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Results for “Enzyme Deficiency”

72 trials

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Showing 20 of 72 results

Early research (Phase 1)Study completedNCT01554800
What this trial is testing

Effect of ACP-501 on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Subjects With Coronary Artery Disease

Who this might be right for
Coronary Artery DiseaseAtherosclerosis
MedImmune LLC 16
Not applicableStudy completedNCT04403932
What this trial is testing

Increased Risk of Severe Coronavirus Disease 2019 in Patients With Vitamin D Deficiency

Who this might be right for
Coronavirus Disease 2019 (COVID-19)
Hospital San Carlos, Madrid 300
Testing effectiveness (Phase 2)Looking for participantsNCT06475352
What this trial is testing

Dose Individualization of Chemotherapy in Patients With Gastrointestinal Cancers Lacking a Specific Liver Enzyme

Who this might be right for
Digestive CancerColorectal Cancer
UNICANCER 400
Post-approval studies (Phase 4)Study completedNCT03204578
What this trial is testing

Physiological Study of the Human CYP3A Activity (PiSA)

Who this might be right for
Cytochrome P450 CYP3A Enzyme Deficiency
University Hospital, Basel, Switzerland 12
Large-scale testing (Phase 3)Study completedNCT01414374
What this trial is testing

Hibiscus Sabdariffa and Centella Asiatica in the Treatment of Anemia by Iron Deficiency

Who this might be right for
Iron Deficiency Anemia
Casa Espirita Terra de Ismael 50
Testing effectiveness (Phase 2)Study completedNCT00947960
What this trial is testing

Triheptanoin Treatment Trial for Patients With Adult Polyglucosan Body Disease

Who this might be right for
Adult Polyglucosan Body DiseaseGlycogen Brancher Enzyme DeficiencyGlycogen Storage Disease Type IV
Baylor Research Institute 23
Not applicableUnknownNCT05300334
What this trial is testing

Investigation of ADA Enzyme Deficiency

Who this might be right for
Adenosine Deaminase Deficiency
TRPHARM 800
Early research (Phase 1)Study completedNCT01289756
What this trial is testing

Influence of Pharmacogenetic Factors, Paroxetine and Clarithromycin on Pharmacokinetics of Clomiphene

Who this might be right for
AnovulationDisorder Due Cytochrome P450 CYP2D6 VariantCytochrome P450 CYP3A Enzyme Deficiency
Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF) 20
Not applicableStudy completedNCT01884220
What this trial is testing

Wolman/CESD Natural History Chart Review and Longitudinal Follow-Up

Who this might be right for
Wolman DiseaseCholesterol Ester Storage DiseaseAcid Cholesteryl Ester Hydrolase Deficiency, Type 2
Children's Hospital Medical Center, Cincinnati 4
Early research (Phase 1)Ended earlyNCT02795325
What this trial is testing

DCR-PH1 in Patients With Primary Hyperoxaluria Type 1 (PH1)

Who this might be right for
Primary Hyperoxaluria Type 1
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 41
Not applicableLooking for participantsNCT07088302
What this trial is testing

Effect OF Lactase Enzyme Supplements ON Intolerance IN Preterm Neonates

Who this might be right for
PrematureFeeding DisordersLactase Deficiency, Congenital
Alexandria University 120
Not applicableStudy completedNCT02360644
What this trial is testing

Drug Metabolizing Enzyme and Transporter Function in Chronic Kidney Disease

Who this might be right for
Chronic Kidney DiseasesDeficiency, Vitamin D
University of Colorado, Denver 23
Not applicableStudy completedNCT00555633
What this trial is testing

Use of an SPF30 Sunscreen and an After-sun-lotion in Skin Cancer Risk Patients

Who this might be right for
Skin CancerXeroderma PigmentosumBasal Cell Nevus Syndrome
Medical University of Graz 13
Not applicableStudy completedNCT02276014
What this trial is testing

Effect of SNPs in the BCMO1 Enzyme

Who this might be right for
Beta-carotene BioavailabilityVitamin A Deficiency
Newcastle-upon-Tyne Hospitals NHS Trust 85
Not applicableUnknownNCT05300360
What this trial is testing

Prevalence of Adenosine Deaminase (ADA) Enzyme Deficiency Disease in Adult Patients With Pulmonary Alveolar Proteinosis

Who this might be right for
Pulmonary Alveolar Proteinosis
TRPHARM 15
Not applicableUnknownNCT03931889
What this trial is testing

Effects of Vitamin D3 Supplementation on Antioxidant Enzymes Status in Vitamin D3 Deficient Asthma COPD Overlap (ACO) Patients

Who this might be right for
Vitamin D Deficiency
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 40
Testing effectiveness (Phase 2)Study completedNCT01488097
What this trial is testing

Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of SBC-102 (Sebelipase Alfa) in Adult Subjects With Lysosomal Acid Lipase Deficiency

Who this might be right for
Cholesterol Ester Storage Disease (CESD)Lysosomal Acid Lipase DeficiencyLAL-Deficiency
Alexion Pharmaceuticals, Inc. 8
Not applicableStudy completedNCT02378220
What this trial is testing

Pharmacogenetic Testing Among Home Health Patients

Who this might be right for
Adverse Drug EventsAdverse Drug ReactionsDrug Interaction Potentiation+10 more
Genelex Corporation 110
Not applicableLooking for participantsNCT06213402
What this trial is testing

RADeep Multicenter European Epidemiological Platform for Patients Diagnosed With Rare Anemia Disorders (RADs)

Who this might be right for
Sickle Cell DiseaseThalassemiaHemolytic; Anemia, Hereditary, Due to Enzyme Disorder+6 more
Hospital Universitari Vall d'Hebron Research Institute 32,564
Testing effectiveness (Phase 2)Study completedNCT00005931
What this trial is testing

SU5416 in Patients With AIDS-Related Kaposi's Sarcoma Who Have Not Responded to Treatment

Who this might be right for
Sarcoma, KaposiHIV Infections
SUGEN 30
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