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Results for “FXI”

Showing 17 of 0 results

Not applicableUnknownNCT02785718
What this trial is testing

The Proteins of the Contact Activation System

Who this might be right for
Factor XI DeficiencyFactor XII Deficiency
Hospices Civils de Lyon 18
Large-scale testing (Phase 3)Ended earlyNCT05171075
What this trial is testing

A Study Comparing Abelacimab to Dalteparin in the Treatment of Gastrointestinal/Genitourinary Cancer and Associated VTE

Who this might be right for
Venous ThromboembolismDeep Venous ThrombosisPulmonary Embolism
Anthos Therapeutics, Inc. 417
Testing effectiveness (Phase 2)Active Not RecruitingNCT06180889
What this trial is testing

Factor XI inhibiTion for the Prevention of Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty

Who this might be right for
Knee Arthroplasty, Total
Suzhou Alphamab Co., Ltd. 241
Testing effectiveness (Phase 2)Study completedNCT06454630
What this trial is testing

A Trial to Learn How Well REGN7508 Works for Preventing Blood Clots After a Knee Replacement in Adult Participants

Who this might be right for
Venous Thromboembolism
Regeneron Pharmaceuticals 179
Not applicableStudy completedNCT00890812
What this trial is testing

Factor XI Levels in Acute Ischemic Stroke

Who this might be right for
Stroke
University of Utah 450
Large-scale testing (Phase 3)Not Yet RecruitingNCT07697599
What this trial is testing

Venous Thromboembolism (VTE) Prophylaxis With REGN7508 and REGN9933 in Adult and Adolescent Participants With a Peripherally Inserted Central Catheter (PICC)

Who this might be right for
Venous Thromboembolism (VTE)
Regeneron Pharmaceuticals 1,908
Large-scale testing (Phase 3)Looking for participantsNCT07015905
What this trial is testing

REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults

Who this might be right for
Venous Thromboembolism (VTE)
Regeneron Pharmaceuticals 2,000
Testing effectiveness (Phase 2)Study completedNCT04534114
What this trial is testing

Factor XI LICA to Reduce Events Such as Heart Attack and Stroke in Patients Whose Kidneys Are no Longer Able to Work as They Should and Require Treatment to Filter Wastes From the Blood: Focus is on the Safety of BAY2976217 and the Way the Body Absorbs, Distributes and Removes the Study Drug

Who this might be right for
End Stage Renal Disease Requiring Hemodialysis
Bayer 307
Large-scale testing (Phase 3)Looking for participantsNCT07318610
What this trial is testing

Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With Peripheral Artery Disease

Who this might be right for
Peripheral Artery Disease (PAD)
Regeneron Pharmaceuticals 7,050
Large-scale testing (Phase 3)Looking for participantsNCT07410117
What this trial is testing

REGN7508 in Adult Participants for Prevention of Cancer-Associated Thrombosis

Who this might be right for
Cancer-Associated Thrombosis (CAT)
Regeneron Pharmaceuticals 1,120
Testing effectiveness (Phase 2)Study completedNCT05618808
What this trial is testing

A Trial to Learn How Well REGN9933 Works for Preventing Blood Clots After Knee Replacement Surgery in Adult Participants

Who this might be right for
Venous Thromboembolism
Regeneron Pharmaceuticals 373
Testing effectiveness (Phase 2)Study completedNCT03358030
What this trial is testing

ISIS 416858 Administered Subcutaneously to Participants With End-Stage Renal Disease (ESRD) on Hemodialysis

Who this might be right for
End-stage Renal Disease (ESRD)
Ionis Pharmaceuticals, Inc. 213
Not applicableUnknownNCT01114074
What this trial is testing

Thrombus Formation Under Different Flow-conditions

Who this might be right for
Thrombosis
Maastricht University Medical Center 46
Large-scale testing (Phase 3)Looking for participantsNCT07493304
What this trial is testing

Treatment and Secondary Prevention of Venous Thromboembolism (VTE) in Adult Participants With Solid and Hematologic Cancers

Who this might be right for
Venous Thromboembolism (VTE)
Regeneron Pharmaceuticals 1,600
Early research (Phase 1)Active Not RecruitingNCT05844293
What this trial is testing

Single Ascending Dose of FXI-GalNAc-siRNA in Healthy Subjects

Who this might be right for
FXI
Sirnaomics 40
Early research (Phase 1)Study completedNCT03582462
What this trial is testing

Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of IONIS FXI-LRx in up to 84 Healthy Volunteers

Who this might be right for
Healthy Participants
Ionis Pharmaceuticals, Inc. 66
Early research (Phase 1)Study completedNCT05603195
What this trial is testing

A Trial to Learn if Single Ascending Intravenous (IV) Doses of REGN7508 Are Safe and Well Tolerated, and How it Works in the Body of Healthy Adult Participants

Who this might be right for
Healthy Volunteer
Regeneron Pharmaceuticals 80

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