Not applicableStudy completedNCT06432322What this trial is testing(GluEsk) Glutamate and EsketamineWho this might be right forDepression University of Oxford 16
Early research (Phase 1)Study completedNCT01780259What this trial is testingAssess the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine in Healthy ParticipantsWho this might be right forHealthy Janssen Research & Development, LLC 58
Early research (Phase 1)Study completedNCT06726382What this trial is testingKF2024#1-trial: Esketamine Interaction StudyWho this might be right forDrug InteractionsFood-drug Interaction Helsinki University Central Hospital 12
Not applicableUnknownNCT06473285What this trial is testingEffects of Esketamine on Consciousness-related Brain Network Characteristics in Patients With Prolonged Disorders of ConsciousnessWho this might be right forProlonged Disorders of Consciousness Beijing Tiantan Hospital 80
Not applicableUnknownNCT04643132What this trial is testingS-ketamine Prevents Postoperative Pain and Cognitive Dysfunction After Tibial FractureWho this might be right forPostoperative PainPostoperative Cognitive Dysfunction Tianjin Medical University General Hospital 120
Not applicableNot Yet RecruitingNCT06914193What this trial is testingEsketamine Combined With PRF of DRG for Postherpetic NeuralgiaWho this might be right forPostherpetic Neuralgia Beijing Tiantan Hospital 186
Large-scale testing (Phase 3)Study completedNCT04338321What this trial is testingA Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive DisorderWho this might be right forDepressive Disorder, Major Janssen-Cilag International NV 676
Not applicableStudy completedNCT04760652What this trial is testingCognitive Behavioral Therapy Following Esketamine for Major Depression and Suicidal Ideation for Relapse PreventionWho this might be right forDepression and Suicide Yale University 93
Not applicableStudy completedNCT06530706What this trial is testingEffect of Esketamine on Anxiety State in Patients Undergoing Abdominal Tumor SurgeryWho this might be right forAnxiety StateEsketamine Zhejiang Cancer Hospital 185
Not applicableStudy completedNCT05060068What this trial is testingEffect of Intravenous S-ketamine on Opioid ConsumptionWho this might be right forBreast Cancer Surgery The Second Hospital of Anhui Medical University 345
Not applicableStudy completedNCT06658132What this trial is testingA General Anesthesia Regimen for DBS Surgery in Patients With PDWho this might be right forParkinson's Disease (PD) RenJi Hospital 20
Post-approval studies (Phase 4)WithdrawnNCT02397356What this trial is testingInhaled Nebulised S(+)-Ketamine for Postoperative AnalgesiaWho this might be right forPain, Postoperative Tampere University Hospital
Not applicableEnrolling By InvitationNCT07125573What this trial is testingThe Effect of Esketamine Combined With Dexmedetomidine on Postoperative Recovery Quality in Patients Undergoing Thoracoscopic SurgeryWho this might be right forEsketamine Plus Dexmedetomidine Affect Postoperative QualityThoracoscopyLung Neoplasms First Affiliated Hospital of Kunming Medical University 120
Early research (Phase 1)Study completedNCT02060929What this trial is testingEvaluate the Pharmacokinetics of Intranasal Esketamine Administered With and Without a Nasal Guide on the Intranasal DeviceWho this might be right forHealthy Janssen Research & Development, LLC 14
Early research (Phase 1)Study completedNCT02129088What this trial is testingA Pharmacokinetic, Safety and Tolerability Study of Esketamine in Healthy Elderly and Adult ParticipantsWho this might be right forHealthy Janssen Research & Development, LLC 34
Post-approval studies (Phase 4)Active Not RecruitingNCT05698394What this trial is testingEffect of Low-dose Esketamine on Maternal Depression at 3 Years After ChildbirthWho this might be right forPrenatal DepressionKetaminePostpartum Depression Peking University First Hospital 364
Not applicableUnknownNCT04843462What this trial is testingAdd-on Therapy With Edupression.Com® on Therapy Resistant Depressive Patients Treated With Nasal Esketamine SprayWho this might be right forMajor Depressive DisorderTherapy Resistant Depression Lukas Pezawas 70
Post-approval studies (Phase 4)Study completedNCT02994173What this trial is testingDose-response of Ketamine in Patient Controlled Analgesia in Orthopaedic Surgery PatientsWho this might be right forPain, Postoperative Turku University Hospital 100
Post-approval studies (Phase 4)Study completedNCT00354029What this trial is testingEffect of Perioperative i.v. Low-dose S(+) KetamineWho this might be right forHemorrhoidsPain Asker & Baerum Hospital 83
Post-approval studies (Phase 4)Study completedNCT05458453What this trial is testingAn Exploratory Study of Esketamine in Patients After Thoracoscopic SurgeryWho this might be right forEsketamineThoracoscopic Surgery The Second Affiliated Hospital of Chongqing Medical University 80