Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Factor XI”

28 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 28 results

Early research (Phase 1)Study completedNCT05603195
What this trial is testing

A Trial to Learn if Single Ascending Intravenous (IV) Doses of REGN7508 Are Safe and Well Tolerated, and How it Works in the Body of Healthy Adult Participants

Who this might be right for
Healthy Volunteer
Regeneron Pharmaceuticals 80
Not applicableUnknownNCT03347591
What this trial is testing

Rare Bleeding Disorders in the Netherlands

Who this might be right for
Rare Bleeding Disorders
Radboud University Medical Center 300
Testing effectiveness (Phase 2)Active Not RecruitingNCT06180889
What this trial is testing

Factor XI inhibiTion for the Prevention of Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty

Who this might be right for
Knee Arthroplasty, Total
Suzhou Alphamab Co., Ltd. 241
Testing effectiveness (Phase 2)Study completedNCT04534114
What this trial is testing

Factor XI LICA to Reduce Events Such as Heart Attack and Stroke in Patients Whose Kidneys Are no Longer Able to Work as They Should and Require Treatment to Filter Wastes From the Blood: Focus is on the Safety of BAY2976217 and the Way the Body Absorbs, Distributes and Removes the Study Drug

Who this might be right for
End Stage Renal Disease Requiring Hemodialysis
Bayer 307
Early research (Phase 1)Looking for participantsNCT07430397
What this trial is testing

A Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CITY-FXI in Healthy Adults and Adults With FV Leiden or Prothrombin G20210A Mutation

Who this might be right for
Factor V LeidenProthrombin G20210A
City Therapeutics 128
Large-scale testing (Phase 3)Not Yet RecruitingNCT07493304
What this trial is testing

Treatment and Secondary Prevention of Venous Thromboembolism (VTE) in Adult Participants With Solid and Hematologic Cancers

Who this might be right for
Venous Thromboembolism (VTE)
Regeneron Pharmaceuticals 1,600
Testing effectiveness (Phase 2)WithdrawnNCT03398434
What this trial is testing

Efficacy and Safety of MAA868 in Patients With Atrial Fibrillation

Who this might be right for
Atrial Fibrillation
Novartis Pharmaceuticals
Large-scale testing (Phase 3)Not Yet RecruitingNCT07318610
What this trial is testing

Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With Peripheral Artery Disease

Who this might be right for
Peripheral Artery Disease (PAD)
Regeneron Pharmaceuticals 7,050
Early research (Phase 1)Study completedNCT03582462
What this trial is testing

Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of IONIS FXI-LRx in up to 84 Healthy Volunteers

Who this might be right for
Healthy Participants
Ionis Pharmaceuticals, Inc. 66
Not applicableNo Longer AvailableNCT01701947
What this trial is testing

HEMOLEVEN® Expanded Access Program Prevention of Surgical/Postpartum Hemorrhage Severe Inherited Factor XI Deficiency

Who this might be right for
Wound; Rupture, Surgery, Cesarean SectionPostpartum HemorrhageSurgery
Laboratoire français de Fractionnement et de Biotechnologies
Early research (Phase 1)Study completedNCT02902679
What this trial is testing

Evaluate the Safety and Pharmacokinetics of BMS-986177 in Participants With End-stage Renal Dysfunction on Chronic Stable Hemodialysis Treatment

Who this might be right for
ThrombosisFactor XIRenal Impairment+1 more
Bristol-Myers Squibb 6
Testing effectiveness (Phase 2)UnknownNCT04833764
What this trial is testing

Mechanisms of Deep Vein Thrombosis (DVT) and Vein Wall Fibrosis

Who this might be right for
Post-thrombotic SyndromeDeep Vein Thrombosis Leg
Khanh Nguyen 30
Testing effectiveness (Phase 2)Study completedNCT03358030
What this trial is testing

ISIS 416858 Administered Subcutaneously to Participants With End-Stage Renal Disease (ESRD) on Hemodialysis

Who this might be right for
End-stage Renal Disease (ESRD)
Ionis Pharmaceuticals, Inc. 213
Testing effectiveness (Phase 2)Active Not RecruitingNCT04755283
What this trial is testing

Safety and Tolerability of Abelacimab (MAA868) vs. Rivaroxaban in Patients With Atrial Fibrillation

Who this might be right for
Atrial Fibrillation (AF)Stroke
Anthos Therapeutics, Inc. 1,287
Testing effectiveness (Phase 2)Study completedNCT05027074
What this trial is testing

Global Study of MK-2060 (Anti-Factor XI Monoclonal Antibody) in Participants With End Stage Renal Disease Receiving Hemodialysis (FXI Hemodialysis Study) (MK-2060-007)

Who this might be right for
End-Stage Renal DiseaseEnd-Stage Kidney DiseaseKidney Failure, Chronic
Merck Sharp & Dohme LLC 506
Early research (Phase 1)Study completedNCT05102136
What this trial is testing

Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of REGN9933 in Adult Healthy Volunteers

Who this might be right for
Healthy Volunteers
Regeneron Pharmaceuticals 56
Large-scale testing (Phase 3)Looking for participantsNCT07213778
What this trial is testing

REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants

Who this might be right for
Symptomatic Venous Thromboembolism (VTE)
Regeneron Pharmaceuticals 2,000
Early research (Phase 1)Study completedNCT06444178
What this trial is testing

Assessment of Gastrointestinal Blood Loss After Receiving Aspirin or Aspirin Plus Rivaroxaban, or Aspirin Plus REGN9933, or Aspirin Plus REGN7508 in Healthy Adult Participants

Who this might be right for
Healthy Volunteers
Regeneron Pharmaceuticals 224
Large-scale testing (Phase 3)Not Yet RecruitingNCT07430956
What this trial is testing

Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable

Who this might be right for
Atrial Fibrillation (AF)
Regeneron Pharmaceuticals 2,628
Not applicableUnknownNCT01114074
What this trial is testing

Thrombus Formation Under Different Flow-conditions

Who this might be right for
Thrombosis
Maastricht University Medical Center 46
Load More Results