Testing effectiveness (Phase 2)Active Not RecruitingNCT05676034What this trial is testingAMX0035 in Adult Patients With Wolfram SyndromeWho this might be right forWolfram Syndrome Amylyx Pharmaceuticals Inc. 12
Testing effectiveness (Phase 2)UnknownNCT05659368What this trial is testingTirzepatide Monotherapy in Patients With Wolfram Syndrome Type 1Who this might be right forWolfram Syndrome Ospedale San Raffaele 10
Early research (Phase 1)Looking for participantsNCT04789148What this trial is testingEffects of Intranasal Oxytocin in Patients With Arginine-vasopressin DeficiencyWho this might be right forVasopressin Deficiency Elizabeth Austen Lawson 40
Testing effectiveness (Phase 2)UnknownNCT04940572What this trial is testingEfficacy Study of Daily Administration of VPA in Patients Affected by Wolfram SyndromeWho this might be right forWolfram Syndrome Centre d'Etude des Cellules Souches 23
Not applicableLooking for participantsNCT06789705What this trial is testingPlasma Oxytocin Changes in Response to Low-dose MDMA vs. Placebo in Patients With Arginine Vasopressin Deficiency and Healthy ControlsWho this might be right forCentral Diabetes Insipidus University Hospital, Basel, Switzerland 24
Not applicableLooking for participantsNCT07569861What this trial is testingCopeptin Measurement After Mannitol and Hypertonic Saline for the Diagnosis of Polyuria-polydipsia SyndromeWho this might be right forArginine Vasopressin DeficiencyPrimary Polydipsia University Hospital, Basel, Switzerland 144
Not applicableStudy completedNCT00004363What this trial is testingStudy of the Pathogenesis and Pathophysiology of Familial Neurohypophyseal Diabetes InsipidusWho this might be right forDiabetes InsipidusDiabetes Insipidus, Neurohypophyseal National Center for Research Resources (NCRR)
Testing effectiveness (Phase 2)Looking for participantsNCT06808516What this trial is testingEffects of Intranasal Oxytocin on Sexual Well-Being in Patients With Arginine Vasopressin Deficiency and Healthy ControlsWho this might be right forArginine Vasopressin DeficiencyCentral Diabetes InsipidusOxytocin Deficiency University Hospital, Basel, Switzerland 42
Large-scale testing (Phase 3)Study completedNCT01280188What this trial is testingMinirin Melt in Japanese Patients With Central Diabetes Insipidus (CDI).Who this might be right forCentral Diabetes Insipidus Ferring Pharmaceuticals 20
Testing effectiveness (Phase 2)Study completedNCT03497806What this trial is testingOpen-Label Extension of CP101 Trials Evaluating Oral Full-Spectrum Microbiota™ (CP101) in Subjects With Recurrence of Clostridium Difficile InfectionWho this might be right forClostridium Difficile InfectionRecurrent Clostridium Difficile InfectionC. Diff+8 more Finch Research and Development LLC. 132
Not applicableStudy completedNCT02455414What this trial is testingTracking Neurodegeneration in Early Wolfram SyndromeWho this might be right forType 1 DiabetesDiabetes InsipidusDiabetes Mellitus+1 more Washington University School of Medicine 101
Not applicableStudy completedNCT06542198What this trial is testingMannitol-induced Release of Copeptin in Healthy Adults and Patients With Polyuria-Polydipsia Syndrome (MARS Study)Who this might be right forPolyuria-polydipsia SyndromeArginine Vasopressin DeficiencyPrimary Polydipsia University Hospital, Basel, Switzerland 42
Not applicableStudy completedNCT01107314What this trial is testingVasopressin Deficiency in Hemorrhagic ShockWho this might be right forBody Response to Trauma The University of Texas Health Science Center at San Antonio 81
Very early researchStudy completedNCT06460948What this trial is testingIdentifying Oxytocin Deficiency in Adults With Pituitary DiseaseWho this might be right forArginine Vasopressin DeficiencyOxytocin Deficiency Elizabeth Austen Lawson 28
Not applicableLooking for participantsNCT03988764What this trial is testingMonogenic Diabetes Misdiagnosed as Type 1Who this might be right forDiabetes Mellitus, Type 1Monogenic DiabetesNeonatal Diabetes+4 more McGill University Health Centre/Research Institute of the McGill University Health Centre 5,000
Post-approval studies (Phase 4)Study completedNCT04902235What this trial is testingIdentification and Clinical Relevance of an Oxytocin Deficient State (CRH Study)Who this might be right forHypopituitarismCentral Diabetes InsipidusPanhypopituitarism+5 more Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau 52
Testing effectiveness (Phase 2)Study completedNCT02829268What this trial is testingA Clinical Trial of Dantrolene Sodium in Pediatric and Adult Patients With Wolfram SyndromeWho this might be right forWolfram SyndromeDiabetes MellitusOptic Nerve Atrophy+1 more Washington University School of Medicine 21
Not applicableLooking for participantsNCT07276152What this trial is testingPlasma Oxytocin Changes in Response to Music Modified by Sonic Augmentation TechnologyWho this might be right forSonic Augmentation Technology University Hospital, Basel, Switzerland 22
Testing effectiveness (Phase 2)Study completedNCT03717909What this trial is testingEfficacy and Safety Trial of Sodium Valproate, in Paediatric and Adult Patients With Wolfram SyndromeWho this might be right forWolfram Syndrome University of Birmingham 63
Not applicableStudy completedNCT03951298What this trial is testingI-Tracking Neurodegeneration in Early Wolfram SyndromeWho this might be right forWolfram Syndrome Washington University School of Medicine 128