Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Endothelin”

125 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 125 results

Testing effectiveness (Phase 2)Looking for participantsNCT06887062
What this trial is testing

Dapagliflozin and Endothelin Receptor Antagonism in Large Vessel Vasculitis (DERAIL-LVV)

Who this might be right for
Large Vessel VasculitisGiant Cell Arteritis (GCA)Takayasu Arteritis
University of Edinburgh 60
Testing effectiveness (Phase 2)Study completedNCT00817037
What this trial is testing

Sitaxsentan in Proteinuric Chronic Kidney Disease

Who this might be right for
Chronic Kidney DiseaseProteinuriaBlood Pressure
University of Edinburgh 27
Not applicableStudy completedNCT00745693
What this trial is testing

The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin

Who this might be right for
Coronary Disease
University of Edinburgh 15
Not applicableLooking for participantsNCT03404258
What this trial is testing

ET1 Concentration, Metabolic Pathway Activation, and Pulmonary Blood Flow in Infants Undergoing Superior Cavo-Pulmonary Anastomosis

Who this might be right for
Single-ventriclePulmonary Vascular Resistance AbnormalitySuperior Cavo-Pulmonary Anastomosis+2 more
University of Colorado, Denver 50
Large-scale testing (Phase 3)Looking for participantsNCT06819826
What this trial is testing

SC0062 Capsule for the Treatment of IgA Nephropathy with Proteinuria

Who this might be right for
IgA Nephropathy (IgAN)
Biocity Biopharmaceutics Co., Ltd. 360
Post-approval studies (Phase 4)Study completedNCT05373108
What this trial is testing

Endothelin-1 and Cardiac Allograft Vasculopathy (CAV)

Who this might be right for
Cardiac Allograft Vasculopathy
University of California, Los Angeles 19
Testing effectiveness (Phase 2)Study completedNCT00738049
What this trial is testing

Darusentan Effect on PET Uptake Heterogeneity

Who this might be right for
Coronary Artery DiseaseEndothelial Dysfunction
K.Lance Gould 40
Testing effectiveness (Phase 2)UnknownNCT04450095
What this trial is testing

Effects of Endothelin Receptor Antagonist on Ischemic Kidney Injury During Nephron Sparing Surgery

Who this might be right for
Kidney Failure, Acute
Bnai Zion Medical Center 30
Post-approval studies (Phase 4)UnknownNCT00637065
What this trial is testing

Bosentan in Pulmonary Hypertension in Interstitial Lung Disease Treatment Study

Who this might be right for
Pulmonary HypertensionInterstitial Lung DiseaseIdiopathic Pulmonary Fibrosis+1 more
Royal Brompton & Harefield NHS Foundation Trust 48
Not applicableStudy completedNCT02565030
What this trial is testing

Chronic Thrombo-embolic Pulmonary Hypertension: Classification and Long Term Outcome

Who this might be right for
Chronic Thromboembolic Pulmonary HypertensionIdiopathic Pulmonary Arterial Hypertension
Sheffield Teaching Hospitals NHS Foundation Trust 1,200
Not applicableStudy completedNCT02484807
What this trial is testing

Effect of Pharmacologic Interaction Between ERAs and PDE-5 Inhibitors on Medication Serum Levels and Clinical Disease Status in Patients With PAH

Who this might be right for
Pulmonary Arterial Hypertension
Heidelberg University 125
Large-scale testing (Phase 3)Study completedNCT00617669
What this trial is testing

A Phase III Trial of ZD4054 (Zibotentan) (Endothelin A Antagonist) and Docetaxel in Metastatic Hormone Resistant Prostate Cancer

Who this might be right for
Prostate Cancer
AstraZeneca 1,494
Not applicableWithdrawnNCT00593905
What this trial is testing

Pharmacogenomics in Pulmonary Arterial Hypertension

Who this might be right for
Pulmonary Arterial HypertensionPulmonary HypertensionPAH WHO Group I
West Penn Allegheny Health System
Large-scale testing (Phase 3)Study completedNCT00325442
What this trial is testing

FREEDOM-C: Oral Treprostinil in Combination With an Endothelin Receptor Antagonist (ERA) and/or a Phosphodiesterase-5 (PDE-5) Inhibitor for the Treatment of Pulmonary Arterial Hypertension (PAH)

Who this might be right for
Pulmonary Hypertension
United Therapeutics 354
Testing effectiveness (Phase 2)Ended earlyNCT00926627
What this trial is testing

Safety and Efficacy Study of Bosentan in Progressive Pulmonary Sarcoidosis

Who this might be right for
SarcoidosisPulmonary Hypertension
Daniel Doberer 32
Not applicableStudy completedNCT03503084
What this trial is testing

Short-term Effects of Tai Chi Chuan Exercise on the Regulation of Lipid and Glucose Metabolisms and Endothelial Function

Who this might be right for
Physiological Effect of TCC on Glucose Metabolism
Changhua Christian Hospital 40
Not applicableUnknownNCT04732650
What this trial is testing

Real World Difference After Changing Medication From Nonselective to Selective Endothelin Receptor Antagonist in Stable Eisenmenger Syndrome

Who this might be right for
Eisenmenger Complex
Samsung Medical Center 40
Testing effectiveness (Phase 2)Study completedNCT00423592
What this trial is testing

Phase 2 Study of Ambrisentan for Liver Function Test Rescue in Pulmonary Arterial Hypertension

Who this might be right for
Pulmonary Hypertension
Gilead Sciences 36
Large-scale testing (Phase 3)Study completedNCT04047563
What this trial is testing

Efficacy of Sovateltide (PMZ-1620) in Patients of Acute Ischemic Stroke

Who this might be right for
Cerebral IschemiaCerebral InfarctionStroke, Acute
Pharmazz, Inc. 158
Post-approval studies (Phase 4)Study completedNCT00438503
What this trial is testing

Glucose in Dialysis Water in Diabetics With Chronic Renal Failure

Who this might be right for
Renal Failure, ChronicDiabetic Nephropathies
Regional Hospital Holstebro 18
Load More Results