Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Dementia Severe”

170 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 170 results

Not applicableStudy completedNCT00570583
What this trial is testing

Neurocognitive Outcomes of Depression in the Elderly

Who this might be right for
Major DepressionDementia
Duke University 795
Not applicableLooking for participantsNCT07402356
What this trial is testing

VR Pupillometry in Cognitive Impairment

Who this might be right for
Alzheimer s DiseaseMajor Depressive Disorder (MDD)Mild Cognitive Impairment+1 more
Max-Planck-Institute of Psychiatry 140
Not applicableLooking for participantsNCT06539169
What this trial is testing

FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases

Who this might be right for
Alpha-ThalassemiaBeta-ThalassemiaAmyloidosis+14 more
xCures 1,000
Not applicableNot Yet RecruitingNCT06559254
What this trial is testing

TDCS as Augmentation Therapy to Cognitive Training in Mild Dementia

Who this might be right for
Major Neurocognitive Disorder
Hospital Authority, Hong Kong 36
Large-scale testing (Phase 3)Study completedNCT01404169
What this trial is testing

A 24-weeks, Multi-center, Randomized, Double-blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of Donepezil Hydrochloride in Chinese Subjects With Severe Alzheimer's Disease

Who this might be right for
Alzheimer's Type Dementia
Eisai Limited 260
Not applicableTemporarily pausedNCT04178564
What this trial is testing

Major Memory 2: A Long-term Group Cognitive Stimulation Program

Who this might be right for
Neurocognitive DisordersDementiaCognitive Impairment+1 more
Rsocialform - Geriatria, Lda 70
Not applicableStudy completedNCT04949984
What this trial is testing

Bright Light Therapy in Older Adults With Moderate to Very Severe Dementia

Who this might be right for
DementiaMoodBehavior
Universidade da Coruña 39
Not applicableNot Yet RecruitingNCT07200739
What this trial is testing

Speech-Based Artificial Intelligence for Detection of Dementia in Danish Patients (DetectAI)

Who this might be right for
Dementia (Diagnosis)Alzheimer Dementia (AD)Vascular Dementia (VaD)+6 more
Zealand University Hospital 440
Post-approval studies (Phase 4)Study completedNCT05531591
What this trial is testing

RCT of Brain Longitudinal Biomarker Study (OPT-Neuro RCT)

Who this might be right for
DepressionDementiaMild Cognitive Impairment+5 more
Centre for Addiction and Mental Health 87
Not applicableStudy completedNCT02761707
What this trial is testing

Biomarkers in Neural Disorders

Who this might be right for
Parkinson's DiseaseAlzheimer's DiseaseProgressive Supranuclear Palsy+6 more
University of Pennsylvania 54
Not applicableUnknownNCT05474872
What this trial is testing

Postoperative Delirium in the ICU Setting of an Eastern European Centre

Who this might be right for
Postoperative DeliriumCognitive Impairment
Institutul Regional de Gastroenterologie & Hepatologie Prof. dr. Octavian Fodor 100
Post-approval studies (Phase 4)Study completedNCT02203019
What this trial is testing

Study of Sedative Medications in Patients With Severe Infection and Respiratory Failure

Who this might be right for
SepsisRespiratory FailureAgitation
Texas Tech University Health Sciences Center 36
Early research (Phase 1)Study completedNCT05273320
What this trial is testing

Clinical Trial of Nabilone for Aggression in Adults With Intellectual and Developmental Disabilities

Who this might be right for
Intellectual DisabilityDevelopmental DisabilityAggression+1 more
Hsiang-Yuan Lin 20
Not applicableStudy completedNCT01747824
What this trial is testing

Stress Biomarkers Among Patients Undergoing Treatment for Excited Delirium and Severe Pain in the Emergency Department

Who this might be right for
AgitationExcited DeliriumPain
Hennepin Healthcare Research Institute 1,322
Large-scale testing (Phase 3)Ended earlyNCT00679627
What this trial is testing

Galantamine Used to Treat Patients With Mild to Moderate Alzheimer's Disease

Who this might be right for
Alzheimer's Disease
Janssen Research & Development, LLC 2,051
Not applicableUnknownNCT05048966
What this trial is testing

Comparison of Two Group Wellness Interventions for Individuals With Neurologic Conditions and Their Support Persons

Who this might be right for
Traumatic Brain InjuryMild Traumatic Brain InjuryAlzheimer's Disease+3 more
Kessler Foundation 360
Post-approval studies (Phase 4)Study completedNCT00401167
What this trial is testing

Memantine for Agitation and Aggression in Severe Alzheimer's Disease

Who this might be right for
Alzheimer's Disease
Sunnybrook Health Sciences Centre 31
Testing effectiveness (Phase 2)Looking for participantsNCT06745583
What this trial is testing

Assess the Safety of EI-1071 and the Effects of EI-1071 on Neuroinflammation in Alzheimer's Disease Patients

Who this might be right for
Mild, Moderate, or Severe Alzheimer's Disease
Elixiron Immunotherapeutics Inc. 15
Not applicableUnknownNCT05658666
What this trial is testing

Video Feedback Intervention in Nursing Home Residents With Dementia and Severe Challenging Behavior.

Who this might be right for
DementiaNursing Home ResidentChallenging Behavior
Radboud University Medical Center 25
Post-approval studies (Phase 4)UnknownNCT05430867
What this trial is testing

Efficacy and Safety of Memantine and Sodium Oligomannate in Patients With Moderate to Severe Alzheimer's Disease

Who this might be right for
TreatmentEfficacySafety+1 more
First Affiliated Hospital Xi'an Jiaotong University 150
Load More Results