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Results for “Elevated LDL-C”

132 trials

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Showing 20 of 132 results

Testing effectiveness (Phase 2)Study completedNCT03060577
What this trial is testing

An Extension Trial of Inclisiran in Participants With Cardiovascular Disease and High Cholesterol

Who this might be right for
Atherosclerotic Cardiovascular DiseaseSymptomatic AtherosclerosisType2 Diabetes+1 more
Novartis Pharmaceuticals 382
Testing effectiveness (Phase 2)Study completedNCT05421078
What this trial is testing

A Dose-Finding Study in Japanese Patients to Evaluate the Effect of Obicetrapib as an Adjunct to Stable Statin Therapy.

Who this might be right for
DyslipidemiaHypercholesterolemiaHigh Cholesterol
NewAmsterdam Pharma 102
Post-approval studies (Phase 4)Looking for participantsNCT06501443
What this trial is testing

LATAM LOWERS LDL-C

Who this might be right for
Hypercholesterolaemia
Novartis Pharmaceuticals 520
Early research (Phase 1)Not Yet RecruitingNCT07074236
What this trial is testing

Pharmacokinetics and Pharmacodynamics Study

Who this might be right for
Primary Hypercholesterolemia or Combined Hyperlipidemia Characterized by Elevated LDL-C
Qilu Pharmaceutical Co., Ltd. 48
Large-scale testing (Phase 3)Study completedNCT03001076
What this trial is testing

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) as Add-on to Ezetimibe Therapy in Patients With Elevated LDL-C (CLEAR Tranquility)

Who this might be right for
HypercholesterolemiaAtherosclerosisStatin Adverse Reaction
Esperion Therapeutics, Inc. 269
Early research (Phase 1)Study completedNCT05905068
What this trial is testing

Adult Subjects With Elevated Low-Density Lipoprotein-Cholesterol to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects

Who this might be right for
To Reduce the LDL-C Level in Hypercholesteremia Adult PatientsCombination for Subgroup High LDL-c Patients With Other Comorbidities
Ikaria Bioscience Pty Ltd 32
Early research (Phase 1)Study completedNCT01618916
What this trial is testing

LY3015014 in Otherwise Healthy Participants With High Low-density Lipoprotein (LDL) Cholesterol

Who this might be right for
Healthy Volunteers
Eli Lilly and Company 51
Large-scale testing (Phase 3)Ended earlyNCT01414166
What this trial is testing

Niacin/Laropiprant Tablet for South and Southeast Asians With Low High-Density Lipoprotein Cholesterol (LDL-C) at Risk for Cardiovascular Disease (MK-0524A-108)

Who this might be right for
Dyslipidemia
Merck Sharp & Dohme LLC 244
Early research (Phase 1)Enrolling By InvitationNCT06504043
What this trial is testing

A Study on Evaluating the Safety of HST101 in Healthy Chinese Participants

Who this might be right for
HypercholesterolemiaHealthy VolunteersLDL-Cholesterol
Hasten Biopharmaceutical Co., Ltd. 30
Large-scale testing (Phase 3)Not Yet RecruitingNCT07441317
What this trial is testing

QLC7401 in the Treatment of Primary Hypercholesterolemia or Mixed Hyperlipidemia With Elevated Low Density Lipoprotein Cholesterol (LDL-C)

Who this might be right for
Primary Hypercholesterolemia or Mixed Hyperlipidemia
Qilu Pharmaceutical Co., Ltd. 780
Early research (Phase 1)Study completedNCT00027287
What this trial is testing

Laser and Medical Treatment of Diabetic Macular Edema

Who this might be right for
Diabetes MellitusMacular Edema
National Eye Institute (NEI) 60
Large-scale testing (Phase 3)Study completedNCT00082251
What this trial is testing

Safety & Efficacy of a Combination Niacin ER/Simvastatin in Patients With Dyslipidemia: A Dose-Ranging Study - SEACOAST

Who this might be right for
Hypercholesterolemia
Kos Pharmaceuticals
Testing effectiveness (Phase 2)Study completedNCT01375764
What this trial is testing

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects

Who this might be right for
Hyperlipidemia
Amgen 160
Early research (Phase 1)Looking for participantsNCT06980428
What this trial is testing

Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4954 in Healthy Adult Participants With or Without Elevated Lipoprotein (a) (Lp[a]) Levels, and Participants With Dyslipidemia

Who this might be right for
Healthy ParticipantsDyslipidemia
AstraZeneca 136
Early research (Phase 1)Not Yet RecruitingNCT07001787
What this trial is testing

Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of HS-10510 in Healthy Subjects

Who this might be right for
Dyslipidemia
Jiangsu Hansoh Pharmaceutical Co., Ltd. 88
Large-scale testing (Phase 3)UnknownNCT04806893
What this trial is testing

Study of Long-Term Efficacy and Safety of LIB003 in CVD or High Risk for CVD Patients Needing Further LDL-C Reduction

Who this might be right for
Cardiovascular Risk FactorCardiovascular DiseasesCardiovascular Stroke+1 more
LIB Therapeutics LLC 900
Testing effectiveness (Phase 2)Study completedNCT04753606
What this trial is testing

Randomized Study of Obicetrapib as an Adjunct to Statin Therapy

Who this might be right for
DyslipidemiasHigh CholesterolHypercholesterolemia
NewAmsterdam Pharma 120
Large-scale testing (Phase 3)Study completedNCT01624142
What this trial is testing

Trial Assessing Long Term USe of PCSK9 Inhibition in Subjects With Genetic LDL Disorders

Who this might be right for
Severe Familial Hypercholesterolemia
Amgen 300
Large-scale testing (Phase 3)Study completedNCT01763918
What this trial is testing

Reduction of LDL-C With PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder Study-2

Who this might be right for
Hyperlipidemia
Amgen 331
Large-scale testing (Phase 3)Study completedNCT04659863
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Novartis Pharmaceuticals 13
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