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Results for “DNA Repair Disorder”

481 trials

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Showing 20 of 481 results

Not applicableLooking for participantsNCT00055172
What this trial is testing

Genetic Basis of Immunodeficiency

Who this might be right for
Severe Combined Immunodeficiency
National Heart, Lung, and Blood Institute (NHLBI) 100
Not applicableStudy completedNCT00005892
What this trial is testing

Study of Allogeneic Bone Marrow Transplantation Following Cyclophosphamide and Radiotherapy in Patients With Myelodysplastic Syndrome and Acute Leukemia Related to Fanconi's Anemia

Who this might be right for
Fanconi's AnemiaMyelodysplastic SyndromesLeukemia, Nonlymphocytic, Acute+1 more
Fairview University Medical Center
Early research (Phase 1)Looking for participantsNCT06487481
What this trial is testing

Study of Preoperative Radiation Therapy in Participants With Resectable Recurrent Abdominal Adrenocortical Carcinoma

Who this might be right for
Adrenocortical Carcinoma (ACC)Recurrent Adrenocortical Carcinoma (ACC)Recurrent Abdominal Adrenocortical Carcinoma (ACC)+2 more
National Cancer Institute (NCI) 32
Not applicableLooking for participantsNCT05495776
What this trial is testing

Prospective Multicenter Registry Study to Assess the Frequency of Lynch Syndrome Among Patients With Colorectal Cancer

Who this might be right for
Colorectal CancerLynch SyndromeHereditary Colorectal Cancer+1 more
State Scientific Centre of Coloproctology, Russian Federation 2,500
Testing effectiveness (Phase 2)Study completedNCT03207347
What this trial is testing

A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001)

Who this might be right for
MesotheliomaUveal MelanomaRenal Cell Carcinoma+1 more
University of Florida 37
Not applicableStudy completedNCT01646112
What this trial is testing

Uncertain Genetic Test Results for Lynch Syndrome

Who this might be right for
HNPCC
National Human Genome Research Institute (NHGRI) 27
Testing effectiveness (Phase 2)Looking for participantsNCT07371663
What this trial is testing

An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors

Who this might be right for
Solid CancersNSCLC (Advanced Non-small Cell Lung Cancer)Gastric (Stomach) Cancer+2 more
Beijing Tide Pharmaceutical Co., Ltd 266
Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Testing effectiveness (Phase 2)Study completedNCT03519412
What this trial is testing

Pembrolizumab in MMR-Proficient Metastatic Colorectal Cancer Pharmacologically Primed to Trigger Hypermutation Status

Who this might be right for
Colorectal NeoplasmsMicrosatellite Instability
IFOM ETS - The AIRC Institute of Molecular Oncology 107
Testing effectiveness (Phase 2)Active Not RecruitingNCT03344965
What this trial is testing

Olaparib In Metastatic Breast Cancer

Who this might be right for
Metastatic Breast CancerInvasive Breast CancerSomatic Mutation Breast Cancer (BRCA1)+7 more
Beth Israel Deaconess Medical Center 114
Testing effectiveness (Phase 2)Looking for participantsNCT04550494
What this trial is testing

Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Castration-Resistant Prostate Carcinoma+28 more
National Cancer Institute (NCI) 36
Not applicableStudy completedNCT01823471
What this trial is testing

I-Scan For Colon Polyp Detection In HNPCC

Who this might be right for
Hereditary Non-polyposis Colon CarcinomaHNPCCLynch Syndrome
Universitaire Ziekenhuizen KU Leuven 70
Early research (Phase 1)UnknownNCT05531890
What this trial is testing

Comparative Bioavailability of Betamethasone Oral Solution Metered Spray (GTX-102) in Healthy Subjects

Who this might be right for
Ataxia Telangiectasia
Grace Therapeutics Inc. 48
Not applicableStudy completedNCT00313755
What this trial is testing

Magnification Narrow Band Imaging Colonoscopy for Hereditary Non-Polyposis Colorectal Cancer Surveillance

Who this might be right for
Colorectal Neoplasms, Hereditary Nonpolyposis
London North West Healthcare NHS Trust 60
Testing effectiveness (Phase 2)Ended earlyNCT04155190
What this trial is testing

Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas in Patients With Non-Gorlin High Frequency BCC

Who this might be right for
Recurrent Basal Cell Carcinoma
Sol-Gel Technologies, Ltd. 47
Not applicableStudy completedNCT00001255
What this trial is testing

Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency: A Natural History Study

Who this might be right for
Severe Combined Immunodeficiency
National Human Genome Research Institute (NHGRI) 10
Testing effectiveness (Phase 2)Study completedNCT00479115
What this trial is testing

Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and AMD3100

Who this might be right for
Fanconi Anemia
Children's Hospital Medical Center, Cincinnati 1
Not applicableUnknownNCT03294343
What this trial is testing

Risk-Reducing Surgeries for Hereditary Ovarian Cancer

Who this might be right for
Hereditary Breast and Ovarian Cancer SyndromeColorectal Neoplasms, Hereditary NonpolyposisOvariectomy+1 more
Lei Li 600
Not applicableUnknownNCT04453267
What this trial is testing

DNA Repair in Patients With Stable Angina.

Who this might be right for
Coronary Artery DiseaseCoronary ArteriosclerosisDNA Damage+1 more
University Hospital Southampton NHS Foundation Trust 172
Not applicableStudy completedNCT00043225
What this trial is testing

The Role of Bacteria and Genetic Variations in Cystic Fibrosis

Who this might be right for
Psuedomas InfectionCystic Fibrosis
National Heart, Lung, and Blood Institute (NHLBI) 76
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