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Results for “Drug Metabolism and Pharmacokinetics”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Looking for participantsNCT07815678
What this trial is testing

First-in-human Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of ACCG-2671

Who this might be right for
Obesity
Aconcagua Bio, Inc. a wholly owned subsidiary of Structure Therapeutics 164
Not applicableStudy completedNCT01431326
What this trial is testing

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

Who this might be right for
AdenovirusAnesthesiaAnxiety+56 more
Daniel Benjamin 3,520
Early research (Phase 1)Study completedNCT02903914
What this trial is testing

Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumors

Who this might be right for
Metastatic CancerSolid TumorsColorectal Cancer (CRC)+7 more
Incyte Corporation 260
Early research (Phase 1)Study completedNCT00621699
What this trial is testing

Pharmacokinetic Drug Interaction Between Ezetimibe and Tacrolimus After Single Dose Administration in Healthy Subjects

Who this might be right for
PharmacokineticsDrug InteractionsHypercholesterolemia+1 more
University Medicine Greifswald 24
Early research (Phase 1)Study completedNCT00949091
What this trial is testing

Pharmacokinetics and Pharmacodynamics of TAK-875 in Subjects With Type 2 Diabetes

Who this might be right for
Diabetes Mellitus, Type 2
Takeda 60
Early research (Phase 1)Study completedNCT06395610
What this trial is testing

Effect of Erythromycin on the Absorption, Metabolism and Elimination of CHF6001 in Healthy Volunteers

Who this might be right for
Chronic Obstructive Pulmonary Disease
Chiesi Farmaceutici S.p.A. 24
Early research (Phase 1)Study completedNCT01264250
What this trial is testing

Assess the Safety, Tolerability and Pharmacokinetics After Single Ascending Intravenous Doses of AZD2927 in Healthy Male Volunteers

Who this might be right for
Healthy
AstraZeneca 48
Early research (Phase 1)Study completedNCT05015894
What this trial is testing

A Research Study Looking Into Blood Levels of the Medicine NNC0480-0389 in Participants With Reduced Kidney Function Compared to Participants With Normal Kidney Function

Who this might be right for
Diabetes Mellitus, Type 2
Novo Nordisk A/S 42
Testing effectiveness (Phase 2)Study completedNCT03818256
What this trial is testing

Assess the Safety, Efficacy, and Pharmacokinetics of Miricorilant (CORT118335) in Obese Adults With Schizophrenia or Bipolar Disorder Treated With Antipsychotic Medications

Who this might be right for
Antipsychotic-induced Weight Gain (AIWG)
Corcept Therapeutics 71
Early research (Phase 1)Study completedNCT06370819
What this trial is testing

A Research Study Looking Into Blood Levels of the Medicine NNC0519-0130 in the Body in Participants With Normal or Reduced Kidney Function

Who this might be right for
Diabetes Mellitus, Type 2
Novo Nordisk A/S 36
Early research (Phase 1)Looking for participantsNCT07731139
What this trial is testing

Learn How Different Amounts of the Study Medicine Called PF-08642534 Are Tolerated and Act in the Body of People Who Have Obesity

Who this might be right for
Obesity
Pfizer 120
Early research (Phase 1)Looking for participantsNCT07550816
What this trial is testing

Drug-drug Interaction Study of ZT002 Injection in Overweight and Obese Participants

Who this might be right for
Overweight,Obesity
Beijing QL Biopharmaceutical Co.,Ltd 60
Early research (Phase 1)Not Yet RecruitingNCT07777133
What this trial is testing

Evaluate the Metabolism, the Routes and Extent of Elimination, and Drug Levels of [14C]Navlimetostat (BMS-986504) in Healthy Female Participants

Who this might be right for
Healthy Female Participants
Bristol-Myers Squibb 6
Early research (Phase 1)Study completedNCT00472836
What this trial is testing

Study Examining The Effect Of Renal Impairment On Safety, Toleration And How The Body Processes An Experimental Drug

Who this might be right for
Obesity
Pfizer 17
Early research (Phase 1)Study completedNCT06478563
What this trial is testing

A Research Study Looking at Different Oral Formulations and the Effect of Food Intake on How the Medicine NNC0487-0111 Behaves in the Body of Participants Living With Overweight or Obesity

Who this might be right for
ObesityOverweight
Novo Nordisk A/S 133
Post-approval studies (Phase 4)Study completedNCT01309698
What this trial is testing

Drug Interaction of Vildagliptin (LAF237) With Voglibose in Japanese Patients With Type 2 Diabetes

Who this might be right for
Type 2 Diabetes
Novartis Pharmaceuticals 24
Early research (Phase 1)Study completedNCT02138799
What this trial is testing

Evaluate How a Drug That Alters Liver Enzymes (Rifampin) Affects the Metabolism of Enzalutamide in Men

Who this might be right for
Drug-Drug Interaction (DDI)Healthy SubjectsPharmacokinetics of Enzalutamide
Astellas Pharma Europe B.V. 28
Early research (Phase 1)Not Yet RecruitingNCT07797855
What this trial is testing

See How Safe a New Medicine (NNC0705-0002) is in Healthy People

Who this might be right for
Healthy VolunteersCardiometabolic Diseases
Novo Nordisk A/S 112
Testing effectiveness (Phase 2)Ended earlyNCT06987968
What this trial is testing

See if an Investigational Medicine Called VS-01 Can Help and How Safe it is in the Treatment of Patients With Overt Hepatic Encephalopathy

Who this might be right for
Hepatic EncephalopathyAcute on Chronic Liver Failure (ACLF)Decompensated Cirrhosis
Genfit 3
Early research (Phase 1)Study completedNCT02314442
What this trial is testing

An Investigational Drug, ALN-PCSSC, in Subjects With Elevated Low Density Lipoprotein Cholesterol (LDL-C)

Who this might be right for
Hypercholesterolemia
Alnylam Pharmaceuticals 70
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