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Results for “ER-positive Her2-negative Early Breast Cancer”

51 trials

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Showing 20 of 51 results

Not applicableStudy completedNCT03961880
What this trial is testing

Impact of Recurrence Score on Adjuvant Treatment Decisions in Breast Cancer Patients

Who this might be right for
Breast Cancer Female
University Hospital Tuebingen 270
Not applicableUnknownNCT05734950
What this trial is testing

Biological Characteristics of Older Women (> 70 Years) With ER Positive, HER2 Negative Early Breast Cancer

Who this might be right for
Breast Cancer Female
Royal Marsden NHS Foundation Trust 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT05069038
What this trial is testing

Clinical Trial Assessing the Safety of Neoadjuvant Palbociclib in Combination With Endocrine Therapy

Who this might be right for
Breast Cancer
University of Nebraska 51
Testing effectiveness (Phase 2)Looking for participantsNCT05020860
What this trial is testing

Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer

Who this might be right for
Breast CancerBreast NeoplasmBreast Cancer Female+8 more
Baylor Breast Care Center 185
Large-scale testing (Phase 3)UnknownNCT01093235
What this trial is testing

Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Nonmetastatic Breast Cancer

Who this might be right for
Breast CancerCardiac ToxicityPerioperative/Postoperative Complications
Cambridge University Hospitals NHS Foundation Trust 800
Large-scale testing (Phase 3)Study completedNCT04629846
What this trial is testing

Study in Participants With Early-Stage or Locally Advanced Human Epidermal Growth Factor Receptor (HER) 2-Positive and Estrogen Receptor/Progesterone Receptor Negative Breast Cancer to Evaluate the Efficiency and Safety of Treatment With Trastuzumab Plus (+) QL1209/Pertuzumab + Docetaxel.

Who this might be right for
Breast Cancer
Qilu Pharmaceutical Co., Ltd. 517
Not applicableEnded earlyNCT03137693
What this trial is testing

Preoperative Stereotactic Ablative Body Radiotherapy (SABR) for Early-Stage Breast Cancer

Who this might be right for
Breast CancerBreast Cancer FemaleBreast Adenocarcinoma
H. Lee Moffitt Cancer Center and Research Institute 20
Testing effectiveness (Phase 2)Looking for participantsNCT06259929
What this trial is testing

NEOadjuvant Abemaciclib and GIredestrant TriaL in Patients with ER-positive, HER2-negative Early Breast Cancer

Who this might be right for
Breast Cancer
Fondazione Oncotech 51
Testing effectiveness (Phase 2)Study completedNCT05659563
What this trial is testing

Preoperative Window Opportunity Study With Giredestrant or Tamoxifen in Premenopausal Women With ER+/HER2[-] & Ki67≥10%

Who this might be right for
Breast CancerBreast Cancer, Early-Onset
MedSIR 92
Large-scale testing (Phase 3)Active Not RecruitingNCT03725059
What this trial is testing

Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756)

Who this might be right for
Breast Cancer
Merck Sharp & Dohme LLC 1,240
Not applicableStudy completedNCT01928186
What this trial is testing

FLT PET in Measuring Treatment Response in Patients With Newly Diagnosed Estrogen Receptor-Positive, HER2-Negative Stage I-III Breast Cancer

Who this might be right for
Estrogen Receptor PositiveHER2/Neu NegativeMale Breast Carcinoma+7 more
University of Washington 28
Large-scale testing (Phase 3)Temporarily pausedNCT06671912
What this trial is testing

Testing Low Dose Tamoxifen for Invasive Breast Cancer, LoTam Trial

Who this might be right for
Anatomic Stage 0 Breast Cancer AJCC v8Anatomic Stage 1 Breast Cancer AJCC v8Anatomic Stage IIA Breast Cancer AJCC v8+4 more
Alliance for Clinical Trials in Oncology 1,556
Testing effectiveness (Phase 2)Looking for participantsNCT04985266
What this trial is testing

A Trial of Early Detection of Molecular Relapse With Circulating Tumour DNA Tracking and Treatment With Palbociclib Plus Fulvestrant Versus Standard Endocrine Therapy in Patients With ER Positive HER2 Negative Breast Cancer

Who this might be right for
ER+ Breast CancerHER2-negative Breast Cancer
Royal Marsden NHS Foundation Trust 1,100
Early research (Phase 1)Active Not RecruitingNCT05870579
What this trial is testing

[177Lu]Lu-NeoB in Combination With Ribociclib and Fulvestrant in Participants With ER+, HER2- and GRPR+ Advanced Breast Cancer

Who this might be right for
Breast Cancer
Novartis Pharmaceuticals 28
Early research (Phase 1)Study completedNCT01576666
What this trial is testing

Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors

Who this might be right for
Dose EscalationSafetyPreliminary Efficacy+9 more
Novartis Pharmaceuticals 120
Testing effectiveness (Phase 2)Ended earlyNCT04675827
What this trial is testing

De-escalation Adjuvant Chemo in HER2+/ER-/node-neg Early BC Patients Who Achieved PCR After Neoadjuvant Chemo & Dual HER2 Blockade

Who this might be right for
HER2-positive Breast CancerER-Negative Breast CancerPR-Negative Breast Cancer+1 more
Jules Bordet Institute 139
Post-approval studies (Phase 4)Looking for participantsNCT05333328
What this trial is testing

OFS in Premenopausal Node+ Breast Cancer With Low Genomic Risk

Who this might be right for
Breast CancerEstrogen Receptor Positive TumorHER2-negative Breast Cancer+2 more
Gangnam Severance Hospital 418
Not applicableWithdrawnNCT03080428
What this trial is testing

Assessment of Genomic Test Impact on Shared Decision of Adjuvant Chemotherapy in ER-positive, Her2-negative Early Breast Cancer

Who this might be right for
ER-positive Her2-negative Early Breast Cancer
UNICANCER
Large-scale testing (Phase 3)Looking for participantsNCT06492616
What this trial is testing

Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Who this might be right for
Breast Cancer
Stemline Therapeutics, Inc. 4,220
Not applicableActive Not RecruitingNCT04118192
What this trial is testing

NOSTRA-Feasibility Study: A Study Looking at Ultrasound Guided Biopsies for Breast Cancer

Who this might be right for
Breast Cancer
University of Birmingham 72
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