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Results for “EGFR Wildtype”

111 trials

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Showing 20 of 111 results

Large-scale testing (Phase 3)Ended earlyNCT05223673
What this trial is testing

Phase 3 Study of Futuximab/Modotuximab in Combination With Trifluridine/Tipiracil Versus Trifluridine/Tipiracil Single Agent in Participants With Previously Treated Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Institut de Recherches Internationales Servier 7
Early research (Phase 1)Looking for participantsNCT07544992
What this trial is testing

Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas

Who this might be right for
Recurrent Astrocytoma, IDH-Mutant, Grade 4Recurrent Glioblastoma, IDH-Wildtype
City of Hope Medical Center 24
Testing effectiveness (Phase 2)UnknownNCT01755923
What this trial is testing

Gefitinib or Docetaxel as Second Line Therapy for Wild-type Epidermal Growth Factor Receptor (EGFR) NSCLC

Who this might be right for
Non-small Cell Lung Cancer
Peking Union Medical College Hospital 60
Post-approval studies (Phase 4)UnknownNCT02804646
What this trial is testing

Endostar Durative Transfusion Combined With Chemotherapy in the Treatment of Advanced Lung Adenocarcinoma

Who this might be right for
Adenocarcinoma of Lung
Anhui Provincial Hospital 100
Large-scale testing (Phase 3)Looking for participantsNCT06226857
What this trial is testing

Other Oncogene Mutations for Anti-EGFR Efficacy in Patients With Left-sided RAS-wild Type Metastatic Colorectal Cancer

Who this might be right for
Colorectal NeoplasmsChemotherapy EffectMolecular Sequence Variation
City Clinical Oncology Hospital No 1 355
Testing effectiveness (Phase 2)Ended earlyNCT04515394
What this trial is testing

Study of Tepotinib Combined With Cetuximab in Participants With Left-Sided RAS/BRAF Wild Type Metastatic Colorectal Cancer (PERSPECTIVE)

Who this might be right for
Colorectal Neoplasms
EMD Serono Research & Development Institute, Inc. 3
Early research (Phase 1)UnknownNCT02691871
What this trial is testing

Apatinib Plus Docetaxel as 2nd Line Treatment in Patients With Advanced Lung Adenocarcinoma Harboring Wild-type EGFR

Who this might be right for
Lung Adenocarcinoma
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 20
Testing effectiveness (Phase 2)Study completedNCT01003899
What this trial is testing

A Phase II Trial of Afatinib(BIBW 2992) in Third-line Treatment for Patients With Stage IIIB/IV Adenocarcinoma of the Lung Harbouring Wild-type Epidermal Growth Factor Receptor[EGFR]

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Boehringer Ingelheim 43
Large-scale testing (Phase 3)Not Yet RecruitingNCT07361484
What this trial is testing

Docetaxel Plus Plinabulin vs Docetaxel Plus Placebo in Advanced/Metastatic Non-Squamous NSCLC After PD-1/PD-L1 Therapy and Platinum Chemotherapy (DUBLIN-4)

Who this might be right for
Non-Small Cell Lung CancerNon-squamous Non-Small Cell Lung Cance
BeyondSpring Pharmaceuticals Inc. 442
Not applicableStudy completedNCT03564197
What this trial is testing

18F-PD-L1 PET/CT in Nivolumab Treated Patients With NSCLC

Who this might be right for
NSCLC Stage IV
The Netherlands Cancer Institute 80
Testing effectiveness (Phase 2)UnknownNCT02006043
What this trial is testing

Evaluate Erlotinib Efficacy and Safety as the 2nd/3rd Treatment in NSCLC With EGFR M(-) and C-met(-)

Who this might be right for
Non-small Cell Lung Cancer
Li Zhang 54
Not applicableNot Yet RecruitingNCT07191405
What this trial is testing

Clinical Study of Chemotherapy and Immunotherapy Combined With Lactobacillus Johnsonii in Patients With Multiple Irresectable Solid Tumors

Who this might be right for
ImmunotherapyChemotherapy
Second Affiliated Hospital, School of Medicine, Zhejiang University 156
Testing effectiveness (Phase 2)Study completedNCT00788957
What this trial is testing

Panitumumab Combination Study With Rilotumumab or Ganitumab in Wild-type Kirsten Rat Sarcoma Virus Oncogene Homolog (KRAS) Metastatic Colorectal Cancer (mCRC)

Who this might be right for
Colon CancerColorectal CancerGastrointestinal Cancer+2 more
NantBioScience, Inc. 177
Testing effectiveness (Phase 2)Ended earlyNCT02556593
What this trial is testing

IMRT Combined With Erlotinib for EGFR Wild Type Non-small Cell Lung Cancer With 4-10 Brain Metastases

Who this might be right for
Non-Small Cell Lung Carcinoma
Sun Yat-sen University 12
Testing effectiveness (Phase 2)UnknownNCT03405272
What this trial is testing

Safety and Efficacy of Recombinant Anti-EGFR Monoclonal Antibody in Patients With Wild-type RAS and BRAF mCRC

Who this might be right for
Metastatic Colorectal Cancer
Sinocelltech Ltd. 110
Testing effectiveness (Phase 2)UnknownNCT03703596
What this trial is testing

Anlotinib Versus Docetaxel as the Second-line Treatment in EGFR Wild Type Patients With Advanced NSCLC

Who this might be right for
Lung CancerLung Cancer Metastatic
Sichuan Cancer Hospital and Research Institute 88
Testing effectiveness (Phase 2)Looking for participantsNCT06554613
What this trial is testing

Olanzapine Impact on First-line Immunotherapy for Advanced EGFR-negative NSCLC

Who this might be right for
Non-Small Cell Lung Cancer
Second Affiliated Hospital of Nanchang University 156
Testing effectiveness (Phase 2)UnknownNCT02631460
What this trial is testing

S1 vs.Pemetrexed Plus Carboplatin in Patients With EGFR Wild Type Stage IIIB or IV Nonsquamous NSCLC

Who this might be right for
NSCLC
Sun Yat-sen University 470
Testing effectiveness (Phase 2)Ended earlyNCT00387894
What this trial is testing

Erlotinib in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma

Who this might be right for
Adult Brain Tumors
Michael Prados 6
Testing effectiveness (Phase 2)Ended earlyNCT02621333
What this trial is testing

Chemotherapy Combined Autologous Cytokine-induced Killer Cells in Naive Stage IV EGFR-wild Type Lung Adenocarcinoma

Who this might be right for
Lung Adenocarcinoma
Henan Cancer Hospital 280
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