Not applicableLooking for participantsNCT06217588What this trial is testingLCAT (Lecithin Cholesterol Acyl Transferase) Natural History StudyWho this might be right forLCAT Deficiency University of Pennsylvania 40
Not applicableWithdrawnNCT03756779What this trial is testingCross-over Pilot Study of Blood Cholesterol Response to Dietary Saturated Fat in Patients With Autosomal Dominant HypercholesterolemiaWho this might be right forFamilial Hypercholesterolemia University of Texas Southwestern Medical Center
Not applicableStudy completedNCT03018678What this trial is testingScreening Protocol for a Gene Therapy Trial in Subjects With Homozygous Familial HypercholesterolemiaWho this might be right forHypercholesterolemia, Familial University of Pennsylvania 21
Early research (Phase 1)Study completedNCT02709850What this trial is testingSafety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS ANGPTL3-LRx in Healthy Volunteers With Elevated Triglycerides and Participants With Familial HypercholesterolemiaWho this might be right forHypertriglyceridemiaFamilial Hypercholesterolemia Ionis Pharmaceuticals, Inc. 48
Not applicableStudy completedNCT02726100What this trial is testingSMARTHealth Diabetes in China Using Lay Family Health PromotersWho this might be right forDiabetes Mellitus, Type 2HypertensionDyslipidemias The George Institute for Global Health, China 2,073
Not applicableWithdrawnNCT00064688What this trial is testingGenomic Dissection of a QTL Affecting the Lipid ProfileWho this might be right forCardiovascular DiseasesHeart DiseasesObesity+1 more Medical College of Wisconsin
Early research (Phase 1)Looking for participantsNCT06451770What this trial is testingPhase 1b Study of VERVE-201 in Patients With Refractory HyperlipidemiaWho this might be right forHypercholesterolemiaHypertriglyceridemiaRefractory Hyperlipidemia Verve Therapeutics, Inc. 36
Not applicableNot Yet RecruitingNCT06675994What this trial is testingIn Vitro Demonstration of Direct Platelet-Related Effects of PCSK9 EnzymeWho this might be right forHealthyHypercholesterolemiaHypertension+6 more LifeBridge Health 80
Not applicableActive Not RecruitingNCT04656028What this trial is testingGenetic Testing and Motivational Counseling for FHWho this might be right forHypercholesterolemia, FamilialHypercholesterolemia, Familial, 1Hypercholesterolemia, Familial, 2+23 more National Medical Research Center for Therapy and Preventive Medicine 180
Not applicableStudy completedNCT00365235What this trial is testingUnderstanding the Genetic Basis of Familial Combined Hyperlipidemia in Mexican IndividualsWho this might be right forHyperlipidemia, Familial CombinedCoronary Disease University of California, Los Angeles 998
Not applicableLooking for participantsNCT05693701What this trial is testingMulticomponent Intervention Study- Blood Donors With High CholesterolWho this might be right forLipid Metabolism Disorder University of Texas Southwestern Medical Center 100
Not applicableLooking for participantsNCT04370899What this trial is testingEarly Detection of Familial Hypercholesterolemia in ChildrenWho this might be right forFamilial HypercholesterolemiaFamilial Hypercholesterolemia - HeterozygousFamilial Hypercholesterolemia - Homozygous Institut Investigacio Sanitaria Pere Virgili 400
Not applicableUnknownNCT05066932What this trial is testingAdvanced Lipoproptein Profiling and Cardiovascular Risk Stratification in Familial HypercholesterolemiaWho this might be right forFamilial HypercholesterolemiaAtherosclerosis Assistance Publique - Hôpitaux de Paris 100
Post-approval studies (Phase 4)Study completedNCT03403374What this trial is testingSafety and Tolerability of Repatha® (Evolocumab) in Indian Participants With Homozygous Familial HypercholesterolemiaWho this might be right forHomozygous Familial Hypercholesterolemia HoFH Amgen 30
Early research (Phase 1)Study completedNCT05851066What this trial is testingA VSA003 Phase 1 Study in Chinese Adult Healthy VolunteersWho this might be right forDyslipidemiasFamilial HypercholesterolemiaHypertriglyceridemia Visirna Therapeutics HK Limited 36
Large-scale testing (Phase 3)Study completedNCT00116870What this trial is testingMARS - Monitored Atherosclerosis Regression StudyWho this might be right forAtherosclerosisCoronary Artery Disease Merck Sharp & Dohme LLC 270
Large-scale testing (Phase 3)Study completedNCT00827606What this trial is testingAtorvastatin Three Year Pediatric StudyWho this might be right forFamilial Hypercholesterolemia Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 272
Large-scale testing (Phase 3)Study completedNCT03337308What this trial is testingA Study Evaluating the Safety and Efficacy of Bempedoic Acid Plus Ezetimibe Fixed-Dose Combination Compared to Bempedoic Acid, Ezetimibe, and Placebo in Patients Treated With Maximally Tolerated Statin TherapyWho this might be right forHyperlipidemias Esperion Therapeutics, Inc. 382
Not applicableStudy completedNCT00705211What this trial is testingA 52-week Post-marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05245)Who this might be right forHypercholesterolemiaFamilial HypercholesterolemiaHomozygous Sitosterolemia Organon and Co 1,794
Large-scale testing (Phase 3)Looking for participantsNCT07037771What this trial is testingZodasiran in Adolescent and Adult Subjects With Homozygous Familial Hypercholesterolemia (YOSEMITE)Who this might be right forHomozygous Familial Hypercholesterolemia Arrowhead Pharmaceuticals 60