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Results for “Durvalumab”

715 trials

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Showing 20 of 715 results

Large-scale testing (Phase 3)Active Not RecruitingNCT03164616
What this trial is testing

Study of Durvalumab + Tremelimumab With Chemotherapy or Durvalumab With Chemotherapy or Chemotherapy Alone for Patients With Lung Cancer (POSEIDON).

Who this might be right for
Non Small Cell Lung Cancer NSCLC
AstraZeneca 1,186
Testing effectiveness (Phase 2)UnknownNCT03994393
What this trial is testing

Non Small Cell Lung Cancer Trial of Durvalumab and Tremelimumab in Advanced Epidermal Growth Factor Receptor (EGFR) Mutant Disease.

Who this might be right for
EGFR Mutant Advanced Non Small Cell Lung Cancer
University of Sydney 100
Testing effectiveness (Phase 2)Ended earlyNCT04765709
What this trial is testing

Durvalumab and Chemotherapy Induction Followed by Durvalumab and Radiotherapy in Large Volume Stage III NSCLC

Who this might be right for
Non-small Cell Lung Cancer Stage III
Mario Negri Institute for Pharmacological Research 10
Testing effectiveness (Phase 2)Looking for participantsNCT06393816
What this trial is testing

FIRST-NEC (GFPC 01-2022) - Combination of Durvalumab With Etoposide and Platinum

Who this might be right for
Large Cell Neuroendocrine Carcinoma of the Lung
Centre Leon Berard 80
Large-scale testing (Phase 3)Looking for participantsNCT06467357
What this trial is testing

Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer

Who this might be right for
Biliary Tract Cancer
AstraZeneca 620
Early research (Phase 1)Active Not RecruitingNCT06218511
What this trial is testing

A Phase I Trial of IMA970A Plus Montanide in Combination With Durvalumab (Anti-PD-L1)

Who this might be right for
Hepatocellular Carcinoma
National Cancer Institute, Naples 10
Testing effectiveness (Phase 2)Active Not RecruitingNCT05856695
What this trial is testing

Durvalumab Plus Etoposide-free Chemotherapy in First-line Treatment of Extensive-disease Small-sell Lung Cancer (SCLC)

Who this might be right for
Small Cell Lung Cancer Extensive Stage
Intergroupe Francophone de Cancerologie Thoracique 67
Testing effectiveness (Phase 2)Ended earlyNCT04951115
What this trial is testing

A Trial With Chemotherapy, Immunotherapy, and Radiotherapy for Patients With Newly Diagnosed Stage IV Small Cell Lung Cancer

Who this might be right for
Small-cell Lung Cancer
Weill Medical College of Cornell University 6
Testing effectiveness (Phase 2)Active Not RecruitingNCT03691714
What this trial is testing

Durvalumab (MEDI4736) With Cetuximab in Previously Treated Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Who this might be right for
Recurrent Head and Neck CancerHead and Neck CancerHead and Neck Neoplasms+1 more
Trisha Wise-Draper 36
Not applicableStudy completedNCT03643484
What this trial is testing

IMFINZI Specific-Clinical Experience Investigation in Patients With NSCLC After Definitive Chemoradiation Therapy

Who this might be right for
Carcinoma, Non-Small-Cell Lung
AstraZeneca 634
Large-scale testing (Phase 3)Looking for participantsNCT05557838
What this trial is testing

Study of Durvalumab Plus Tremelimumab as First-line Treatment in Chinese Patients With Unresectable Hepatocellular Carinoma

Who this might be right for
Hepatocellular Carcinoma
AstraZeneca 210
Very early researchWithdrawnNCT04088032
What this trial is testing

Neoadjuvant Study of Abemaciclib, Durvalumab, and an Aromatase Inhibitor Early Stage Breast Cancer

Who this might be right for
Breast Cancer FemaleLocally Advanced Breast CancerHormone Receptor Positive Malignant Neoplasm of Breast
Alison Stopeck
Testing effectiveness (Phase 2)WithdrawnNCT05120622
What this trial is testing

Trial of Local Cystoscopic Injection of Tremelimumab Plus Systemic Durvalumab for High Risk Non-Muscle Invasive Bladder Cancer

Who this might be right for
Bladder CancerHigh-Risk CancerTremelimumab+2 more
University of British Columbia
Testing effectiveness (Phase 2)Looking for participantsNCT03907475
What this trial is testing

Durvalumab in Combination With Chemotherapy in Treating Patients With Advanced Solid Tumors, DURVA+ Trial

Who this might be right for
Locally Advanced Malignant Solid NeoplasmMetastatic Malignant Solid Neoplasm
National Cancer Institute (NCI) 115
Testing effectiveness (Phase 2)Study completedNCT03317457
What this trial is testing

Durvalumab and Tremelimumab Compared to Doxorubicin in Patients With Advanced or Metastatic Soft Tissue Sarcoma

Who this might be right for
Metastatic Adult Soft Tissue SarcomaRecurrent Adult Soft Tissue Sarcoma
AIO-Studien-gGmbH 103
Testing effectiveness (Phase 2)Active Not RecruitingNCT05000710
What this trial is testing

Concomitant Radiotherapy, Tremelimumab & Durvalumab for Advanced NSCLC Patients Progressing on First-line Immunotherapy

Who this might be right for
Metastatic or Locally Advanced NSCLC
Sheba Medical Center 29
Testing effectiveness (Phase 2)Study completedNCT02879617
What this trial is testing

A Clinical Trial of Durvalumab (MEDI4736) as 1st Line Therapy in Advanced Non-small Cell Lung Cancer Patients

Who this might be right for
Non-Small Cell Lung Cancer NSCLC
Academic Thoracic Oncology Medical Investigators Consortium 47
Large-scale testing (Phase 3)Looking for participantsNCT06103864
What this trial is testing

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer

Who this might be right for
Breast Cancer
AstraZeneca 625
Testing effectiveness (Phase 2)Study completedNCT04115111
What this trial is testing

Diadem to Investigate the Activity and Safety of Durvalumab

Who this might be right for
Pleura Mesothelioma
Mario Negri Institute for Pharmacological Research 57
Testing effectiveness (Phase 2)Study completedNCT02499328
What this trial is testing

Study to Assess MEDI4736 With Either AZD9150 or AZD5069 in Advanced Solid Tumors & Relapsed Metastatic Squamous Cell Carcinoma of Head & Neck

Who this might be right for
Advanced Solid Tumors & Metastatic Squamous Cell Carcinoma of the Head and Neck
AstraZeneca 340
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