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Results for “Familial Alzheimer Disease (FAD)”

11 trials

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Showing 11 of 11 results

Testing effectiveness (Phase 2)Study completedNCT01998841
What this trial is testing

Crenezumab Versus Placebo in Preclinical Presenilin1 (PSEN1) E280A Mutation Carriers to Evaluate Efficacy and Safety in the Treatment of Autosomal-Dominant Alzheimer's Disease (AD), Including a Placebo-Treated Non-Carrier Cohort

Who this might be right for
Alzheimer's Disease
Genentech, Inc. 252
Testing effectiveness (Phase 2)Study completedNCT04413344
What this trial is testing

Repurposing Bromocriptine for Abeta Metabolism in Alzheimer's Disease

Who this might be right for
Familial Alzheimer Disease (FAD)PSEN1 Mutation
Kyoto University 8
Not applicableLooking for participantsNCT03657732
What this trial is testing

The Chinese Familial Alzheimer's Network

Who this might be right for
Alzheimer DiseaseFamilial Alzheimer Disease (FAD)
Capital Medical University 40,000
Large-scale testing (Phase 3)Not Yet RecruitingNCT06996730
What this trial is testing

Donanemab, RG6289, or the Combination of Donanemab and RG6289 in Presenilin 1 (PSEN1) E280A Mutation Carriers for the Treatment of Autosomal-Dominant Alzheimer's Disease

Who this might be right for
Autosomal Dominant Alzheimers DiseaseEarly Onset Alzheimer DiseaseAlzheimers Disease
Banner Health 240
Not applicableActive Not RecruitingNCT05637801
What this trial is testing

A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (Hope Study, CA-0011)

Who this might be right for
Alzheimer DiseaseAlzheimer Disease 1Alzheimer Disease 2+32 more
Cognito Therapeutics, Inc. 670
Not applicableLooking for participantsNCT03653156
What this trial is testing

China Cognition and Aging Study

Who this might be right for
Mild Cognitive Impairment(MCI)Alzheimer Disease, Late OnsetFamilial Alzheimer Disease (FAD)+3 more
Capital Medical University 100,000
Testing effectiveness (Phase 2)Study completedNCT03977584
What this trial is testing

Tau Positron Emission Tomography (PET) Longitudinal Substudy Associated With: Study of Crenezumab Versus Placebo in Preclinical Presenilin1 (PSEN1) E280A Mutation Carriers in the Treatment of Autosomal-Dominant Alzheimer's Disease

Who this might be right for
Alzheimer Disease
Hoffmann-La Roche 114
Post-approval studies (Phase 4)UnknownNCT05969054
What this trial is testing

Improvement Effect of Lacosamide and Levetiracetam on Cognitive in Alzheimer's Disease Patients With Epilepsy

Who this might be right for
Alzheimer Disease 3Epilepsy
Xiangya Hospital of Central South University 140
Testing effectiveness (Phase 2)UnknownNCT03806478
What this trial is testing

Study of APH-1105 in Patients With Mild to Moderate Alzheimer's Disease

Who this might be right for
DementiaAlzheimer Disease 1Alzheimer Disease 2+1 more
Aphios 60
Early research (Phase 1)Looking for participantsNCT06372821
What this trial is testing

A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK

Who this might be right for
Alzheimer DiseaseAutosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder)Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 2 (Disorder)+1 more
University College, London 10
Not applicableWithdrawnNCT04100889
What this trial is testing

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Alzheimer's Disease

Who this might be right for
Alzheimer DiseaseAlzheimer Disease 1Alzheimer Disease 2+20 more
ProgenaBiome