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Results for “Enzyme Deficiency”

72 trials

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Showing 20 of 72 results

Early research (Phase 1)Study completedNCT01554800
What this trial is testing

Effect of ACP-501 on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Subjects With Coronary Artery Disease

Who this might be right for
Coronary Artery DiseaseAtherosclerosis
MedImmune LLC 16
Not applicableStudy completedNCT04669106
What this trial is testing

Mineral and Enzyme Deficiency Diseases Associated With Nutritional Diseases in Society

Who this might be right for
Nutrient Deficiency
Universitas Sumatera Utara 180
Not applicableUnknownNCT05300373
What this trial is testing

Evaluation of Adenosine Deaminase (ADA) Enzyme Deficiency in Patients With Lymphopenia and/or Elevated Immunoglobulin E

Who this might be right for
Adenosine Deaminase Deficiency
TRPHARM 100
Large-scale testing (Phase 3)Study completedNCT00006327
What this trial is testing

Effectiveness of AIDSVAX B/E Vaccine in Intravenous Drug Users in Bangkok, Thailand

Who this might be right for
HIV InfectionsHIV Seronegativity
VaxGen 2,500
Large-scale testing (Phase 3)Study completedNCT00069641
What this trial is testing

Iduronate-2-sulfatase Enzyme Replacement Therapy in Mucopolysaccharidosis II (MPS II)

Who this might be right for
Mucopolysaccharidosis II
Shire 96
Post-approval studies (Phase 4)Study completedNCT02450487
What this trial is testing

Influence of Genotype of CYP2C9 on Clinical Efficacy and Pharmacokinetics of Piroxicam After Lower Third Molar Surgery

Who this might be right for
PainOther Surgical ProceduresImpacted Third Molar Tooth+1 more
University of Sao Paulo 105
Large-scale testing (Phase 3)Study completedNCT01757184
What this trial is testing

Acid Lipase Replacement Investigating Safety and Efficacy (ARISE) in Participants With Lysosomal Acid Lipase Deficiency

Who this might be right for
Lysosomal Acid Lipase Deficiency
Alexion Pharmaceuticals, Inc. 66
Not applicableStudy completedNCT02191358
What this trial is testing

YouScript IMPACT Registry

Who this might be right for
Adverse Drug EventsAdverse Drug ReactionsDrug Interaction Potentiation+10 more
Genelex Corporation 800
Testing effectiveness (Phase 2)Study completedNCT01307098
What this trial is testing

Safety, Tolerability and Pharmacokinetics of SBC-102 (Sebelipase Alfa) in Adult Participants With Lysosomal Acid Lipase Deficiency

Who this might be right for
Cholesterol Ester Storage Disease(CESD)Lysosomal Acid Lipase DeficiencyLAL-Deficiency
Alexion Pharmaceuticals, Inc. 9
Not applicableWithdrawnNCT00000804
What this trial is testing

Trial of L-735,524, An Inhibitor of the HIV Protease Enzyme, and Interleukin-2 in Persons Infected With HIV (NOTE: Only For Patients Who Previously Completed NIAID 93 CC-113)

Who this might be right for
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
Testing effectiveness (Phase 2)Looking for participantsNCT06199531
What this trial is testing

Safety and Efficacy of GS-100 Gene Therapy in Patients With NGLY1 Deficiency

Who this might be right for
NGLY1 Deficiency
Grace Science, LLC 6
Early research (Phase 1)Study completedNCT01881984
What this trial is testing

Use of Ravicti™ in Patients With MCAD Deficiency With the 985A>G (K304E) Mutation

Who this might be right for
Medium-chain Acyl-CoA Dehydrogenase (MCAD) Deficiency
University of Pittsburgh 4
Testing effectiveness (Phase 2)Looking for participantsNCT06887777
What this trial is testing

Efficacy and Safety of the Treatment of Pyruvate Dehydrogenase Deficiency Patients With Glycerol Phenylbutyrate (RAVICTI)

Who this might be right for
Pyruvate Dehydrogenase Complex Deficiency Disease
Assistance Publique - Hôpitaux de Paris 15
Not applicableStudy completedNCT01884220
What this trial is testing

Wolman/CESD Natural History Chart Review and Longitudinal Follow-Up

Who this might be right for
Wolman DiseaseCholesterol Ester Storage DiseaseAcid Cholesteryl Ester Hydrolase Deficiency, Type 2
Children's Hospital Medical Center, Cincinnati 4
Early research (Phase 1)Ended earlyNCT02795325
What this trial is testing

DCR-PH1 in Patients With Primary Hyperoxaluria Type 1 (PH1)

Who this might be right for
Primary Hyperoxaluria Type 1
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 41
Testing effectiveness (Phase 2)Study completedNCT00786422
What this trial is testing

Deep Vein Thrombosis Treatment With the Oral Direct Factor Xa Inhibitor Rivaroxaban in Patients Using a Strong CYP 3A4 Inducer

Who this might be right for
Venous ThrombosisDeep Vein Thrombosis
Bayer 25
Early research (Phase 1)Not Yet RecruitingNCT07354724
What this trial is testing

Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL952 in Adult Participants With Late-Onset Pompe Disease

Who this might be right for
Late-onset Pompe Disease
Denali Therapeutics Inc. 32
Testing effectiveness (Phase 2)UnknownNCT04011930
What this trial is testing

This Study Include Chronic Obstructive Pulmonary Disease(COPD) Patients . Patients Were Vitamin D Deficient Age Range 40 to 80 Years, Smokers Patients Were Advised to Take Either Placebo or Vitamin D3 . Antioxidant Enzymes Were Assessed at Baseline and at 26th Weeks.

Who this might be right for
Chronic Obstructive Pulmonary Disease
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 40
Testing effectiveness (Phase 2)Study completedNCT02112994
What this trial is testing

Safety and Efficacy Study of Sebelipase Alfa in Participants With Lysosomal Acid Lipase Deficiency

Who this might be right for
Lysosomal Acid Lipase Deficiency
Alexion Pharmaceuticals, Inc. 31
Not applicableStudy completedNCT00006064
What this trial is testing

The Effect of Anti-HIV Treatment on Body Characteristics of HIV-Infected Children

Who this might be right for
HIV InfectionsHIV Wasting SyndromeLipodystrophy
National Institute of Allergy and Infectious Diseases (NIAID) 100
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