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Results for “Dose Escalation”

6,513 trials

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Showing 20 of 6,513 results

Early research (Phase 1)UnknownNCT04151407
What this trial is testing

The Study of Drug 601 in Patients With Diabetic Macular Edema (DME)

Who this might be right for
Diabetic Macular Edema
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. 50
Early research (Phase 1)Study completedNCT02316756
What this trial is testing

A Single Ascending Dose Study To Evaluate Safety And Pharmacokinetics Of Compound PF-06648671 In Healthy Subjects

Who this might be right for
Healthy Subjects
Pfizer 18
Early research (Phase 1)Study completedNCT02348372
What this trial is testing

Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Single Oral Doses of GSK1278863A in Healthy Subjects

Who this might be right for
Anaemia
GlaxoSmithKline 34
Early research (Phase 1)Study completedNCT02340572
What this trial is testing

First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PRS-080

Who this might be right for
Healthy
Pieris Pharmaceuticals GmbH 48
Early research (Phase 1)Study completedNCT01814839
What this trial is testing

A Phase 1, Single- and Multi-Dose, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered ALN-TTRSC (Revusiran) in Healthy Volunteers

Who this might be right for
TTR-mediated Amyloidosis
Alnylam Pharmaceuticals 85
Testing effectiveness (Phase 2)Study completedNCT02579239
What this trial is testing

Evaluate Safety and Biological Activity of ATYR1940 in Participants With Limb Girdle Muscular Dystrophy 2B (LGMD2B) and Facioscapulohumeral Muscular Dystrophy (FSHD)

Who this might be right for
Limb-Girdle Muscular DystrophiesFacioscapulohumeral Muscular Dystrophy
aTyr Pharma, Inc. 18
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07460375
What this trial is testing

Evaluate Claudin 18.2-Directed ADC LCB02A in Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
LigaChem Biosciences, Inc. 191
Early research (Phase 1)Looking for participantsNCT06547528
What this trial is testing

A Phase I Study to Investigate the Tolerability and Safety of ONO-4685 Given as Monotherapy in T Cell Lymphoma and CLL/SLL

Who this might be right for
Relapsed or Refractory T Cell Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Ono Pharmaceutical Co., Ltd. 108
Early research (Phase 1)Study completedNCT02171637
What this trial is testing

Dose Escalation Study of Oral Treatment With BIBW 2992 in Patients With Advanced Solid Tumors

Who this might be right for
Neoplasms
Boehringer Ingelheim 38
Testing effectiveness (Phase 2)Study completedNCT00729872
What this trial is testing

A Phase 2a Study to Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of AG011 in Ulcerative Colitis

Who this might be right for
Moderately Active Ulcerative Colitis
ActoGeniX N.V. 60
Post-approval studies (Phase 4)Study completedNCT04982172
What this trial is testing

Model-informed Dose De-escalation of Infliximab in Patients With Inflammatory Bowel Diseases

Who this might be right for
Inflammatory Bowel Diseases
Universitaire Ziekenhuizen KU Leuven 80
Early research (Phase 1)Study completedNCT03000257
What this trial is testing

Budigalimab (ABBV-181) in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
AbbVie 182
Early research (Phase 1)Ended earlyNCT02936102
What this trial is testing

FAZ053 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies.

Who this might be right for
Advanced Solid TumorsTriple Negative Breast CancerChordoma and Alveolar Soft Part Sarcoma
Novartis Pharmaceuticals 154
Early research (Phase 1)Study completedNCT03192345
What this trial is testing

A First-in-human Study of the Safety, Pharmacokinetics, Pharmacodynamics and Anti-tumor Activity of SAR439459 Monotherapy and Combination of SAR439459 and Cemiplimab in Patients With Advanced Solid Tumors

Who this might be right for
Malignant Solid Tumor
Sanofi 161
Large-scale testing (Phase 3)Study completedNCT00435045
What this trial is testing

Evaluation of Efficacy and Safety of Omacor, Co-Administered With Atorvastatin, in Subjects With Hypertriglyceridemia

Who this might be right for
Hypertriglyceridemia
GlaxoSmithKline 245
Testing effectiveness (Phase 2)Study completedNCT00721045
What this trial is testing

A Phase II Dose-escalation Study to Assess the Feasibility and Safety of Transendocardial Delivery of Three Different Doses of Allogeneic Mesenchymal Precursor Cells (MPCs)in Subjects With Heart Failure

Who this might be right for
Heart Failure
Mesoblast, Ltd. 60
Early research (Phase 1)UnknownNCT03130881
What this trial is testing

Phase I Study of a Selective ALK Inhibitor PLB1003 in Patients With ALK+ NSCLC.

Who this might be right for
Non-Small Cell Lung Cancer
Beijing Pearl Biotechnology Limited Liability Company 60
Testing effectiveness (Phase 2)Study completedNCT00951665
What this trial is testing

Trastuzumab Emtansine, Paclitaxel, and Pertuzumab in Patients With HER2-Positive, Locally Advanced or Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer
Genentech, Inc. 107
Early research (Phase 1)UnknownNCT05083000
What this trial is testing

Reducing Hypoxia in Patients With Coronavirus Disease (COVID-19) Using Topotecan With Standard of Care

Who this might be right for
COVID-19 Respiratory Infection
National University Hospital, Singapore 24
Testing effectiveness (Phase 2)Study completedNCT02387099
What this trial is testing

Dose EScalation Induction of EvERolimus

Who this might be right for
Breast CancerHormone Receptor Positive Tumor
GBG Forschungs GmbH 156
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