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Results for “Egfr Tyrosine Kinase Inhibitor”

316 trials

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Showing 20 of 316 results

Testing effectiveness (Phase 2)Looking for participantsNCT06567015
What this trial is testing

Study of FIH of STX-241 in Locally Advanced or Metastatic NSCLC Resistant to EGFR TKIs

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)
Pierre Fabre Medicament 171
Testing effectiveness (Phase 2)Study completedNCT03623750
What this trial is testing

E GFR TKI and EGF-P TI C Ombination in EGFR mutA nt NSCL C

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Instituto Oncológico Dr Rosell 23
Testing effectiveness (Phase 2)Study completedNCT00615758
What this trial is testing

Erlotinib as 1st Line Treatment in NSCLC Stage IIIB/IV

Who this might be right for
Non Small Cell Lung Cancer
Hellenic Oncology Research Group 50
Post-approval studies (Phase 4)UnknownNCT04864717
What this trial is testing

Doxycycline vs Isotretinoin for Acneiform Eruptions of TKI

Who this might be right for
Acneiform EruptionsCancer, Treatment-Related
Lady Davis Institute 98
Not applicableWithdrawnNCT05116618
What this trial is testing

Detection of Resistance Mechanisms in Cerebrospinal Fluid for EGFR-mutant, ALK- and ROS1-rearranged

Who this might be right for
Non-Small Cell Lung Cancer
University of Colorado, Denver
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07343479
What this trial is testing

Sacituzumab Tirumotecan Plus Third-Generation TKI With/Without Radiotherapy for EGFR-Mutant NSCLC Brain Metastases

Who this might be right for
NSCLC (Advanced Non-small Cell Lung Cancer)EGFR Gene MutationsBrain Metastasis
Zhejiang Cancer Hospital 45
Large-scale testing (Phase 3)UnknownNCT01405079
What this trial is testing

Gefitinib Versus Vinorelbine/Platinum as Adjuvant Treatment in Stage II-IIIA(N1-N2) NSCLC With EGFR Mutation

Who this might be right for
Non-small Cell Lung Cancer
Guangdong Association of Clinical Trials 222
Large-scale testing (Phase 3)Looking for participantsNCT07185997
What this trial is testing

Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

Who this might be right for
Non-Small-Cell Lung CancerMetastatic Non-Small-Cell Lung CancerAdvanced Non-Small-Cell Lung Cancer+3 more
ArriVent BioPharma, Inc.
Testing effectiveness (Phase 2)Ended earlyNCT02335944
What this trial is testing

Study of Safety and Efficacy of EGFR-TKI EGF816 in Combination With cMET Inhibitor INC280 in Adult Patients With EGFR Mutated Non Small Cell Lung Cancer.

Who this might be right for
Non Small Cell Lung Cancer
Novartis Pharmaceuticals 177
Early research (Phase 1)Active Not RecruitingNCT02496663
What this trial is testing

Osimertinib and Necitumumab in Treating Patients With EGFR-Mutant Stage IV or Recurrent Non-small Cell Lung Cancer Who Have Progressed on a Previous EGFR Tyrosine Kinase Inhibitor

Who this might be right for
Metastatic Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell CarcinomaStage IV Lung Cancer AJCC v8
National Cancer Institute (NCI) 138
Testing effectiveness (Phase 2)Study completedNCT00492206
What this trial is testing

Study of Cetuximab With Radiation Followed by Consolidation Chemotherapy for NSCLC

Who this might be right for
Non Small Cell Lung Cancer (NSCLC)
University of Pittsburgh 40
Early research (Phase 1)Study completedNCT00480584
What this trial is testing

A Phase I Trial of Capecitabine in Combination With Gemcitabine and Erlotinib for Advanced Pancreatic Cancer

Who this might be right for
Metastatic Pancreatic Carcinoma
H. Lee Moffitt Cancer Center and Research Institute 20
Testing effectiveness (Phase 2)Ended earlyNCT00343187
What this trial is testing

A Phase II Study of ACZONE™ (Dapsone) Gel, 5% As a Treatment For Tarceva® (Erlotinib)Related Rash

Who this might be right for
RashNon-small-Cell Lung Cancer
Allergan 2
Large-scale testing (Phase 3)Study completedNCT03515837
What this trial is testing

Study of Pemetrexed + Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With Tyrosine Kinase Inhibitor- (TKI)-Resistant Epidermal Growth Factor Receptor- (EGFR)-Mutated Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-789/KEYNOTE-789)

Who this might be right for
Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC 492
Testing effectiveness (Phase 2)Active Not RecruitingNCT04868877
What this trial is testing

Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR, Anti-c-MET Bispecific Antibody, in Advanced NSCLC and Other Solid Tumors, Alone and in Combination

Who this might be right for
Non-Small Cell Lung Cancer MetastaticGastric CancerEsophageal Squamous Cell Carcinoma+2 more
Merus B.V. 194
Testing effectiveness (Phase 2)Study completedNCT05378360
What this trial is testing

DWP708 for Treating Epidermal Growth Factor Receptor Inhibitor Related Skin Toxicities

Who this might be right for
Rash Acneiform
Daewoong Pharmaceutical Co. LTD. 96
Early research (Phase 1)Study completedNCT00083057
What this trial is testing

Gefitinib, Paclitaxel, and Radiation Therapy in Treating Patients With Advanced or Recurrent Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Head and Neck Cancer
National Institutes of Health Clinical Center (CC) 30
Testing effectiveness (Phase 2)Study completedNCT00552149
What this trial is testing

Biliary Cancers: EGFR INhibitor, Gemcitabine and Oxaliplatin

Who this might be right for
Advanced Biliary Cancer
Gustave Roussy, Cancer Campus, Grand Paris 150
Large-scale testing (Phase 3)Study completedNCT02284139
What this trial is testing

Pilot Trial of EGF Ointment for the Patients With EGFR-i Related Skin Side Effects

Who this might be right for
Non-small Cell Lung CancerPancreatic CancerColorectal Cancer
Dong-A University Hospital 90
Large-scale testing (Phase 3)Study completedNCT03802240
What this trial is testing

Sintilimab ± IBI305 Plus Chemotherapy (Pemetrexed + Cisplatin) for EGFRm + Locally Advanced or Metastasis Non-Squamous NSCLC Patients After EGFR-TKI Treatment Failure

Who this might be right for
Non-Squamous Non-Small Cell Lung Cancer
Innovent Biologics (Suzhou) Co. Ltd. 492
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