Not applicableUnknownNCT05911698What this trial is testingFractional co2 Laser Followed by Either Vitamin c or Tranexamic Acid in Treatment of Melasma.Who this might be right forMelasma Khadija Qenawi 25
Not applicableUnknownNCT06516224What this trial is testingAnti-pigmenting Effect of a Routine of Facial Products in Subjects With MelasmaWho this might be right forMelasma Cosmetique Active International 150
Not applicableStudy completedNCT03565341What this trial is testingEfficacy and Safety of PiQo4 Device for Treatment of MelasmaWho this might be right forMelasma Focus Medical, LLC 20
Testing effectiveness (Phase 2)Enrolling By InvitationNCT07169383What this trial is testingOral Melatonin Versus Oral Tranexamic Acid in the Management of MelasmaWho this might be right forMelasma (Facial Melasma) Hina Malik 160
Testing effectiveness (Phase 2)WithdrawnNCT06473974What this trial is testingOpen-label, Single-arm, Proof of Concept Study in Subjects with Mild-to-moderate Facial HyperpigmentationWho this might be right forFacial Hyperpigmentation Kayuraeffect, LLP
Not applicableUnknownNCT06320314What this trial is testingEfficacy and Tolerability of Tested Formula After 3 Months in Treatment of Facial Hyperpigmentation of 3 OriginsWho this might be right forHyperpigmentation Cosmetique Active International 60
Not applicableStudy completedNCT03040089What this trial is testingEfficacy and Safety of Picosecond, Neodymium-doped Yttrium Aluminum Garnet Laser Therapy Using 1,064 nm and 595 nmWho this might be right forMelasma CynosureLutronic 40
Post-approval studies (Phase 4)Enrolling By InvitationNCT07696806What this trial is testingMicroneedling-Assisted Metformin, Tranexamic Acid, and Modified Kligman's Formula for MelasmaWho this might be right forMelasma (Facial Melasma) Sameh Sarsik 80
Not applicableStudy completedNCT00467233What this trial is testingStudy of Acid Peel and Laser for the Treatment of MelasmaWho this might be right forMelasma Northwestern University 15
Not applicableNot Yet RecruitingNCT07060157What this trial is testingComparative Efficacy of Resveratrol 1 % Gel and Trichloroacetic Acid 20% in Treatment of Melasma: A Split-face StudyWho this might be right forMelasma Assiut University 41
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07779811What this trial is testingTopical Metformin Versus Triple Regimen for Epidermal MelasmaWho this might be right forEpidermal MelasmaFacial Hyperpigmentation Combined Military Hospital, Pakistan 104
Not applicableNot Yet RecruitingNCT07485777What this trial is testingComparative Evaluation of Topical 30% Metformin and Kligman's Regimen in Women With MelasmaWho this might be right forMelasma (Facial Melasma)Melasma Foundation University Islamabad 82
Not applicableNot Yet RecruitingNCT06763367What this trial is testingClinical Evaluation and Study of the Efficacy of a Centella Asiatica-Infused Facial Mask on Discosmetic DermatosisWho this might be right forRosaceaAcneCentella+1 more Nanjing First Hospital, Nanjing Medical University 30
Not applicableUnknownNCT03008655What this trial is testing1064-nm Q-switched Nd:YAG Laser and Intradermal Tranexamic Acid for MelasmaWho this might be right forMelasma Taipei Medical University WanFang Hospital 20
Not applicableLooking for participantsNCT07679945What this trial is testingA Clinical Study to Evaluate the Efficacy in Improving Dark Spots After 8 Weeks of Use of Facial Sunscreens in Adult ParticipantsWho this might be right forPost-inflammatory HyperpigmentationMelasmaSolar Lentigo Kenvue Brands LLC 152
Post-approval studies (Phase 4)UnknownNCT03686787What this trial is testingOral Tranexamic Acid and Laser for Treatment of MelasmaWho this might be right forMelasma Laser and Skin Surgery Center of New York 32
Not applicableLooking for participantsNCT07769268What this trial is testingEfficacy Evaluation of a Cosmetic Product for Facial HyperpigmentationWho this might be right forHyperpigmentationMelasma (Facial Melasma) Brainfarma Industria Química e Farmacêutica S/A 40
Not applicableUnknownNCT05656833What this trial is testingCombination Topical Cysteamine and Fractional 1927nm Low-Powered Diode Laser for Treatment of Facial MelasmaWho this might be right forMelasma UnionDerm 20
Not applicableStudy completedNCT05710068What this trial is testingEffects of RF Microneedle on Photoaging SkinWho this might be right forPigmentationPigmentation Disorder Ajou University School of Medicine 15
Large-scale testing (Phase 3)Study completedNCT04170088What this trial is testingComparison of Efficacy of Tranexamic Acid Mesotherapy Versus 0.9% Normal Saline for MelasmaWho this might be right forEffect of DrugsAdverse Effects of Medical Drugs Jinnah Postgraduate Medical Centre 30