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Results for “Driver Mutation”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04584255
What this trial is testing

Niraparib + Dostarlimab In BRCA Mutated Breast Cancer

Who this might be right for
Stage I Breast CancerStage II Breast CancerStage III Breast Cancer+5 more
Dana-Farber Cancer Institute 62
Not applicableStudy completedNCT02323347
What this trial is testing

Cut-Off Progesterone Values Deleterious for In Vitro Fertilization and Fresh Embryo Transfer

Who this might be right for
ProgesteroneFertilization in VitroInfertility+1 more
Fundacion Dexeus 1,901
Not applicableLooking for participantsNCT05835739
What this trial is testing

InheriteD brEast caNcer iTalian regIsTrY A Retrospective-prospective Observational Cohort Study to Evaluate Cancer Prevention Strategies in Women With a Deleterious Mutation in BRCA1-2

Who this might be right for
Breast Cancer
Centro di Riferimento Oncologico - Aviano 78
Not applicableUnknownNCT03710629
What this trial is testing

Explore Treatment Regimens and Clinical Outcomes of the NSCLC Patients With Different Dirver Genes

Who this might be right for
Non-small Cell Lung Cancer
The First Affiliated Hospital of Guangzhou Medical University 750
Large-scale testing (Phase 3)UnknownNCT05157776
What this trial is testing

A Phase III Trial of Neoadjuvant Sintilimab and Chemotherapy for NSCLC Harboring No Driver Mutations

Who this might be right for
NSCLC, Stage IIIAEGF-R Negative Non-Small Cell Lung CancerALK Negative NSCLC
Tongji University 72
Testing effectiveness (Phase 2)Study completedNCT03845296
What this trial is testing

Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

Who this might be right for
Deleterious BRCA1 Gene MutationDeleterious BRCA2 Gene MutationLoss of Heterozygosity+8 more
SWOG Cancer Research Network 64
Testing effectiveness (Phase 2)WithdrawnNCT03432676
What this trial is testing

Epacadostat and Pembrolizumab in Treating Participants With Advanced Pancreatic Cancer

Who this might be right for
ATM Gene MutationDeleterious BRCA1 Gene MutationDeleterious BRCA2 Gene Mutation+7 more
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)UnknownNCT02940990
What this trial is testing

SBRT in Multi-metastatic NSCLC Patients Which Are Pan-negative for Driver Mutations

Who this might be right for
NSCLCSBRTGM-CSF
Shanghai Chest Hospital 50
Testing effectiveness (Phase 2)Looking for participantsNCT06305715
What this trial is testing

Radiation Prior to TKI to Delay Progression in Advanced Driver-Mutated Non-small Cell Lung Cancers (RadiaNCe Lung X)

Who this might be right for
Non Small Cell Lung Cancer
Medical College of Wisconsin 34
Large-scale testing (Phase 3)Looking for participantsNCT05236946
What this trial is testing

Observation or Upfront Cranial RT in Oncogene Mutated NSCLC With Asymptomatic BM: A Phase III RCT

Who this might be right for
Asymptomatic Brain MetastasesDriver Mutation Positive Non-small Cell Lung Cancer
Tata Memorial Hospital 190
Not applicableLooking for participantsNCT04960839
What this trial is testing

Prophylactic Irradiation to the Contralateral Breast for BCAs Patients

Who this might be right for
Breast Cancer
Second Affiliated Hospital, Zhejiang University, School of Medicine 323
Testing effectiveness (Phase 2)Active Not RecruitingNCT05033756
What this trial is testing

Comprehensive Analysis of Predictors of the Treatment With Pembrolizumab and Olaparib in Patients With Unresectable or Metastatic HER2 Negative Breast Cancer and a Deleterious Germline Mutation or a Homologous Recombination Deficiency (COMPRENDO

Who this might be right for
Malignant Neoplasm of BreastBreast Cancer
Institut fuer Frauengesundheit 11
Early research (Phase 1)Study completedNCT03101839
What this trial is testing

Phase I Dose-Escalation Study of AZD4785 in Patients With Advanced Solid Tumours

Who this might be right for
Non-Small Cell Lung CancerAdvanced Solid Tumours
AstraZeneca 28
Testing effectiveness (Phase 2)Study completedNCT03779191
What this trial is testing

Alectinib in Combination With Bevacizumab in ALK Positive NSCLC

Who this might be right for
ALK Gene Rearrangement PositiveNon-Squamous Non-Small Cell Neoplasm of Lung
Instituto Nacional de Cancerologia de Mexico 41
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07652073
What this trial is testing

DAT-2645 in Patients With BRCA1/2 Mutations or HRD-Positive Ovarian Cancer

Who this might be right for
Advanced or Metastatic Ovarian Cancer
Danatlas Pharmaceuticals Co., Ltd 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07829744
What this trial is testing

Perioperative Targeted Therapy in Resectable or Potentially Resectable Stage III Non-small Cell Lung Cancer With Rare Driver Mutations

Who this might be right for
Lung Cancer (NSCLC)
Shanghai Zhongshan Hospital 190
Not applicableUnknownNCT04300361
What this trial is testing

Identifying Novel Variants in the DPYD Gene in Patients of Non-Western Descent

Who this might be right for
Neoplasms
Leiden University Medical Center 600
Early research (Phase 1)Looking for participantsNCT07069335
What this trial is testing

A Bioequivalence Study to Evaluate Pharmacokinetics and Safety of BR2022 and BR2022-1 in Patients With Deleterious or Suspected Deleterious Germline BRCA-Mutated Advanced Ovarian Cancer

Who this might be right for
Ovarian Cancer
Boryung Pharmaceutical Co., Ltd 24
Not applicableStudy completedNCT04740658
What this trial is testing

Prevent and Control COVID-19 Infection in Nursing Homes on the Risk of Death of Residents

Who this might be right for
Covid19
University Hospital, Toulouse 12,166
Early research (Phase 1)Active Not RecruitingNCT05598853
What this trial is testing

Intrathecal Double Checkpoint Inhibition

Who this might be right for
Leptomeningeal MetastasisNon-small Cell Lung Cancer Stage IVMelanoma Stage IV
University of Zurich 26
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