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Results for “Familial Amyloid Polyneuropathy (FAP)”

115 trials

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Showing 20 of 115 results

Large-scale testing (Phase 3)Study completedNCT03860935
What this trial is testing

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy

Who this might be right for
AmyloidosisAmyloid CardiomyopathyTransthyretin Amyloidosis+2 more
Eidos Therapeutics, a BridgeBio company 632
Large-scale testing (Phase 3)Looking for participantsNCT06672237
What this trial is testing

NTLA-2001 in ATTRv-PN

Who this might be right for
Neuromuscular DiseaseNeuromuscular Diseases (NMD)Neurodegenerative Disease+17 more
Intellia Therapeutics 60
Not applicableLooking for participantsNCT07213297
What this trial is testing

Comprehensive Program for Hereditary Transthyretin Amyloidosis

Who this might be right for
Amyloidosis in Transthyretin (TTR)Amyloidosis, Familial
Hospital de Alta Complejidad en Red 20
Not applicableLooking for participantsNCT05489549
What this trial is testing

Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

Who this might be right for
Amyloidosis, HereditaryAmyloidosis CardiacAmyloidosis, Familial+2 more
University of Texas Southwestern Medical Center 500
Not applicableUnknownNCT04986826
What this trial is testing

Exercise Effect on Transthyretin Stability

Who this might be right for
Amyloidosis TransthyretinAthlete Heart
Oregon Health and Science University 24
Not applicableLooking for participantsNCT07205666
What this trial is testing

The Eplontersen Pregnancy and Lactation Outcomes Study

Who this might be right for
Transthyretin Amyloidosis
AstraZeneca 10
Not applicableWithdrawnNCT02713880
What this trial is testing

Biomarker for Transthyretin-Related Familial Amyloidotic Polyneuropathy (BioTRAP)

Who this might be right for
Transthyretin AmyloidosisTransthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin Amyloid Cardiopathy
CENTOGENE GmbH Rostock
Not applicableStudy completedNCT04201418
What this trial is testing

Observational Study to Evaluate the Effectiveness of Patisiran in Patients With Polyneuropathy of ATTRv Amyloidosis With a V122I or T60A Mutation

Who this might be right for
Hereditary Transthyretin-mediated (ATTRv) AmyloidosisPolyneuropathy
Alnylam Pharmaceuticals 67
Testing effectiveness (Phase 2)Looking for participantsNCT06539208
What this trial is testing

A Phase I/IIa，Open-label, Single Ascending Dose and Dose-expansion Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of YOLT-201 in Patients With Transthyretin Amyloidosis Polyneuropathy (ATTR-PN) or Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin Amyloidosis PolyneuropathyTransthyrexin Amyloidosis Cardiomyopathy
YolTech Therapeutics Co., Ltd 31
Not applicableStudy completedNCT00628745
What this trial is testing

Transthyretin Amyloidosis Outcome Survey (THAOS)

Who this might be right for
Transthyretin Gene MutationsTransthyretin Amyloidosis
Pfizer 6,718
Not applicableStudy completedNCT01432587
What this trial is testing

The Effect of Diflunisal on Familial Transthyretin Amyloidosis

Who this might be right for
Amyloidosis
Umeå University 55
Large-scale testing (Phase 3)Study completedNCT01737398
What this trial is testing

Efficacy and Safety of Inotersen in Familial Amyloid Polyneuropathy

Who this might be right for
FAPFamilial Amyloid PolyneuropathyTTR+2 more
Ionis Pharmaceuticals, Inc. 173
Not applicableLooking for participantsNCT05929209
What this trial is testing

Exploring Biomarkers in Hereditary Transthyretin Amyloidosis

Who this might be right for
Hereditary Transthyretin Amyloidosis
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 80
Not applicableActive Not RecruitingNCT05873868
What this trial is testing

Myocardial Effects in Patients With ATTRv With Polyneuropathy Treated With Patisiran or Vutrisiran

Who this might be right for
Transthyretin AmyloidosisAmyloidosis, Hereditary
Rennes University Hospital 20
Large-scale testing (Phase 3)Enrolling By InvitationNCT06679946
What this trial is testing

Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Alnylam Pharmaceuticals 700
Testing effectiveness (Phase 2)Study completedNCT05635045
What this trial is testing

Evuzamitide in PET/CT to Measure Potential Therapeutic Response in ATTR

Who this might be right for
Transthyretin Amyloidosis
Columbia University 10
Not applicableUnknownNCT05814380
What this trial is testing

The Regional Scintigraphic DPD Uptake in Cardiac Transthyretin Amyloidosis.

Who this might be right for
Transthyretin Amyloidosis
Katarzyna Holcman 100
Not applicableStudy completedNCT05560555
What this trial is testing

Retrospective Study Collecting Neurological Follow-up of Hereditary Transthyretin Amyloidosis (ATTRv) Patients Included in B3461028 and B3461045.

Who this might be right for
Hereditary Transthyretin Amyloidosis (ATTRv)Polyneuropathy
Pfizer 5
Not applicableUnknownNCT05699044
What this trial is testing

Screening of ATTRwt in Patient With Advanced AV-Block Undergoing Pacemaker Implantation

Who this might be right for
Amyloid CardiomyopathyBlock, AV
Steen Hvitfeldt Poulsen 170
Very early researchStudy completedNCT03591757
What this trial is testing

Short-term Effects of TOLCAPONE on Transthyretin Stability in Subjects With Leptomeningeal TTR Amyloidosis (ATTR)

Who this might be right for
Transthyretin AmyloidosisAmyloidosis, Leptomeningeal, Transthyretin-Related
Boston University 10
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