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Results for “Driver Mutation”

90 trials

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Showing 20 of 90 results

Not applicableStudy completedNCT06098690
What this trial is testing

Culturally Tailored HPV Psychoeducational Multimedia Intervention

Who this might be right for
Health Knowledge, Attitudes, PracticeVaccine-Preventable DiseasesIntention+1 more
University of Texas, El Paso 63
Testing effectiveness (Phase 2)Ended earlyNCT04171700
What this trial is testing

Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes

Who this might be right for
Solid Tumor
pharmaand GmbH 83
Testing effectiveness (Phase 2)Study completedNCT02282345
What this trial is testing

Talazoparib Before Standard Therapy in Treating Patients With Invasive, BRCA-Mutated Breast Cancer

Who this might be right for
Breast AdenocarcinomaDeleterious BRCA1 Gene MutationDeleterious BRCA2 Gene Mutation+2 more
M.D. Anderson Cancer Center 36
Testing effectiveness (Phase 2)Ended earlyNCT06478862
What this trial is testing

Promitil Treatment of Patients With Solid Tumors Associated With Deleterious Mutations Who Have Progressed After Therapy

Who this might be right for
Cancer of OvaryPancreatic Ductal Adenocarcinoma
Lipomedix Pharmaceuticals Inc. 19
Testing effectiveness (Phase 2)Study completedNCT06501378
What this trial is testing

Cranial Radiotherapy Plus Chemoimmunotherapy in Untreated Driver-mutation Negative NSCLC With Active Brain Metastasis

Who this might be right for
NSCLC Stage IV
Fudan University 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT03609216
What this trial is testing

Gemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic Alterations

Who this might be right for
Infiltrating Bladder Urothelial CarcinomaStage II Bladder Urothelial CarcinomaStage III Bladder Urothelial Carcinoma
Alliance for Clinical Trials in Oncology 237
Early research (Phase 1)Study completedNCT03586661
What this trial is testing

Niraparib and Copanlisib in Treating Patients With Recurrent Endometrial, Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Who this might be right for
Deleterious BRCA1 Gene MutationDeleterious BRCA2 Gene MutationEndometrial Adenocarcinoma+8 more
M.D. Anderson Cancer Center 31
Testing effectiveness (Phase 2)Ended earlyNCT03140670
What this trial is testing

Maintenance Rucaparib in BRCA1, BRCA2 or PALB2 Mutated Pancreatic Cancer That Has Not Progressed on Platinum-based Therapy

Who this might be right for
Pancreatic Cancer
Abramson Cancer Center at Penn Medicine 46
Testing effectiveness (Phase 2)Study completedNCT02789332
What this trial is testing

Assessing the Efficacy of Paclitaxel and Olaparib in Comparison to Paclitaxel / Carboplatin Followed by Epirubicin/Cyclophosphamide as Neoadjuvant Chemotherapy in Patients With HER2-negative Early Breast Cancer and Homologous Recombination Deficiency

Who this might be right for
Breast CancerTriple Negative Breast NeoplasmsHRpos Breast Neoplasms+1 more
GBG Forschungs GmbH 107
Not applicableLooking for participantsNCT04324151
What this trial is testing

Pembrolizumab Combined With Double Platinum Based Chemotherapy for Potentially Resectable NSCLC

Who this might be right for
Non Small Cell Lung Cancer
Hunan Province Tumor Hospital 70
Not applicableActive Not RecruitingNCT03546972
What this trial is testing

Diabetes Prevention Program With or Without Hunger Training in Helping to Lower Breast Cancer Risk in Obese Participants

Who this might be right for
Deleterious BRCA1 Gene MutationDeleterious BRCA2 Gene MutationDuctal Breast Carcinoma In Situ+3 more
M.D. Anderson Cancer Center 51
Testing effectiveness (Phase 2)UnknownNCT06322095
What this trial is testing

GH21 Combined With Previous Target Therapy or Immunotherapy in Patients With Advanced Solid Tumors

Who this might be right for
Patients With Advanced Solid TumorAdvanced Solid Tumor With Oncogenic Driver Mutations
Suzhou Genhouse Bio Co., Ltd. 72
Testing effectiveness (Phase 2)Ended earlyNCT02326844
What this trial is testing

BMN 673 (Talazoparib), an Oral PARP Inhibitor, in People With Deleterious BRCA1/2 Mutation-Associated Ovarian Cancer Who Have Had Prior PARP Inhibitor Treatment

Who this might be right for
Ovarian Cancer
National Cancer Institute (NCI) 3
Early research (Phase 1)UnknownNCT06356701
What this trial is testing

Tumor Nutritional Therapy in the First-line Treatment of Stage IV NSCLC

Who this might be right for
Long-Term Effects Secondary to Cancer Therapy
The First Affiliated Hospital of Dalian Medical University 120
Testing effectiveness (Phase 2)Study completedNCT04144608
What this trial is testing

Toripalimab Combined With Double Platinum-based Chemotherapy for Initially Unresectable NSCLC

Who this might be right for
Advanced Non Small Cell Lung Cancer
Yongchang Zhang 40
Large-scale testing (Phase 3)UnknownNCT04500704
What this trial is testing

Almonertinib Plus Chemotherapy as First-line Treatment in Patients With EGFR Concomitant Non-EGFR Driver Gene Mutant, Locally Advanced or Metastatic NSCLC

Who this might be right for
Non Small Cell Lung Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 166
Not applicableStudy completedNCT02608346
What this trial is testing

Circulating Tumor DNA and Follow-up of BRCA1 Mutation Carriers (CirCa 01)

Who this might be right for
Women With BRCA1 Germline Deleterious Mutation
Institut Curie 200
Not applicableUnknownNCT06081270
What this trial is testing

Prospective Study on Resistance-associated Mutations in Metastatic Lung Cancer

Who this might be right for
Lung Cancer
University of Milano Bicocca 20
Not applicableUnknownNCT03235765
What this trial is testing

Cancer Panel From Blood of Lung Cancer Patients

Who this might be right for
Non Small Cell Lung Cancer MetastaticNon Small Cell Lung Cancer Recurrent
Seoul National University Hospital 200
Not applicableUnknownNCT05764694
What this trial is testing

Correlation Between the Occurrence of School Bullying, Victimization, and the Occurrence of Deleterious Oral Habits.

Who this might be right for
BruxismNail BitingBullying of Child+1 more
Cairo University 356
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