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Results for “FTD-GRN”

13 trials

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Showing 13 of 13 results

Early research (Phase 1)Study completedNCT03636204
What this trial is testing

A First in Human Study in Healthy Volunteers and in Participants With Frontotemporal Dementia With Granulin (GRN) Mutation

Who this might be right for
HealthyFrontotemporal Dementia
Alector Inc. 64
Not applicableActive Not RecruitingNCT04516499
What this trial is testing

Neurofilament Surveillance Project (NSP)

Who this might be right for
Frontotemporal DementiaFrontotemporal Lobar DegenerationFTD-GRN+2 more
The Bluefield Project to Cure Frontotemporal Dementia 342
Testing effectiveness (Phase 2)Active Not RecruitingNCT05262023
What this trial is testing

Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia (FTD-GRN)

Who this might be right for
Frontotemporal Dementia
Denali Therapeutics Inc. 85
Not applicableWithdrawnNCT06711510
What this trial is testing

Predict to Prevent PGRN Disease

Who this might be right for
Frontotemporal Dementia (FTD)GRN Related Frontotemporal Dementia
Assistance Publique - Hôpitaux de Paris
Testing effectiveness (Phase 2)Looking for participantsNCT06064890
What this trial is testing

Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)

Who this might be right for
Frontotemporal DementiaFTDFTD-GRN+1 more
AviadoBio Ltd 9
Early research (Phase 1)Study completedNCT06226064
What this trial is testing

Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VES001 in Healthy Participants

Who this might be right for
Dementia, Frontotemporal
Vesper Biotechnologies ApS 78
Large-scale testing (Phase 3)Ended earlyNCT04374136
What this trial is testing

Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

Who this might be right for
Frontotemporal Dementia
Alector Inc. 119
Early research (Phase 1)Study completedNCT06705192
What this trial is testing

Study in Asymptomatic GRN-FTD Patients to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VES001

Who this might be right for
DementiaFrontotemporal DementiaAsymptomatic Condition
Mads Kjolby 6
Not applicableLooking for participantsNCT04363684
What this trial is testing

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

Who this might be right for
Frontotemporal Lobar Degeneration (FTLD)Progressive Supranuclear Palsy (PSP)Corticobasal Degeneration (CBD)+11 more
Mayo Clinic 2,100
Testing effectiveness (Phase 2)Looking for participantsNCT04747431
What this trial is testing

PBFT02 in Participants With FTD and Mutations in the Granulin Precursor (GRN) or C9ORF72 Genes

Who this might be right for
Frontotemporal DementiaFTDFTD-GRN+2 more
Passage Bio, Inc. 30
Not applicableStudy completedNCT02999282
What this trial is testing

Rehabilitative Trial for the Rescue of Neurophysiological Parameters in Progranulin Deficient Subjects

Who this might be right for
Frontotemporal DementiaGRN Related Frontotemporal Dementia
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia 70
Testing effectiveness (Phase 2)Active Not RecruitingNCT04408625
What this trial is testing

Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)

Who this might be right for
Frontotemporal Dementia
Prevail Therapeutics 35
Not applicableStudy completedNCT04060082
What this trial is testing

Voices Of Individuals: Challenges and Experiences Of bvFTD

Who this might be right for
Frontotemporal DementiaFrontotemporal DegenerationFrontotemporal Dementia, Behavioral Variant+1 more
University of Pennsylvania 26