Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Endothelins”

125 trials

Showing 20 of 125 results

Testing effectiveness (Phase 2)Study completedNCT00111085
What this trial is testing

Clazosentan in Preventing the Occurrence of Cerebral Vasospasm Following an Aneurysmal Subarachnoid Hemorrhage (aSAH)

Who this might be right for
Aneurysmal Subarachnoid Hemorrhage
Idorsia Pharmaceuticals Ltd. 413
Very early researchLooking for participantsNCT06811831
What this trial is testing

Evaluation of the Efficacy of MACitentan in the Treatment of CoronaryMICrovascular Angina (MACMIC)

Who this might be right for
Coronary Microvascular AnginaMacitentan
China-Japan Friendship Hospital 30
Testing effectiveness (Phase 2)Study completedNCT01424319
What this trial is testing

Reducing Residual Albuminuria in Subjects With Diabetes and Nephropathy With Atrasentan

Who this might be right for
Chronic Kidney DiseaseDiabetic Nephropathy
AbbVie (prior sponsor, Abbott) 58
Testing effectiveness (Phase 2)Study completedNCT00423592
What this trial is testing

Phase 2 Study of Ambrisentan for Liver Function Test Rescue in Pulmonary Arterial Hypertension

Who this might be right for
Pulmonary Hypertension
Gilead Sciences 36
Testing effectiveness (Phase 2)Study completedNCT04052737
What this trial is testing

PMZ-1620 (Sovateltide) in Mild to Moderate Alzheimer's Disease

Who this might be right for
Alzheimer DiseaseDementia
Pharmazz, Inc. 80
Not applicableActive Not RecruitingNCT03436238
What this trial is testing

Myocardial Injury in Noncardiac Surgery in Sweden

Who this might be right for
Perioperative/Postoperative ComplicationsRisk Factor, Cardiovascular
Linkoeping University 1,269
Testing effectiveness (Phase 2)Looking for participantsNCT06942910
What this trial is testing

Investigate the Effects of Zibotentan/Dapagliflozin Combination Compared to Dapagliflozin Alone in Adult Participants With Chronic Kidney Disease and High Proteinuria

Who this might be right for
Chronic Kidney Disease With High Proteinuria
AstraZeneca 224
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06072326
What this trial is testing

DApagliflozin SC0062 and Prevention of Renal Injury; a Randomized Evaluation

Who this might be right for
Type 1 Diabetes Mellitus With Diabetic Nephropathy
University Medical Center Groningen 36
Not applicableWithdrawnNCT02309463
What this trial is testing

Correlation of LONGterm Wrist ACTigraphy Recorded Physical Performance & 6-minute Walk Distance in Patients With Pulmonary Arterial Hypertension

Who this might be right for
Pulmonary Arterial Hypertension
Actelion
Testing effectiveness (Phase 2)Study completedNCT00817037
What this trial is testing

Sitaxsentan in Proteinuric Chronic Kidney Disease

Who this might be right for
Chronic Kidney DiseaseProteinuriaBlood Pressure
University of Edinburgh 27
Large-scale testing (Phase 3)Ended earlyNCT01884675
What this trial is testing

Ambrisentan for Inoperable Chronic Thromboembolic Pulmonary Hypertension.

Who this might be right for
Hypertension
GlaxoSmithKline 33
Large-scale testing (Phase 3)UnknownNCT03841734
What this trial is testing

Study of the Benefit of Early Treatment With an Endothelin Inhibitor (Bosentan) in Patients With Sudden Blindness Due to Giant Cell Arteritis: CECIBO

Who this might be right for
Arteritis, Giant CellBlindness and Low Vision
Centre Hospitalier Universitaire de Nice 8
Not applicableStudy completedNCT00814281
What this trial is testing

Airborne Ultrafine and Fine Particulate Matter: A Cause for Endothelial Dysfunction in Man?

Who this might be right for
Airway Inflammation
Marywood University 24
Testing effectiveness (Phase 2)Study completedNCT00586820
What this trial is testing

Role of Endothelin in Microvascular Dysfunction Following PCI for NSTEMI

Who this might be right for
Myocardial Reperfusion Injury
Mayo Clinic 23
Testing effectiveness (Phase 2)Study completedNCT01241383
What this trial is testing

Effect of Bosentan in Scleroderma Renal Crisis

Who this might be right for
Scleroderma Renal Crisis
Assistance Publique - Hôpitaux de Paris 16
Not applicableStudy completedNCT00001527
What this trial is testing

Role of Endothelin in the Regulation of Vascular Tone in Patients With Essential Hypertension

Who this might be right for
Hypertension
National Heart, Lung, and Blood Institute (NHLBI) 60
Testing effectiveness (Phase 2)WithdrawnNCT00406731
What this trial is testing

Role of Endothelin- and Nitric Oxide-system in the Regulation of Optic Nerve Head Blood Flow During Changes in Ocular Perfusion Pressure

Who this might be right for
Ocular PhysiologyOptic DiskRegional Blood Flow
Medical University of Vienna
Testing effectiveness (Phase 2)Study completedNCT00522925
What this trial is testing

A Trial to Evaluate the Safety and Efficacy of PS433540 to Treat Hypertension

Who this might be right for
Hypertension
Ligand Pharmaceuticals 280
Large-scale testing (Phase 3)WithdrawnNCT00760916
What this trial is testing

FREEDOM DR: Oral Treprostinil in Combination With an Endothelin Receptor Antagonist (ERA) and/or a Phosphodiesterase-5 (PDE-5) Inhibitor or as Monotherapy for the Treatment of Pulmonary Arterial Hypertension (PAH)

Who this might be right for
Pulmonary Hypertension
United Therapeutics
Testing effectiveness (Phase 2)Study completedNCT01890135
What this trial is testing

Zibotentan, an Endothelin Receptor Antagonist, Patients With Intermittent Claudication

Who this might be right for
Peripheral Arterial DiseaseIntermittent Claudication
University of Virginia 31
Load More Results

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation