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Results for “Epidermolysis Bullosa Dystrophica, Recessive”

48 trials

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Showing 20 of 48 results

Early research (Phase 1)Study completedNCT02493816
What this trial is testing

Safety Study of Gene-modified Autologous Fibroblasts in Recessive Dystrophic Epidermolysis Bullosa

Who this might be right for
Recessive Dystrophic Epidermolysis Bullosa
King's College London 5
Early research (Phase 1)Active Not RecruitingNCT06713434
What this trial is testing

Pilot Study of ELK-003 Eye Drops for Treating Ocular Manifestations of Epidermolysis Bullosa

Who this might be right for
Junctional Epidermolysis BullosaEpidermolysis Bullosa (EB)Dystrophic Epidermolysis Bullosa+1 more
Fundación DEBRA Chile, Niños Piel de Cristal 20
Not applicableEnrolling By InvitationNCT05708677
What this trial is testing

A Long-Term Extension Study for Participants Previously Treated With EB-101 for the Treatment of RDEB

Who this might be right for
RDEB
Abeona Therapeutics, Inc 22
Not applicableLooking for participantsNCT06563414
What this trial is testing

A Natural History Study of Corneal Abrasions in Patients With Dystrophic Epidermolysis Bullosa (DEB)

Who this might be right for
Epidermolysis Bullosa DystrophicaEpidermolysis Bullosa Dystrophica, RecessiveEpidermolysis Bullosa Dystrophica Dominans
Krystal Biotech, Inc. 40
Very early researchStudy completedNCT04177498
What this trial is testing

Rigosertib in Patients With Recessive Dystrophic Epidermolysis Bullosa Associated SCC

Who this might be right for
Recessive Dystrophic Epidermolysis Bullosa
Thomas Jefferson University 3
Testing effectiveness (Phase 2)Study completedNCT03786237
What this trial is testing

Rigosertib for RDEB-SCC

Who this might be right for
Epidermolysis Bullosa DystrophicaSquamous Cell Carcinoma
Prof. Johann Bauer 2
Not applicableUnknownNCT04285294
What this trial is testing

Molecular Signatures of Cutaneous Squamous Cell Carcinoma During Recessive Dystrophic Epidermolysis Bullosa

Who this might be right for
Recessive Dystrophic Epidermolysis Bullosa
Assistance Publique - Hôpitaux de Paris 66
Testing effectiveness (Phase 2)Looking for participantsNCT07193134
What this trial is testing

GMEB-SASS: A Gene-Modified Skin Substitute for RDEB Treatment

Who this might be right for
RDEBRecessive Dystrophic Epidermolysis BullosaEpidermolysis Bullosa Dystrophica, Recessive
CHU de Quebec-Universite Laval 9
Not applicableStudy completedNCT00904163
What this trial is testing

Characteristics of Adult Patients With Recessive Dystrophic Epidermolysis Bullosa

Who this might be right for
Epidermolysis Bullosa Dystrophica
Stanford University 13
Testing effectiveness (Phase 2)Study completedNCT02698735
What this trial is testing

Gentamicin Therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB) Nonsense Mutation Patients

Who this might be right for
Recessive Dystrophic Epidermolysis Bullosa
University of Southern California 5
Testing effectiveness (Phase 2)Looking for participantsNCT06834035
What this trial is testing

Targeting Collagen VII Antibodies With IV IgG in Dystrophic Epidermolysis Bullosa

Who this might be right for
Epidermolysis BullosaEpidermolysis Bullosa AcquisitaDystrophic Epidermolysis Bullosa+1 more
M. Peter Marinkovich 8
Not applicableLooking for participantsNCT04917887
What this trial is testing

Long-Term Follow-up Protocol

Who this might be right for
Dystrophic Epidermolysis BullosaRecessive Dystrophic Epidermolysis BullosaDominant Dystrophic Epidermolysis Bullosa
Krystal Biotech, Inc. 50
Not applicableStudy completedNCT05944250
What this trial is testing

A Pilot Study to Evaluate a Temporary Skin Substitute (Spincare® Matrix) for Wound Healing in RDEB Patients

Who this might be right for
Recessive Dystrophic Epidermolysis Bullosa
Stanford University 6
Testing effectiveness (Phase 2)Ended earlyNCT02984085
What this trial is testing

Clinical Trial to Assess Safety and Efficacy of Autologous Cultured Epidermal Grafts Containing Epidermal Stem Cells Genetically Modified in Patients With RDEB.

Who this might be right for
Recessive Dystrophic Epidermolysis Bullosa
Holostem s.r.l. 3
Testing effectiveness (Phase 2)Ended earlyNCT03605069
What this trial is testing

A Double-blind, Randomized, Intra-subject Placebo-controlled, Multicenter, Multiple Dose Study, Evaluating Safety, Proof of Mechanism, Preliminary Efficacy and Systemic Exposure in Subjects With Confirmed DDEB or RDEB Diagnosis With One or More Pathogenic Mutations in Exon 73 in the COL7A1 Gene

Who this might be right for
Epidermolysis Bullosa Dystrophica, RecessiveEpidermolysis Bullosa Dystrophica, Dominant
Phoenicis Therapeutics 2
Not applicableLooking for participantsNCT06177353
What this trial is testing

Study of the Blood and Skin Immunological Profile of Patients With Recessive Dystrophic Epidermolysis Bullosa: in Vivo Analysis and the Impact of Placental Stem Cells in Vitro

Who this might be right for
Epidermolysis Bullosa Dystrophica
Assistance Publique - Hôpitaux de Paris 30
Large-scale testing (Phase 3)Looking for participantsNCT07016750
What this trial is testing

A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa

Who this might be right for
Dystrophic Epidermolysis BullosaDEB - Dystrophic Epidermolysis BullosaRecessive Dystrophic Epidermolysis Bullosa+1 more
Krystal Biotech, Inc. 16
Early research (Phase 1)Study completedNCT00014729
What this trial is testing

Phase I Study of Isotretinoin in Patients With Recessive Dystrophic Epidermolysis Bullosa

Who this might be right for
Epidermolysis Bullosa
University of North Carolina 20
Large-scale testing (Phase 3)Study completedNCT04491604
What this trial is testing

Ph 3 Efficacy and Safety of B-VEC for the Treatment of DEB

Who this might be right for
Dystrophic Epidermolysis BullosaRecessive Dystrophic Epidermolysis BullosaDominant Dystrophic Epidermolysis Bullosa
Krystal Biotech, Inc. 31
Not applicableStudy completedNCT01874769
What this trial is testing

Study of Immune Tolerance and Capacity for Wound Healing of Patients With Recessive Dystrophic Epidermolysis Bullosa (RDEB)

Who this might be right for
Recessive Dystrophic Epidermolysis Bullosa
Institut National de la Santé Et de la Recherche Médicale, France 30
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