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Results for “DNA Repair Disorder”

486 trials

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Showing 20 of 486 results

Not applicableStudy completedNCT00339859
What this trial is testing

DNA Repair, p53 and Apoptosis Phenotypes in Lung Cancer

Who this might be right for
Lung Neoplasms
National Cancer Institute (NCI) 5,625
Very early researchStudy completedNCT03832985
What this trial is testing

Pediatric Reporting of Adult-Onset Genomic Results

Who this might be right for
Hereditary Breast and Ovarian Cancer SyndromeLynch SyndromeFamilial Hypercholesterolemia
Geisinger Clinic 162
Not applicableStudy completedNCT03460483
What this trial is testing

Universal Endometrial Cancer DNA Sequencing for Detection of Lynch Syndrome and Personalized Care

Who this might be right for
Endometrial AdenocarcinomaEndometrial CarcinomaLynch Syndrome+1 more
Ohio State University Comprehensive Cancer Center 1,001
Not applicableLooking for participantsNCT07450612
What this trial is testing

Liquid Biopsy and Machine Learning for Early Colorectal Cancer, Adenomas, Lynch Cancers, and Residual Disease Detection

Who this might be right for
Colorectal CancerAdenoma ColonAdenoma Colon Polyp+16 more
San Raffaele University 1,200
Not applicableLooking for participantsNCT07498829
What this trial is testing

Population Based Germline Testing for Early Detection and Prevention of Cancer

Who this might be right for
Breast Cancer RiskOvarian Cancer RiskCancer Gene Mutation
Queen Mary University of London 6,000
Not applicableUnknownNCT01123694
What this trial is testing

Xeroderma Pigmentosum Patient Experiences

Who this might be right for
Xeroderma Pigmentosum
Henry Ford Health System 15
Not applicableUnknownNCT04605523
What this trial is testing

Neurofilament Light- Chain in Ataxia Telangiectasia

Who this might be right for
Ataxia Telangiectasia
Johann Wolfgang Goethe University Hospital 40
Testing effectiveness (Phase 2)Ended earlyNCT03875313
What this trial is testing

Study of CB-839 (Telaglenastat) in Combination With Talazoparib in Patients With Solid Tumors

Who this might be right for
Solid TumorClear Cell Renal Cell CarcinomaTNBC - Triple-Negative Breast Cancer+4 more
Calithera Biosciences, Inc 33
Testing effectiveness (Phase 2)Looking for participantsNCT03538899
What this trial is testing

Autologous Gene Therapy for Artemis-Deficient SCID

Who this might be right for
Severe Combined Immunodeficiency
University of California, San Francisco 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT03935893
What this trial is testing

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

Who this might be right for
Gastric CancerColorectal CancerPancreatic Cancer+7 more
Udai Kammula 20
Not applicableStudy completedNCT01216930
What this trial is testing

Molecular Screening for Lynch Syndrome in Southern Denmark

Who this might be right for
Colorectal CancerLynch SyndromeHNPCC
Vejle Hospital 2,000
Not applicableAvailableNCT07380165
What this trial is testing

Expanded Access Program (EAP) of Levacetylleucine for Ataxia-Telangiectasia (A-T)

Who this might be right for
Ataxia-Telangiectasia (A-T)
IntraBio Inc
Testing effectiveness (Phase 2)Active Not RecruitingNCT03924401
What this trial is testing

Acute GVHD Suppression Using Costimulation Blockade to Expand Non-malignant Transplant

Who this might be right for
Graft Versus Host Disease
Emory University 30
Not applicableNot Yet RecruitingNCT07201012
What this trial is testing

Determining the Prevalence of Muir-Torre Syndrome in Patients With Lynch Syndrome

Who this might be right for
Basal Cell Carcinoma of Skin, Site UnspecifiedEpidermoid CarcinomaLynch Syndrome+1 more
Centre Hospitalier Universitaire de Nīmes 150
Not applicableUnknownNCT04865601
What this trial is testing

DNA Adductomics for Colorectal Cancer Investigation

Who this might be right for
Colorectal CancerFamilial Adenomatous PolyposisHereditary Non-polyposis Colon Cancer+1 more
University of Copenhagen 60
Testing effectiveness (Phase 2)WithdrawnNCT04370795
What this trial is testing

Matched Related and Unrelated Donor Stem Cell Transplantation for Severe Combined Immune Deficiency (SCID): Busulfan-based Conditioning With h-ATG, Radiation, and Sirolimus

Who this might be right for
Severe Combined Immune Deficiency (SCID)
National Institute of Allergy and Infectious Diseases (NIAID)
Post-approval studies (Phase 4)UnknownNCT01052623
What this trial is testing

Status of Growth Hormone/ Insulin-like Growth Factor-1 (GH/IGF-1) Axis and Growth Failure in Ataxia Telangiectasia (AT)

Who this might be right for
Ataxia TelangiectasiaGrowth Failure
Johann Wolfgang Goethe University Hospital 24
Not applicableEnded earlyNCT00985413
What this trial is testing

Observational Study to Assess Natural History in Cockayne Syndrome Patients

Who this might be right for
Cockayne Syndrome
DNage B.V. 40
Not applicableNot Yet RecruitingNCT06501417
What this trial is testing

EC_ItaLynch: Mainstreaming the Diagnosis of Lynch Syndrome

Who this might be right for
Lynch SyndromeEndometrial Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 600
Testing effectiveness (Phase 2)Ended earlyNCT02203513
What this trial is testing

A Phase II Single Arm Pilot Study of the Chk1/2 Inhibitor (LY2606368) in BRCA1/2 Mutation Associated Breast or Ovarian Cancer, Triple Negative Breast Cancer, High Grade Serous Ovarian Cancer, and Metastatic Castrate-Resistant Prostate Cancer

Who this might be right for
Ovarian CancerBreast CancerProstate Cancer
National Cancer Institute (NCI) 111
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