation and Screening Study

Who this might be right for
Prostatic NeoplasmProstate CancerBRCA2 Mutation+5 more
Massachusetts General Hospital 400
Not applicableStudy completedNCT04448158
What this trial is testing

Dynamics of Drug Resistance-associated Mutations in HIV-1 DNA Reverse Transcriptase Clearance During Effective Antiretroviral Therapy

Who this might be right for
HIV-1-infection
Association de Recherche en Virologie et Dermatologie 79
Testing effectiveness (Phase 2)Active Not RecruitingNCT03330847
What this trial is testing

To Assess Safety and Efficacy of Agents Targeting DNA Damage Repair With Olaparib Versus Olaparib Monotherapy.

Who this might be right for
Metastatic Triple Negative Breast Cancer
AstraZeneca 273
Not applicableStudy completedNCT02075307
What this trial is testing

Effect of Blueberry Consumption on Metabolic Syndrome & DNA Damage

Who this might be right for
Metabolic SyndromeInsulin ResistanceDNA Damage
UCSF Benioff Children's Hospital Oakland 7
Not applicableLooking for participantsNCT02705846
What this trial is testing

Analysing Outcomes After Prostate Cancer Diagnosis and Treatment in Carriers of Rare Germline Mutations

Who this might be right for
Prostate Cancer
Institute of Cancer Research, United Kingdom 4,260
Not applicableLooking for participantsNCT04541654
What this trial is testing

Li-Fraumeni & TP53 (LiFT UP): Understanding and Progress

Who this might be right for
Li-Fraumeni SyndromeTP53 Gene MutationHereditary Cancer Syndrome+2 more
Dana-Farber Cancer Institute 1,500
Not applicableStudy completedNCT02626039
What this trial is testing

Characterization & Comparison of Drugable Mutations in Primary and Metastatic Tumors, CTCs and cfDNA in MBCpatients

Who this might be right for
Metastatic Breast Cancer
Hospital General Universitario Gregorio Marañon 40
Not applicableUnknownNCT05814224
What this trial is testing

Monitoring luminAl Breast Cancer Through the Evaluation of Mutational and epiGeNEtic alteraTIons of Circulating ESR1 DNA

Who this might be right for
Hormone Receptor Positive Breast CarcinomaBreast NeoplasmsNeoplasms, Breast+4 more
Centro di Riferimento Oncologico - Aviano 164
Not applicableNot Yet RecruitingNCT06433570
What this trial is testing

Detection of Krupple Like Factor -1(KLF1/ EKLF) DNA Mutations in Beta Thalassemia Patients

Who this might be right for
EKLF Mutations in Beta Thalassemia Patients
Assiut University 100
Testing effectiveness (Phase 2)UnknownNCT02811354
What this trial is testing

Phase II Study of AZD9291 in Advanced Stage NSCLC With EGFR and T790M Mutations Detected in Plasma Ct-DNA

Who this might be right for
Carcinoma, Non-Small-Cell Lung
National University Hospital, Singapore 108
Not applicableStudy completedNCT03750175
What this trial is testing

OPTImal PALliative Anti-epidermal Growth Factor Receptor Treatment in Metastatic Colorectal Cancer -

Who this might be right for
Colorectal Cancer MetastaticCirculating Tumor DNAKRAS Gene Mutation+3 more
Karen-Lise Garm Spindler 49
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