Early research (Phase 1)Study completedNCT01959971What this trial is testingEffect of Alirocumab on Lipid Metabolism in Adults With Elevated LDL-CholesterolWho this might be right forHypercholesterolemia Sanofi 20
Early research (Phase 1)Not Yet RecruitingNCT07074236What this trial is testingPharmacokinetics and Pharmacodynamics StudyWho this might be right forPrimary Hypercholesterolemia or Combined Hyperlipidemia Characterized by Elevated LDL-C Qilu Pharmaceutical Co., Ltd. 48
Not applicableLooking for participantsNCT06439654What this trial is testingAtlantic Lipid Lowering Treatment Optimization ProgramWho this might be right forFamilial HypercholesterolemiaLipoprotein Types--Lp System Lp(A) HyperlipoproteinemiaApolipoprotein B 100, Familial Defective+2 more Atlantic Health System 250
Large-scale testing (Phase 3)Study completedNCT02585895What this trial is testingEvolocumab Compared to LDL-C Apheresis in Patients Receiving LDL-C Apheresis Prior to Study EnrollmentWho this might be right forHypercholesterolemia Amgen 39
Early research (Phase 1)Study completedNCT05905068What this trial is testingAdult Subjects With Elevated Low-Density Lipoprotein-Cholesterol to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic EffectsWho this might be right forTo Reduce the LDL-C Level in Hypercholesteremia Adult PatientsCombination for Subgroup High LDL-c Patients With Other Comorbidities Ikaria Bioscience Pty Ltd 32
Testing effectiveness (Phase 2)Study completedNCT00327002What this trial is testingA Mechanistic Study of the Effects of LY518674 on High-Density Lipoprotein Cholesterol (HDL-C) MetabolismWho this might be right forMetabolic Syndrome X University of Pennsylvania 40
Not applicableStudy completedNCT00918918What this trial is testingEffect of Alcohol Consumption on Markers of InflammationWho this might be right forAlcohol ConsumptionInflammation TNO 24
Large-scale testing (Phase 3)Active Not RecruitingNCT06292013What this trial is testingInvestigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)Who this might be right forAtherosclerotic Cardiovascular Disease (ASCVD)Elevated Lp(a) Eli Lilly and Company 17,300
Testing effectiveness (Phase 2)Looking for participantsNCT07172646What this trial is testingSRSD216 in Patients With Elevated Lipoprotein (a)Who this might be right forHyperlipoproteinemia (a) Sirius Therapeutics Co., Ltd. 84
Large-scale testing (Phase 3)Study completedNCT00080275What this trial is testingEvaluation of the Safety & Efficacy of a Combination of Niacin ER & Simvastatin in Patients With Dyslipidemia (OCEANS)Who this might be right forHypercholesterolemia Kos Pharmaceuticals 600
Not applicableStudy completedNCT01333436What this trial is testingEvaluate Fasting/Postprandial Serum Apolipoprotein B-48 (ApoB-48) Levels in Diabetic Participants With Normal to Moderately High Low Density Lipoprotein-C (LDL-C) Levels (MK-0653A-259 AM1)Who this might be right forDyslipidemiaHypercholesterolemia Organon and Co 93
Large-scale testing (Phase 3)Ended earlyNCT01335997What this trial is testingEfficacy and Safety of Extended-Release Niacin/ Laropiprant/Simvastatin Tablets in Participants With Hypercholesterolemia or Mixed Dyslipidemia (MK-0524B-143)Who this might be right forPrimary HypercholesterolemiaMixed Dyslipidemia Merck Sharp & Dohme LLC 1,139
Post-approval studies (Phase 4)Ended earlyNCT01025492What this trial is testingStudy of Trilipix Effects on Lipids and ArteriesWho this might be right forDyslipidemia University of Utah 24
Large-scale testing (Phase 3)Study completedNCT00092625What this trial is testingCo-administration Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-803)Who this might be right forHypercholesterolemiaCoronary Disease Organon and Co 442
Not applicableWithdrawnNCT04993664What this trial is testingInfluence of Pelacarsen on Patients After Myocardial Infarction With High Lp(a) Values (PEMILA)Who this might be right forAcute Coronary SyndromeLipoproteinemiaInflammation+1 more University Medical Centre Ljubljana
Testing effectiveness (Phase 2)Study completedNCT05563246What this trial is testingLY3473329 in Adult Participants With Elevated Lipoprotein(a) at High Risk for Cardiovascular EventsWho this might be right forLipoprotein Disorder Eli Lilly and Company 233
Testing effectiveness (Phase 2)Study completedNCT05537571What this trial is testingEvaluate SLN360 in Participants With Elevated Lipoprotein(a) at High Risk of Atherosclerotic Cardiovascular Disease EventsWho this might be right forCardiovascular DiseasesAtherosclerosisLipoprotein(a) Silence Therapeutics plc 180
Large-scale testing (Phase 3)Looking for participantsNCT06597006What this trial is testingStudy to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial HypercholesterolemiaWho this might be right forFamilial Hypercholesterolemia - Homozygous Novartis Pharmaceuticals 9
Not applicableLooking for participantsNCT06995183What this trial is testingHeart CT Imaging to Detect Early Coronary Artery Disease in First-Degree Relatives With High or Low Lipoprotein(a) Identified Through Family ScreeningWho this might be right forLipoprotein(a) E.S.stroes 150
Not applicableNot Yet RecruitingNCT07720934What this trial is testingA Pilot Study to Investigate Platelet Reactivity in Patients With Elevated Lipoprotein(a) and Its Response to Antiplatelet TherapyWho this might be right forCardiovascular Prevention François MACH 60