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Results for “ESR1 Gene Mutation”

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Showing 20 of 0 results

Not applicableLooking for participantsNCT07563595
What this trial is testing

Elacestrant in Patients With ER+ HER2- ESR1-mutated Locally Advanced or Metastatic Breast Cancer

Who this might be right for
Breast Cancer
iOMEDICO AG 500
Large-scale testing (Phase 3)Looking for participantsNCT05696626
What this trial is testing

Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

Who this might be right for
Metastatic Breast Cancer
LeonaBio 600
Not applicableLooking for participantsNCT06417801
What this trial is testing

Minimally Interventional Study on Prevalence of Emerging ESR1 Mutations in Liquid Biopsy in Three Cohorts of Patients With Breast Cancer in Comparison With Patient's Baseline ESR1 Mutation Status as Defined by Tissue Profiling.

Who this might be right for
Metastatic Breast Cancer
AstraZeneca 170
Very early researchStudy completedNCT02913430
What this trial is testing

Treatment of Metastatic Breast Cancer With Fulvestrant Plus Palbociclib or Tamoxifen Plus Palbociclib

Who this might be right for
Metastatic Breast Cancer
Shannon Puhalla 7
Not applicableTemporarily pausedNCT02993068
What this trial is testing

Stand up to Cancer: MAGENTA (Making Genetic Testing Accessible)

Who this might be right for
BARD1 Gene MutationBRCA1 Gene MutationBRCA2 Gene Mutation+12 more
M.D. Anderson Cancer Center 5,200
Not applicableLooking for participantsNCT06548919
What this trial is testing

Current Status of Treatment for Chinese Patients With ESR1-mutated HR+/HER2-advanced Breast Cancer

Who this might be right for
ESR1 Gene MutationAdvanced Breast Cancer
SciClone Pharmaceuticals 450
Testing effectiveness (Phase 2)UnknownNCT03879174
What this trial is testing

Pembrolizumab And Tamoxifen Among Women With Advanced Hormone Receptor Positive Breast Cancer And Esr1 Mutation

Who this might be right for
Breast Cancer Female
Mediclinic Middle East 25
Early research (Phase 1)Ended earlyNCT02476955
What this trial is testing

Open-label Phase 1b Study of ARQ 092 in Combination With Anastrozole

Who this might be right for
Solid TumorsOvarian CancerEndometrial Cancer
ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA) 41
Not applicableStudy completedNCT00342498
What this trial is testing

Estrogen Receptor Gene Mutations

Who this might be right for
MutationsHormones
National Institute of Environmental Health Sciences (NIEHS)
Large-scale testing (Phase 3)Active Not RecruitingNCT06065748
What this trial is testing

Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)

Who this might be right for
Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer
Hoffmann-La Roche 1,050
Early research (Phase 1)UnknownNCT04631835
What this trial is testing

Phase I Study of the HS-10352 in Patients With Advanced Breast Cancer

Who this might be right for
Breast Cancer
Jiangsu Hansoh Pharmaceutical Co., Ltd. 54
Not applicableStudy completedNCT03318263
What this trial is testing

CIrCuLAting Dna ESr1 Gene Mutations Analysis

Who this might be right for
Breast Cancer
Institut de Cancérologie de Lorraine 146
Not applicableLooking for participantsNCT06127979
What this trial is testing

Changes in Ki67 Expression in People With Breast Cancer Receiving Endocrine Therapy Before Surgery

Who this might be right for
Breast Cancer
Memorial Sloan Kettering Cancer Center 42
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07499999
What this trial is testing

Randomized Double-Blind Phase II Trial of Baby Exemestane Versus Baby Tamoxifen in Post-Menopausal Women at High Risk for Breast Cancer

Who this might be right for
Breast CancerDuctal CarcinomaEstrogen-receptor-positive Breast Cancer+4 more
Dana-Farber Cancer Institute 140
Early research (Phase 1)WithdrawnNCT04602117
What this trial is testing

ISPY-P1.01:Evaluating the Safety of Weekly Paclitaxel With Trastuzumab Duocarmazine (SYD985) in Patients With Metastatic Cancer

Who this might be right for
HER2-positive Breast CancerHER2 LowSYD-985+24 more
QuantumLeap Healthcare Collaborative
Testing effectiveness (Phase 2)Study completedNCT03781063
What this trial is testing

Evaluation of Lasofoxifene Versus Fulvestrant in Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

Who this might be right for
Locally Advanced or Metastatic Breast Cancer
Sermonix Pharmaceuticals Inc. 100
Post-approval studies (Phase 4)Ended earlyNCT05183828
What this trial is testing

Effect of HSD3B1 (1245C) Gene Mutation on Treatment of Stage I-III Breast Cancer

Who this might be right for
Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8+2 more
University of Washington 62
Large-scale testing (Phase 3)Study completedNCT03079011
What this trial is testing

PAlbociclib and Circulating Tumor DNA for ESR1 Mutation Detection

Who this might be right for
Metastatic Breast Cancer
UNICANCER 1,017
Not applicableUnknownNCT06544577
What this trial is testing

Safety of Elacestrant in ER+/HER2- and ESR1 Mutations MBC

Who this might be right for
ESR1 Gene MutationAdvanced Breast CancerSafety
SciClone Pharmaceuticals 350
Testing effectiveness (Phase 2)Looking for participantsNCT06993844
What this trial is testing

Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsAdvanced Breast Cancer
Ensem Therapeutics 233
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