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Results for “Familial Hypercholesterolemia With Hyperlipemia”

184 trials

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Showing 20 of 184 results

Early research (Phase 1)Study completedNCT05398029
What this trial is testing

VERVE-101 in Patients With Familial Hypercholesterolemia and Cardiovascular Disease

Who this might be right for
Heterozygous Familial HypercholesterolemiaAtherosclerotic Cardiovascular DiseaseHypercholesterolemia
Verve Therapeutics, Inc. 13
Not applicableStudy completedNCT04148001
What this trial is testing

Identifying and Genotyping Homozygous Familial Hypercholesterolemia (HoFH) Patients

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
REGENXBIO Inc. 4
Not applicableApproved For MarketingNCT06500598
What this trial is testing

Compassionate Use of Evinacumab

Who this might be right for
Pediatric Homozygous Familial Hypercholesterolemia (HoFH)Severe Hypertriglyceridemia (HTG)Dysbetalipoproteinemia (DBL)
Regeneron Pharmaceuticals
Not applicableStudy completedNCT00001204
What this trial is testing

Cardiovascular Evaluation of Patients With High Cholesterol and Normal Volunteers

Who this might be right for
Homozygous Familial Hypercholesterolemic
National Heart, Lung, and Blood Institute (NHLBI) 73
Large-scale testing (Phase 3)Not Yet RecruitingNCT07421284
What this trial is testing

Evaluate the Safety, Efficacy of SYH2053 in Chinese Participants With Non-familial Hypercholesterolemia and Mixed Hyperlipidemia on a Background of Lipid-lowering Therapy

Who this might be right for
Non-familial Hypercholesterolemia and Mixed Hyperlipidemia
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. 900
Large-scale testing (Phase 3)Looking for participantsNCT06597006
What this trial is testing

Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Novartis Pharmaceuticals 9
Large-scale testing (Phase 3)Study completedNCT03814187
What this trial is testing

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

Who this might be right for
ASCVDElevated CholesterolHeterozygous Familial Hypercholesterolemia+1 more
Novartis Pharmaceuticals 3,275
Early research (Phase 1)Looking for participantsNCT06164730
What this trial is testing

VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease

Who this might be right for
Heterozygous Familial HypercholesterolemiaPremature Coronary Heart Disease
Verve Therapeutics, Inc. 85
Testing effectiveness (Phase 2)Study completedNCT02890992
What this trial is testing

An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Hypercholesterolaemia
Sanofi 42
Not applicableUnknownNCT03393130
What this trial is testing

Perioperative Research Into Memory, Genomics in the Intensive Therapy Unit: Alzheimer's

Who this might be right for
Cognitive ImpairmentApolipoprotein E, Deficiency or Defect ofCritical Illness+2 more
Chelsea and Westminster NHS Foundation Trust 150
Large-scale testing (Phase 3)Study completedNCT00943306
What this trial is testing

Long Term, Follow-on Study of Lomitapide in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
Aegerion Pharmaceuticals, Inc. 19
Early research (Phase 1)Study completedNCT00515307
What this trial is testing

Bone Marrow Stem Cells as a Source of Allogenic Hepatocyte Transplantation in Homozygous Familial Hypercholesterolemia

Who this might be right for
Hypercholesterolemia, Familial
University of Tehran 1
Large-scale testing (Phase 3)Study completedNCT03884452
What this trial is testing

Ezetimibe (SCH 58235) Taken With Either Atorvastatin or Simvastatin in Participants With Familial Hypercholesterolemia (MK-0653-018)

Who this might be right for
Familial Hypercholesterolemia
Organon and Co 50
Large-scale testing (Phase 3)Not Yet RecruitingNCT07473843
What this trial is testing

Study of Zodasiran in Adolescent Participants With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Arrowhead Pharmaceuticals 12
Large-scale testing (Phase 3)Study completedNCT02226198
What this trial is testing

Evaluate the Efficacy and Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
AstraZeneca 20
Not applicableLooking for participantsNCT04815005
What this trial is testing

HoFH, the International Clinical Collaborators Registry

Who this might be right for
Homozygous Familial Hypercholesterolemia
University of Pennsylvania 1,000
Large-scale testing (Phase 3)Study completedNCT03156621
What this trial is testing

Study in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 69
Not applicableLooking for participantsNCT07447648
What this trial is testing

Assessing the Impact of Intensification of Lipid Lowering Therapy With Guidelines-based Evinacumab Administration on Coronary Plaque Volumes Measured by Coronary Computed Tomography Angiography (CCTA) in Patients With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)Coronary Computed Tomography Angiography
Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi) 52
Large-scale testing (Phase 3)Study completedNCT04289285
What this trial is testing

Safety and Efficacy of IBI306 in Chinese Subjects With Non-familial Hypercholesterolemia

Who this might be right for
Hypercholesterolemia
Innovent Biologics (Suzhou) Co. Ltd. 804
Not applicableStudy completedNCT04722068
What this trial is testing

Regeneron 1331 Kinetics Sub-Study HoFH

Who this might be right for
Hypercholesterolemia, Familial
University of Pennsylvania 4
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