Large-scale testing (Phase 3)UnknownNCT04651439What this trial is testingSevere Bullous Drug Eruption and FilgrastimWho this might be right forRare DiseasesToxic Epidermal Necrolyses Hospices Civils de Lyon 42
Not applicableWithdrawnNCT02795143What this trial is testingEvaluating the Effect of Isotretinoin in Regulatory T-cell Function in Adverse Cutaneous Drug Eruptions (ACDEs): A Pilot StudyWho this might be right forToxic Epidermal Necrolysis Massachusetts General Hospital
Testing effectiveness (Phase 2)WithdrawnNCT02319616What this trial is testingTopical Clobetasol for the Treatment of Toxic Epidermal NecrolysisWho this might be right forToxic Epidermal Necrolysis University of California, Davis
Testing effectiveness (Phase 2)WithdrawnNCT02126020What this trial is testingTopical Infliximab in Autoimmune Eyes With KeratoprosthesisWho this might be right forStevens-Johnson SyndromeToxic Epidermal Necrolysis (Lyell) SyndromeMucous Membrane Pemphigoid James Chodosh, MD, MPH
Testing effectiveness (Phase 2)Looking for participantsNCT04711200What this trial is testingLYell SYndrome MEsenchymal Stromal Cells TreatmentWho this might be right forEpidermal NecrolysisLyell SyndromeToxic Epidermal Necrolysis+3 more Assistance Publique - Hôpitaux de Paris 15
Not applicableUnknownNCT03839069What this trial is testingMinor Salivary Gland Transplantation for Cicatrizing ConjunctivitisWho this might be right forCicatrizing ConjunctivitisStevens-Johnson Syndrome Toxic Epidermal Necrolysis SpectrumSjogren Syndrome+3 more National Taiwan University Hospital 30
Not applicableStudy completedNCT06522048What this trial is testingSJS/TEN or Other Cutaneous Adverse Eevents Induced by Immune Checkpoint Inhibitors (ICIs) vs. Non-ICIsWho this might be right forImmune Checkpoint Inhibitor-Induced DermatitisStevens-Johnson Syndrome, Drug-InducedToxic Epidermal Necrolysis Due to Drug Chao Ji 300
Testing effectiveness (Phase 2)Ended earlyNCT02037347What this trial is testingStudy to Evaluate the Use of Palifermin to Treat Toxic Epidermal NecrolysisWho this might be right forToxic Epidermal NecrolysisStevens-Johnson Syndrome Brett King 1
Post-approval studies (Phase 4)Not Yet RecruitingNCT07369622What this trial is testingHLA-B*58:01-Guided Therapy for Gout: Effectiveness, Safety, and Cost-EffectivenessWho this might be right forGout Initiating Urate-loweringUrate-lowering TherapyGout ArthritisGout and Hyperuricemia Haiphong University of Medicine and Pharmacy 228
Not applicableWithdrawnNCT03585946What this trial is testingOutcomes in Stevens Johnsons Syndrome and Toxic Epidermal NecrolysisWho this might be right forStevens-Johnson SyndromeToxic Epidermal NecrolysisDrug Reaction Massachusetts General Hospital
Not applicableUnknownNCT02574988What this trial is testingSevere Cutaneous Adverse Reactions in ThailandWho this might be right forSteven-Johnson SyndromeToxic Epidermal NecrolysisDrug Reaction With Eosinophilia and Systemic Symptoms+2 more Chulalongkorn University 200
Testing effectiveness (Phase 2)WithdrawnNCT01256489What this trial is testingInfliximab to Improve Retention of the Boston Keratoprosthesis in Patients After Stevens Johnson Syndrome/ Toxic Epidermal Necrolysis (SJS/TENS)Who this might be right forStevens-Johnson SyndromeCorneal Blindness Massachusetts Eye and Ear Infirmary
Testing effectiveness (Phase 2)WithdrawnNCT00372723What this trial is testingStudy of a Potential New Treatment for Patients With Toxic Epidermal Necrolysis (TEN)Who this might be right forToxic Epidermal Necrolysis Loyola University
Not applicableStudy completedNCT06474078What this trial is testingStudy To Evaluate The Efficacy Of Tofacitinib In Patients With SJS/TENWho this might be right forStevens-Johnson SyndromeToxic Epidermal Necrolysis Chang Gung Memorial Hospital 20
Not applicableUnknownNCT04252651What this trial is testingAssociation of Cytokines With the Development of Complications in Burn and Toxic Epidermal Necrolysis (TENS) PatientsWho this might be right forInflammatory ResponseMulti Organ FailureNosocomial Infection+1 more Joseph M. Still Research Foundation, Inc. 65
Post-approval studies (Phase 4)Study completedNCT02739295What this trial is testingG-CSF in the Treatment of Toxic Epidermal NecrolysisWho this might be right forStevens - Johnson Syndrome University of Liege 10
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07110662What this trial is testingNew Therapeutic Target for Toxic Epidermal Necrolysis (TEN) Using Anti-CD38+ Monoclonal Antibodies.Who this might be right forToxic Epidermal NecrolysisImmunotherapyCutaneous Adverse Drug Reactions (CADR) Hospices Civils de Lyon 9
Large-scale testing (Phase 3)Study completedNCT01696500What this trial is testingPhase III Clinical Trial of NPB-01 in Patients With Stevens-Johnson Syndrome/ Toxic Epidermal Necrolysis Unresponsive to Corticosteroids.Who this might be right forStevens-Johnson SyndromeToxic Epidermal Necrolysis Nihon Pharmaceutical Co., Ltd 10
Not applicableUnknownNCT05145959What this trial is testingMeibomian Gland Probing in the Sub-Acute Phase of Patients With Stevens-Johnson Syndrome/Toxic Epidermal NecrolysisWho this might be right forStevens-Johnson SyndromeToxic Epidermal NecrolysesOcular Surface Disease+3 more Massachusetts Eye and Ear Infirmary 30
Very early researchLooking for participantsNCT06119490What this trial is testingEvaluation of the Efficacy and Safety of Methylprednisolone Combined With the JAK Inhibitors in the Treatment of Toxic Epidermal NecrolysisWho this might be right forToxic Epidermal Necrolysis Peng Zhang 30