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Results for “DPD Deficiency”

7 trials

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Showing 7 of 7 results

Testing effectiveness (Phase 2)Study completedNCT06782022
What this trial is testing

DPD Guided 5-FU Precision Treatment in Gastro-intestinal Cancer Patients

Who this might be right for
Gastrointestinal Cancers
Jan Gerard Maring 80
Not applicableEnded earlyNCT01547923
What this trial is testing

Pre-therapeutic Identification of Dihydropyrimidine Dehydrogenase Gene (DPD) Deficiency for Predicting Toxicity to Fluoropyrimidines

Who this might be right for
Colorectal CancerIntravenous 5 Fluorouracile
Institut Cancerologie de l'Ouest 1,142
Testing effectiveness (Phase 2)Looking for participantsNCT06245356
What this trial is testing

Safety of Trifluridine/Tipiracil in Patients With Dihydropyrimidine Dehydrogenase Deficiency Diagnosed With Metastatic Colorectal or Gastroesophageal Cancer

Who this might be right for
Metastatic Colorectal CancerMetastatic Gastroesophageal AdenocarcinomaDPD Deficiency
UNICANCER 73
Not applicableTemporarily pausedNCT04541381
What this trial is testing

The PhOCus Trial: Implementation of Pharmacogenomic Testing in Oncology Care

Who this might be right for
Gastrointestinal CancerHead and Neck CancerDihydropyrimidine Dehydrogenase Deficiency+2 more
University of Chicago 860
Not applicableStudy completedNCT00953537
What this trial is testing

Predicting Response to Capecitabine in Women With Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Centre Antoine Lacassagne 303
Not applicableLooking for participantsNCT06092346
What this trial is testing

A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders

Who this might be right for
AMPD3, OMIM*102772, AMP Deaminase DeficiencyAK1, OMIM *103000, Adenylate Kinase DeficiencyAMPD1, OMIM *102770, Myopathy Due to Myoadenylate Deaminase Deficiency+25 more
National Human Genome Research Institute (NHGRI)
Testing effectiveness (Phase 2)Looking for participantsNCT06475352
What this trial is testing

Dose Individualization of Chemotherapy in Patients With Gastrointestinal Cancers Lacking a Specific Liver Enzyme

Who this might be right for
Digestive CancerColorectal Cancer
UNICANCER 400
999