Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Dose Escalation”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Early research (Phase 1)Study completedNCT01195311
What this trial is testing

A Dose-escalation Study in Subjects With Advanced Malignancies

Who this might be right for
Solid Tumors and Hematologic Malignancy
Incyte Corporation 52
Early research (Phase 1)Looking for participantsNCT06673017
What this trial is testing

PTM-101 in Pancreatic Ductal Adenocarcinoma (PDAC)

Who this might be right for
Pancreatic Ductal AdenocarcinomaBorderline Resectable Pancreatic AdenocarcinomaLocally Advanced Pancreatic Adenocarcinoma+1 more
PanTher Therapeutics 26
Early research (Phase 1)Study completedNCT00922740
What this trial is testing

VA106483 Dose Response Study in Elderly Males

Who this might be right for
Nocturia
Vantia Ltd 10
Large-scale testing (Phase 3)Study completedNCT00326391
What this trial is testing

A Safety and Effectiveness Study of Methylphenidate HCl Extended-release Tablets in Adults With Attention Deficit Hyperactivity Disorder

Who this might be right for
Attention Deficit Disorder With Hyperactivity
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. 229
Early research (Phase 1)WithdrawnNCT05381935
What this trial is testing

ES014 (Anti-CD39/TGF-β Bispecific Antibody) in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumor
Elpiscience Biopharma, Ltd.
Early research (Phase 1)Study completedNCT01798108
What this trial is testing

Dose Escalation Study of Radium-223 Dichloride in Patients With Advanced Skeletal Metastases

Who this might be right for
Neoplasm Metastasis
Bayer 31
Testing effectiveness (Phase 2)Study completedNCT05284617
What this trial is testing

Exploratory Ph 2A, Double-Blind, Placebo-Controlled Dose Escalation Study of Safety, Tolerability, PD, & PK of HU6 for Subjects With Obese HFpEF

Who this might be right for
Heart Failure With Preserved Ejection Fraction
Rivus Pharmaceuticals, Inc. 67
Early research (Phase 1)Study completedNCT03630315
What this trial is testing

CLN-0046: Treatment of AMD Subjects With OTX-TKI

Who this might be right for
Neovascular Age-related Macular Degeneration
Ocular Therapeutix, Inc. 29
Early research (Phase 1)Looking for participantsNCT05629689
What this trial is testing

Evaluate GEH200520/GEH200521 (18F) Safety and Tolerability When Used for PET Scans in Patients With Solid Tumour Malignancies

Who this might be right for
Malignant Solid TumorOncology
GE Healthcare 50
Testing effectiveness (Phase 2)Study completedNCT06087289
What this trial is testing

Evaluate the Safety of KAND567, in Combination With Carboplatin Therapy, in Women With Recurrent Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Who this might be right for
Epithelial Ovarian CancerFallopian Tube CancerPeritoneal Cancer
Novakand Pharma AB 18
Testing effectiveness (Phase 2)Looking for participantsNCT07462650
What this trial is testing

Dual-Target CAR-NK Cells for Biomarker-Selected Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticAdenocarcinoma of Colon
Beijing Biotech 48
Early research (Phase 1)Study completedNCT02286817
What this trial is testing

Phase I Single Dose, Open-Label Pharmacokinetic Study and Single-Blind, Placebo-Controlled Dose Escalation Study of NFC-1 in Adolescents With Attention-Deficit Hyperactivity Disorder

Who this might be right for
Attention-deficit Hyperactivity Disorder (ADHD)
Aevi Genomic Medicine, LLC, a Cerecor company 30
Early research (Phase 1)Looking for participantsNCT07755397
What this trial is testing

First in Human Multicenter Open Name Dose-increase, Consolidation Method to Study Safety Drug-level in Blood & Drug Metabolism Clinical Activity of Oral JBI-778 in Lung Cancer Patients With, Without Brain Metastasis IDH Mutated WHO Grade 3,4 Recurrent Glioma, Salivary Glands Tumor

Who this might be right for
NSCLC Patients With EGFR Activating MutationAdenoid Cystic Carcinoma MetastaticAdenoid Cystic Carcinoma of the Head and Neck
Jubilant Therapeutics India Limited 30
Early research (Phase 1)Active Not RecruitingNCT04049513
What this trial is testing

ENABLE-1 (Engaging Toll-like Receptor Signalling for B-cell Lymphoma Chimeric Antigen Receptor Therapy)

Who this might be right for
Lymphomas Non-Hodgkin's B-CellDiffuse Large B-cell Lymphoma (DLBCL)Primary Mediastinal B-cell Lymphoma (PMBCL)+3 more
Malaghan Institute of Medical Research 30
Testing effectiveness (Phase 2)Looking for participantsNCT06515990
What this trial is testing

DM005 in Patients With Advanced Solid Tumors

Who this might be right for
Carcinoma, Non-Small-Cell LungSquamous Cell Carcinoma of Head and NeckSolid Carcinoma
Doma Biopharmaceutical（Suzhou）Co., Ltd. 208
Early research (Phase 1)Study completedNCT01878890
What this trial is testing

Phase I Dose Escalation Trial of Efavirenz in Solid Tumours or Non-Hodgkin Lymphoma in Therapeutic Failure.

Who this might be right for
Solid TumorsNon-Hodgkin's Lymphoma
Institut Bergonié 25
Early research (Phase 1)Study completedNCT02146313
What this trial is testing

A Study Evaluating the Safety and Pharmacokinetics of DMUC4064A in Participants With Platinum-Resistant Ovarian Cancer or Unresectable Pancreatic Cancer

Who this might be right for
Pancreatic NeoplasmsOvarian Neoplasms
Genentech, Inc. 35
Early research (Phase 1)Temporarily pausedNCT05076591
What this trial is testing

IMM2902, a HER2/SIRPα Bispecific MAb-Trap Antibody-receptor Fusion Protein, in Patients with HER2-expressing Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorAdvanced Breast CancerAdvanced Gastric Cancer
ImmuneOnco Biopharmaceuticals (Shanghai) Inc. 135
Early research (Phase 1)Study completedNCT05169697
What this trial is testing

Assess YH002 in Combination with YH001 in Subjects with Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Eucure (Beijing) Biopharma Co., Ltd 6
Early research (Phase 1)Study completedNCT00412997
What this trial is testing

LBH589 in Adult Patients With Advanced Solid Tumors or Cutaneous T-cell Lymphoma

Who this might be right for
TumorsCutaneous T-Cell Lymphoma
Novartis 14
Next Page