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Results for “Extensive Stage Small Cell Lung Cancer (ES-SCLC)”

148 trials

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Showing 20 of 148 results

Large-scale testing (Phase 3)Looking for participantsNCT06646276
What this trial is testing

Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).

Who this might be right for
Extensive-Stage Small Cell Lung Cancer
Bristol-Myers Squibb 530
Large-scale testing (Phase 3)Study completedNCT04063163
What this trial is testing

A Phase III Study to Investigate Efficacy and Safety of HLX10 + Chemotherapy in Patients With ES-SCLC

Who this might be right for
Extensive Stage Small Cell Lung Cancer
Shanghai Henlius Biotech 585
Large-scale testing (Phase 3)UnknownNCT03711305
What this trial is testing

Study of Carboplatin Plus Etoposide With or Without SHR-1316 in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC)

Who this might be right for
Extensive-stage Small Cell Lung Cancer
Jiangsu HengRui Medicine Co., Ltd. 462
Testing effectiveness (Phase 2)UnknownNCT04562337
What this trial is testing

SHR-1316 Combined With Chemotherapy and Chest Radiotherapy in ES-SCLC

Who this might be right for
Extensive-stage Small Cell Lung Cancer
Shandong Cancer Hospital and Institute 67
Early research (Phase 1)Active Not RecruitingNCT05787587
What this trial is testing

PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced or Metastatic Solid TumorsBreast CancerOvarian Cancer+6 more
IDEAYA Biosciences 216
Testing effectiveness (Phase 2)UnknownNCT04698941
What this trial is testing

Combined Simvastatin and Albumin Paclitaxel in Treating ES-SCLC Patients Relapsed From 1st Chemotherapy

Who this might be right for
Small Cell Lung Cancer
Shanghai Pulmonary Hospital, Shanghai, China 40
Early research (Phase 1)Active Not RecruitingNCT06898957
What this trial is testing

Study of Tarlatamab in Combination With YL201 With or Without Anti-programmed Death Ligand 1 (PD-L1) in Participants With Extensive Stage (ES) Small Cell Lung Cancer (SCLC)

Who this might be right for
Small Cell Lung Cancer
Amgen 29
Testing effectiveness (Phase 2)UnknownNCT04659785
What this trial is testing

Fluzoparib Combined With Apatinib as Second-Line Treatment of Patients With Extensive Stage Small Cell Lung Cancer（FA-ES-SCLC）

Who this might be right for
Small Cell Lung Cancer Extensive Stage
Tianjin Medical University Second Hospital 53
Early research (Phase 1)UnknownNCT06187740
What this trial is testing

Thoracic Consolidation Radiotherapy for ES-SCLC Treated With Chemo-immunotherapy

Who this might be right for
Small Cell Lung Cancer Extensive Stage
Fudan University 28
Testing effectiveness (Phase 2)Looking for participantsNCT06769126
What this trial is testing

Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

Who this might be right for
Extensive Stage Lung Small Cell CarcinomaLung Small Cell Carcinoma, A SubtypeLung Small Cell Carcinoma, I Subtype+2 more
SWOG Cancer Research Network 900
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06554535
What this trial is testing

Efficacy and Safety of Serplulimab With Chemotherapy and Aspirin in Untreated Extensive-Stage Small Cell Lung Cancer

Who this might be right for
Extensive-Stage Small Cell Lung CancerTreatment-naïve for Systemic Therapy Targeting Extensive-Stage Small Cell Lung CancerECOG Performance Status Score of 0 or 1+1 more
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Testing effectiveness (Phase 2)Looking for participantsNCT06536868
What this trial is testing

Tislelizumab Combined With Chemotherapy and Thoracic Radiotherapy in ES-SCLC

Who this might be right for
Extensive-stage Small-cell Lung Cancer
Second Hospital of Shanxi Medical University 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07501169
What this trial is testing

Sacituzumab Tirumotecan in Combination With Anlotinib in Previously Treated Patients With Extensive-Stage Small Cell Lung Cancer (ES-SCLC)

Who this might be right for
Extensive-stage Small Cell Lung Cancer (ES-SCLC)
Sichuan University 33
Large-scale testing (Phase 3)Active Not RecruitingNCT05091567
What this trial is testing

A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancer

Who this might be right for
Small-Cell Lung Cancer
Hoffmann-La Roche 660
Testing effectiveness (Phase 2)Looking for participantsNCT07564401
What this trial is testing

Evaluate DJI136, a DLL3-targeted CAR-T Therapy

Who this might be right for
Extensive-stage Small Cell Lung Cancer (ES-SCLC)
Novartis Pharmaceuticals 80
Testing effectiveness (Phase 2)Looking for participantsNCT06110572
What this trial is testing

Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation

Who this might be right for
Extensive Stage Lung Small Cell CarcinomaStage IV Lung Cancer
Vanderbilt-Ingram Cancer Center 18
Testing effectiveness (Phase 2)Looking for participantsNCT06663098
What this trial is testing

Atezolizumab and Rechallenge Chemotherapy in Relapsed Patients With Extensive-stage Small Cell Lung Cancer (ES-SCLC).

Who this might be right for
Extensive Stage Small Cell Lung Cancer (ES-SCLC)
Gruppo Oncologico Italiano di Ricerca Clinica 142
Testing effectiveness (Phase 2)Looking for participantsNCT05623319
What this trial is testing

Pembrolizumab and Olaparib Treatment of Extensive Small Cell Lung Cancer (ES-SCLC)

Who this might be right for
SCLC,Extensive Stage
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS 60
Large-scale testing (Phase 3)Active Not RecruitingNCT07005128
What this trial is testing

A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC)

Who this might be right for
Small-cell Lung CancerExtensive Stage Small-cell Lung Cancer
Amgen 350
Large-scale testing (Phase 3)UnknownNCT04535739
What this trial is testing

PCI for Patients With ES-SCLC After RCT:a Prospective Randomized Study

Who this might be right for
Small-cell Lung Cancer
Chinese Academy of Medical Sciences 414
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