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Results for “Extensive Stage Small Cell Lung Cancer (ES-SCLC)”

148 trials

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Showing 20 of 148 results

Testing effectiveness (Phase 2)Looking for participantsNCT06217757
What this trial is testing

Safety and Tolerability of LDRT+Sugemalimab+Chemotherapy+Olaparib for First-Line Treatment of SLFN-11 Positive ES-SCLC

Who this might be right for
Lung CancerExtensive-stage Small-cell Lung Cancer
Sichuan University 45
Not applicableActive Not RecruitingNCT06008353
What this trial is testing

A Real-World Assessment of the Demographic, Clinical Characteristics and Outcomes of a Brazilian Cohort of Previously Untreated Extensive Stage-Small Cell Lung Cancer Receiving Durvalumab Combined With Platinum-Etoposide in (ES-SCLC) in Brazil

Who this might be right for
Extensive-stage Small-cell Lung Cancer
AstraZeneca 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT05844150
What this trial is testing

PM8002 (Anti-PD-L1/VEGF) in Combination With Chemotherapy in Patients With ES-SCLC

Who this might be right for
SCLC
Biotheus Inc. 50
Not applicableNot Yet RecruitingNCT06982287
What this trial is testing

A Retrospective Real-World Study on the Efficacy and Safety of Anlotinib Hydrochloride Combined With Immunotherapy Maintenance Therapy Following Standard Chemoimmunotherapy for ES-SCLC (ALTER-L059)

Who this might be right for
Small Cell Lung Cancer Extensive Stage
Yong Fang 100
Testing effectiveness (Phase 2)UnknownNCT04985201
What this trial is testing

Combined Simvastatin and Irinotecan in Treating ES-SCLC Patients Relapsed From 1st Chemotherapy

Who this might be right for
Small Cell Lung Cancer
Shanghai Pulmonary Hospital, Shanghai, China 40
Testing effectiveness (Phase 2)UnknownNCT05245994
What this trial is testing

An Open Label, Multicenter Phase 2 Study of Durvalumab (MEDI4736) + Olaparib as Maintenance Therapy in Chinese

Who this might be right for
Lung CancerSmall Cell Lung CancerDurvalumab
Li Zhang, MD 60
Large-scale testing (Phase 3)Looking for participantsNCT06712355
What this trial is testing

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

Who this might be right for
Extensive-stage Small-cell Lung Cancer
BioNTech SE 621
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07289048
What this trial is testing

A Prospective, Single-Arm, Exploratory Study of IBI363 in ES-SCLC Patients After Immunotherapy Progression

Who this might be right for
SCLC,Extensive Stage
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 35
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07547332
What this trial is testing

Nab-Paclitaxel Combined With Local Therapy in Relapsed SCLC

Who this might be right for
Small Cell Lung CancerExtensive Stage Small Cell Lung Cancer (ES-SCLC)
Shanghai Pulmonary Hospital, Shanghai, China 84
Testing effectiveness (Phase 2)UnknownNCT05901584
What this trial is testing

Cadonilimab (AK104) With or Without CT as 2rd Line Treatment for ES-SCLC

Who this might be right for
ImmunotherapySecond-line Treatment
Second Affiliated Hospital of Zunyi Medical University 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT05092412
What this trial is testing

Low-dose Radiotherapy Combined With Durvalumab, Chemotherapy(EP) in the Treatment of ES-SCLC

Who this might be right for
Lung CancerExtensive-stage Small-cell Lung CancerDurvalumab
You Lu 30
Testing effectiveness (Phase 2)Looking for participantsNCT06110572
What this trial is testing

Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation

Who this might be right for
Extensive Stage Lung Small Cell CarcinomaStage IV Lung Cancer
Vanderbilt-Ingram Cancer Center 18
Testing effectiveness (Phase 2)UnknownNCT04562337
What this trial is testing

SHR-1316 Combined With Chemotherapy and Chest Radiotherapy in ES-SCLC

Who this might be right for
Extensive-stage Small Cell Lung Cancer
Shandong Cancer Hospital and Institute 67
Post-approval studies (Phase 4)Study completedNCT05071703
What this trial is testing

Evaluation of TRILACICLIB in Chinese Patients With Extensive-stage Small Cell Lung Cancer (ES-SCLC) for Chemotherapy-induced Myelosuppression, Antitumor Effects of Combination Regimens, and Safety in a Real-world Study

Who this might be right for
Extensive-stage Small-cell Lung Cancer
Jiangsu Simcere Pharmaceutical Co., Ltd. 30
Testing effectiveness (Phase 2)UnknownNCT05731518
What this trial is testing

SC0245 and Irinotecan in Treating Patients With Relapsed Extensive-Stage Small Cell Lung Cancer (ES-SCLC)

Who this might be right for
Small Cell Lung Cancer
Biocity Biopharmaceutics Co., Ltd. 67
Early research (Phase 1)Looking for participantsNCT07113691
What this trial is testing

Iadademstat + SBRT With Atezo in ES-SCLC

Who this might be right for
Extensive Stage Small Cell Lung Cancer (ES-SCLC)
Yale University 15
Early research (Phase 1)Ended earlyNCT03963414
What this trial is testing

Durvalumab Plus Tremelimumab With Chemotherapy in Untreated ES-SCLC

Who this might be right for
Small Cell Lung Carcinoma
University of Nebraska 1
Early research (Phase 1)Active Not RecruitingNCT05787587
What this trial is testing

PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced or Metastatic Solid TumorsBreast CancerOvarian Cancer+6 more
IDEAYA Biosciences 216
Early research (Phase 1)Looking for participantsNCT07413042
What this trial is testing

A Phase I Study to Evaluate the Safety and Preliminary Efficacy of [225Ac]Ac-DOTATATE Injection Combined With Tislelizumab in the Maintenance Treatment Period for Patients of Extensive-stage Small Cell Lung Cancer (ES-SCLC) With Somatostatin Receptors (SSTR)+ as First-line Treatment

Who this might be right for
SCLC, Extensive Stage
Peking University Cancer Hospital & Institute 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT05142696
What this trial is testing

[177Lu]Lu-DOTA-TATE in Newly Diagnosed ES-SCLC Patients in Combination With Carboplatin, Etoposide and Atezolizumab

Who this might be right for
Extensive Stage Small Cell Lung Cancer
Novartis Pharmaceuticals 55
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