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Results for “EGFR-Mutant Lung Cancer”

234 trials

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Showing 20 of 234 results

Testing effectiveness (Phase 2)Study completedNCT03623750
What this trial is testing

E GFR TKI and EGF-P TI C Ombination in EGFR mutA nt NSCL C

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Instituto Oncológico Dr Rosell 23
Not applicableWithdrawnNCT05116618
What this trial is testing

Detection of Resistance Mechanisms in Cerebrospinal Fluid for EGFR-mutant, ALK- and ROS1-rearranged

Who this might be right for
Non-Small Cell Lung Cancer
University of Colorado, Denver
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07343479
What this trial is testing

Sacituzumab Tirumotecan Plus Third-Generation TKI With/Without Radiotherapy for EGFR-Mutant NSCLC Brain Metastases

Who this might be right for
NSCLC (Advanced Non-small Cell Lung Cancer)EGFR Gene MutationsBrain Metastasis
Zhejiang Cancer Hospital 45
Large-scale testing (Phase 3)Active Not RecruitingNCT06396065
What this trial is testing

Phase III Study of AK112 for NSCLC Patients

Who this might be right for
Non-Squamous Non-small Cell Lung Cancer
Summit Therapeutics 420
Testing effectiveness (Phase 2)Looking for participantsNCT06363734
What this trial is testing

Osimertinib Plus Dalpiciclib in Patients With EGFR-mutant, CDK4/6 Pathway Aberrant, Advanced Non-small Cell Lung Cancer Following Acquired Resistance to Third-generation EGFR TKI: a Phase II Trial

Who this might be right for
Non-small Cell Lung CancerEGFR Activating MutationCell Cycle Deregulation+1 more
Tianjin Medical University Cancer Institute and Hospital 32
Testing effectiveness (Phase 2)UnknownNCT03349203
What this trial is testing

Icotinib as Neoadjuvant and Adjuvant Therapy in EGFR-mutant Stage IIIB or Oligometastasis Non-small Cell Lung Cancer

Who this might be right for
EGF-R Positive Non-Small Cell Lung Cancer
Betta Pharmaceuticals Co., Ltd. 60
Early research (Phase 1)Active Not RecruitingNCT02496663
What this trial is testing

Osimertinib and Necitumumab in Treating Patients With EGFR-Mutant Stage IV or Recurrent Non-small Cell Lung Cancer Who Have Progressed on a Previous EGFR Tyrosine Kinase Inhibitor

Who this might be right for
Metastatic Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell CarcinomaStage IV Lung Cancer AJCC v8
National Cancer Institute (NCI) 138
Not applicableLooking for participantsNCT07806604
What this trial is testing

Real World Study of Icotinib in Adjuvant Post Surgical Treatment for Stage IA2 High Risk to IB EGFR Mutant Non Small Cell Lung Cancer

Who this might be right for
NSCLC (Non-small Cell Lung Cancer)
Betta Pharmaceuticals Co., Ltd. 2,572
Testing effectiveness (Phase 2)Study completedNCT02535338
What this trial is testing

Erlotinib Hydrochloride and Onalespib Lactate in Treating Patients With Recurrent or Metastatic EGFR-Mutant Non-small Cell Lung Cancer

Who this might be right for
Recurrent Lung Non-Small Cell CarcinomaStage IV Lung Non-Small Cell Cancer AJCC v7
National Cancer Institute (NCI) 11
Not applicableLooking for participantsNCT07837739
What this trial is testing

Adjuvant EGFR-TKI Therapy After Surgery for EGFR-Mutant High-Risk Stage IA2-IIB NSCLC

Who this might be right for
Non-Small Cell Lung Cancer
Tongji Hospital 100
Early research (Phase 1)Study completedNCT05926180
What this trial is testing

Assessing the Effect of DZD9008 on the Pharmacokinetics of the Cocktail Probes Representative for CYP3A4, P-gp, BCRP and OATP1B1 in Patients with EGFR or HER2 Mutant Advanced Non-small Cell Lung Cancer (WU-KONG19)

Who this might be right for
Non-small Cell Lung Cancer
Dizal Pharmaceuticals 25
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07545213
What this trial is testing

Efficacy and Safety of SKB264 Plus Anlotinib in EGFR-TKI-Resistant Advanced NSCLC With Liver Metastasis

Who this might be right for
Non-small Cell Lung CancerEGFR Mutant Advanced Non-small Cell Lung Cancer
The Fourth Affiliated Hospital of Zhejiang University School of Medicine 27
Large-scale testing (Phase 3)Study completedNCT03802240
What this trial is testing

Sintilimab ± IBI305 Plus Chemotherapy (Pemetrexed + Cisplatin) for EGFRm + Locally Advanced or Metastasis Non-Squamous NSCLC Patients After EGFR-TKI Treatment Failure

Who this might be right for
Non-Squamous Non-Small Cell Lung Cancer
Innovent Biologics (Suzhou) Co. Ltd. 492
Large-scale testing (Phase 3)Active Not RecruitingNCT05870319
What this trial is testing

A Phase III Study of SKB264 for EGFR Mutant NSCLC Patients

Who this might be right for
Non-small Cell Lung Cancer
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. 376
Not applicableStudy completedNCT07267247
What this trial is testing

Cancer Therapy-Related Cardiac Dysfunction Associated With EGFR-TKIs in Advanced EGFR-mutant Non-small Cell Lung Cancer

Who this might be right for
Non-Small Cell Lung Cancer (MeSH Term: Carcinoma, Non-Small-Cell Lung)Drug-Related Side Effects and Adverse Reactions (MeSH Term)Egfr Tyrosine Kinase Inhibitor+1 more
Taichung Veterans General Hospital 100
Testing effectiveness (Phase 2)UnknownNCT05007938
What this trial is testing

Befotertinib and Icotinib in Treatment-naive Patients With Advanced EGFR-Mutant Lung Cancer

Who this might be right for
Non-Small Cell Lung Cancer
Betta Pharmaceuticals Co., Ltd. 30
Testing effectiveness (Phase 2)Ended earlyNCT04971187
What this trial is testing

Bintrafusp Alfa With Chemotherapy for Tyrosine Kinase Inhibitor-Resistant EGFR-Mutant Non-small Cell Lung Cancer

Who this might be right for
Locally Advanced Lung Non-Squamous Non-Small Cell CarcinomaMetastatic Lung Non-Squamous Non-Small Cell CarcinomaStage III Lung Cancer AJCC v8+7 more
M.D. Anderson Cancer Center 3
Testing effectiveness (Phase 2)Looking for participantsNCT07535437
What this trial is testing

Ivonescimab in Combination With Dato-DXd or Osimertinib in People With Non-Small Cell Lung Cancer

Who this might be right for
Non-Small Cell Lung Cancer
Memorial Sloan Kettering Cancer Center 66
Testing effectiveness (Phase 2)Temporarily pausedNCT02470065
What this trial is testing

Neoadjuvant Afatinib in Early Stage Non Small Cell Lung Cancer.

Who this might be right for
Non Small Cell Lung Cancer
European Organisation for Research and Treatment of Cancer - EORTC 38
Early research (Phase 1)Study completedNCT01320059
What this trial is testing

Study of 18F-Fluoro-PEG6-IPQA

Who this might be right for
Lung Cancer
M.D. Anderson Cancer Center 6
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