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Results for “Extensive Metabolizers”

16 trials

Showing 16 of 16 results

Early research (Phase 1)Study completedNCT00766025
What this trial is testing

Study in Taiwanese Subjects Identified as CYP2C19 Poor and Extensive Metabolizers Receiving Rosuvastatin

Who this might be right for
CYP2C19 PoorExtensive Metabolizers
AstraZeneca 50
Early research (Phase 1)Study completedNCT01367535
What this trial is testing

Effects of MNTX on CYP450 2D6 in Metabolizers of Dextromethorphan

Who this might be right for
Healthy Adults
Bausch Health Americas, Inc. 54
Early research (Phase 1)Study completedNCT04619251
What this trial is testing

A Study in Healthy Japanese Men to Test How Different Doses of BI 1323495 Are Tolerated and How Itraconazole Influences the Amount of BI 1323495 in the Blood

Who this might be right for
Healthy
Boehringer Ingelheim 74
Early research (Phase 1)Study completedNCT02248259
What this trial is testing

Drug Drug Interaction Trial With Strong CYP3A4 Inhibitor (Itraconazole) in CYP2C19 Extensive Metabolizers and Poor Metabolizers

Who this might be right for
Healthy
Boehringer Ingelheim 25
Early research (Phase 1)Study completedNCT01478490
What this trial is testing

To Compare Blood and Urine Concentrations of Mirabegron (YM178) in Healthy Poor or Extensive Metabolizers for CYP2D6 and to Assess the Effect of Mirabegron on the Metabolism of Metoprolol

Who this might be right for
Pharmacokinetics of MirabegronHealthy Subjects
Astellas Pharma Inc 28
Early research (Phase 1)Study completedNCT02264171
What this trial is testing

Study to Investigate the Effect of Ketoconazole Mediated CYP3A4 Inhibition on Pharmacokinetics of Tamsulosin in Healthy Male Volunteers

Who this might be right for
Healthy
Boehringer Ingelheim 24
Early research (Phase 1)Study completedNCT00727064
What this trial is testing

Study Evaluating the Pharmacokinetics of Venlafaxine Extended-Release (ER) and Desvenlafaxine Succinate Sustained-Release (DVS SR) 50 mg in Healthy Subjects

Who this might be right for
Healthy
Wyeth is now a wholly owned subsidiary of Pfizer 14
Early research (Phase 1)Study completedNCT02264184
What this trial is testing

Study to Investigate the Effect of Paroxetine Mediated CYP2D6 Inhibition on the Pharmacokinetics of Tamsulosin in Healthy Male Volunteers

Who this might be right for
Healthy
Boehringer Ingelheim 24
Early research (Phase 1)Study completedNCT06188325
What this trial is testing

Evaluate Pharmacokinetic Parameters of Eliglustat in Healthy Volunteers Who Are CYP2D6 Extensive or Poor Metabolizers

Who this might be right for
Gaucher's Disease
Sanofi 18
Large-scale testing (Phase 3)Study completedNCT00329186
What this trial is testing

Study Evaluating the Pharmacokinetics of Venlafaxine ER and Desvenlafaxine SR in Healthy Subjects

Who this might be right for
Healthy
Wyeth is now a wholly owned subsidiary of Pfizer 14
Early research (Phase 1)Study completedNCT00692510
What this trial is testing

Drug Interaction Study Between AZD3480 and Cytochrome P450

Who this might be right for
MetabolismAlzheimer's Disease
AstraZeneca 18
Not applicableUnknownNCT00162877
What this trial is testing

The Role of CYP2C19 on the Eradication of H. Pylori Infection:Implication of PK/PD Relationships

Who this might be right for
Peptic Ulcer With H. Pylori InfectionGastritis With H. Pylori Infection
National Taiwan University Hospital 80
Not applicableStudy completedNCT03054220
What this trial is testing

Impact of Genetic Polymorphism on Drug-Drug Interactions Involving CYP2D6

Who this might be right for
Healthy
Jules Desmeules 34
Not applicableStudy completedNCT03154359
What this trial is testing

Atomoxetine PBPK-PD Clinical Study

Who this might be right for
ADHD
Children's Mercy Hospital Kansas City 51
Early research (Phase 1)Study completedNCT00651638
What this trial is testing

ARQ 197 in Healthy Volunteers to Assess the Pharmacokinetic (PK) Profile in Extensive and Poor Metabolizers as Defined by Cytochrome P450 2C19 (CYP 2C19) Genotype

Who this might be right for
Healthy
ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA) 17
Early research (Phase 1)Study completedNCT03072056
What this trial is testing

A Pharmacokinetic Study of MIN-101 and Its Metabolites in Healthy Subjects to Compare MIN-101 in Poor and Extensive Metabolizers

Who this might be right for
Healthy Subjects
Minerva Neurosciences 23

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