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Results for “Extrapulmonary Neuroendocrine Neoplasms”

25 trials

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Showing 20 of 25 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07077564
What this trial is testing

The Efficacy of TROP2-ADC in Advanced Extrapulmonary High-Grade Neuroendocrine Neoplasms Failure of Standard Therapy

Who this might be right for
Neuroendocrine Neoplasms (Tumours)
Second Affiliated Hospital, School of Medicine, Zhejiang University 35
Testing effectiveness (Phase 2)Temporarily pausedNCT05337735
What this trial is testing

A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers

Who this might be right for
Microsatellite High CancersPeritoneal MesotheliomaExtrapulmonary High Grade+5 more
M.D. Anderson Cancer Center 140
Testing effectiveness (Phase 2)Active Not RecruitingNCT03896503
What this trial is testing

Randomized Trial of Topotecan With M6620, an ATR Kinase Inhibitor, in Small Cell Lung Cancers and Small Cell Cancers Outside of the Lungs

Who this might be right for
Extensive Stage Lung Small Cell CarcinomaExtrapulmonary Small Cell Neuroendocrine CarcinomaLimited Stage Lung Small Cell Carcinoma+3 more
National Cancer Institute (NCI) 104
Early research (Phase 1)Not Yet RecruitingNCT07488923
What this trial is testing

A First-in-human (FIH), Phase 1 Study of ML261, an Autologous Potency Enhanced Anti-DLL3 CAR T Cell Therapy, in Participants With R/R SCLC or Select NECs (SPECTRAL-1)

Who this might be right for
Small Cell Lung Cancer (SCLC )Extrapulmonary Neuroendocrine Carcinoma (EP-NEC)Gastroenteropancreatic NEC (GEP NEC)+1 more
Moonlight Bio, Inc 110
Not applicableNot Yet RecruitingNCT06924645
What this trial is testing

Fecal Microbiota Transplantation for Preventing Gastrointestinal Symptoms in Extrapulmonary Neuroendocrine Neoplasms: A Real-World Study

Who this might be right for
Treatment-related Gastrointestinal Toxicity (Including Diarrhea, Constipation, Nausea, and Vomiting)Extrapulmonary Neuroendocrine Neoplasms
Second Affiliated Hospital, School of Medicine, Zhejiang University 40
Testing effectiveness (Phase 2)Study completedNCT04705519
What this trial is testing

Nab-paclitaxel Combined with Bevacizumab in the Treatment of Metastatic Extrapulmonary Neuroendocrine Carcinoma

Who this might be right for
Neuroendocrine Carcinoma
Peking University 79
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06816394
What this trial is testing

Tarlatamab for Advanced Extrapulmonary Small Cell Carcinoma and Neuroendocrine Carcinoma (TAURUS)

Who this might be right for
Extrapulmonary Small Cell Carcinoma and Neuroendocrine Carcinoma
National Taiwan University Hospital 32
Testing effectiveness (Phase 2)WithdrawnNCT07328490
What this trial is testing

Bispecific T-Cell Engager Tarlatamab and TROP2 Targeted Antibody Drug Conjugate Sacituzumab Govitecan in Previously Treated Extensive-Stage Small Cell Lung Cancer and Extrapulmonary Neuroendocrine Cancer

Who this might be right for
Extensive-Stage Small Cell Lung CancerExtrapulmonary Neuroendocrine CarcinomaSmall Cell Carcinoma
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)UnknownNCT05076786
What this trial is testing

Chidamide Plus Etoposide and Cisplatin/Carboplatin as First-line Treatment for Extrapulmonary Neuroendocrine Carcinoma

Who this might be right for
Neuroendocrine TumorsNeuroendocrine Carcinoma
Peking Union Medical College Hospital 28
Testing effectiveness (Phase 2)UnknownNCT02695459
What this trial is testing

Cisplatinum and Everolimus in Patients With Metastatic or Unresectable NEC of Extrapulmonary Origin

Who this might be right for
Neuroendocrine Carcinomas
The Netherlands Cancer Institute 39
Early research (Phase 1)Not Yet RecruitingNCT07509034
What this trial is testing

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease

Who this might be right for
Extensive-Stage Small Cell Lung CancerExtrapulmonary Neuroendocrine CarcinomaRecurrent or Refractory+1 more
National Cancer Institute (NCI) 40
Testing effectiveness (Phase 2)Ended earlyNCT05420636
What this trial is testing

Iadademstat in Combination With Paclitaxel in Relapsed/Refractory SCLC and Extrapulmonary High Grade NET

Who this might be right for
Small-cell Lung CancerNeuroendocrine Carcinoma
Fox Chase Cancer Center 20
Testing effectiveness (Phase 2)Looking for participantsNCT07077551
What this trial is testing

NALIRIFOX as Second-Line Chemotherapy in Extrapulmonary High-grade Neuroendocrine Neoplasms: a Prospective, Single-center, Single-arm Trial

Who this might be right for
NENS
Second Affiliated Hospital, School of Medicine, Zhejiang University 28
Not applicableLooking for participantsNCT02146170
What this trial is testing

Tissue Procurement and Natural History Study of People With Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors

Who this might be right for
Non-Small Cell Lung CancerSmall Cell Lung CancerExtrapulmonary Small Cell Cancer+2 more
National Cancer Institute (NCI) 2,000
Testing effectiveness (Phase 2)Ended earlyNCT04042714
What this trial is testing

TAS-102 in Extrapulmonary Neuroendocrine Carcinoma

Who this might be right for
High-grade Extra Pulmonary Neuroendocrine Cancer
Baylor Research Institute 14
Testing effectiveness (Phase 2)Study completedNCT04010357
What this trial is testing

Targeted Therapy With CDK4/6 Inhibitors in Chemo-Refractory, Rb Wild-Type Extensive SCLC

Who this might be right for
Small-cell Lung CancerLarge Cell Neuroendocrine Carcinoma of the LungExtrapulmonary Small Cell Carcinoma
Case Comprehensive Cancer Center 14
Testing effectiveness (Phase 2)Looking for participantsNCT06503146
What this trial is testing

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

Who this might be right for
SarcomaSmall Cell Lung Cancer or Extrapulmonary Neuroendocrine Cancer (EP-NEC)Mesothelioma+7 more
National Cancer Institute (NCI) 320
Large-scale testing (Phase 3)Not Yet RecruitingNCT07544654
What this trial is testing

DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy

Who this might be right for
Extrapulmonary Neuroendocrine Cancer
Boehringer Ingelheim 390
Early research (Phase 1)Looking for participantsNCT07080242
What this trial is testing

Evaluating BL-M14D1 in Subjects With Locally Advanced or Metastatic Small Cell Lung Cancer and Neuroendocrine Tumors

Who this might be right for
Small Cell Lung Cancer Metastatic or Locally AdvancedNeuroendocrine CancerMetastatic Neuroendocrine Prostate Cancer+8 more
SystImmune Inc. 120
Early research (Phase 1)Active Not RecruitingNCT05262556
What this trial is testing

NP-101 (TQ Formula) With Nivolumab and Ipilimumab in Advanced or Metastatic Extra-pulmonary Neuroendocrine Carcinomas

Who this might be right for
Gastroenteropancreatic Neuroendocrine TumorGastroenteropancreatic Neuroendocrine NeoplasmNeuroendocrine Carcinoma+1 more
Amr Mohamed MD 15
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