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Results for “Familial Hypercholesterolemia With Hyperlipemia”

172 trials

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Showing 20 of 172 results

Testing effectiveness (Phase 2)Study completedNCT02048410
What this trial is testing

Efficacy of a New Symbiotic Formulation in Children With Familial Hypercholesterolemia

Who this might be right for
DyslipidemiaFamilial Hypercholesterolemia
Federico II University 40
Not applicableLooking for participantsNCT06535542
What this trial is testing

Integrating Whole Genome Sequencing and Digital Twins Into the Management of Hypercholesterolemia in Emiratis

Who this might be right for
Hypercholesterolemia, Autosomal DominantHypercholesterolemia, Autosomal RecessiveFamilial Combined Hypercholesterolemia
Abu Dhabi Health Services Company 40
Testing effectiveness (Phase 2)Study completedNCT01576484
What this trial is testing

Open-Label Extension of Study R727-CL-1003 (NCT01266876) to Evaluate the Long-Term Safety and Efficacy of Alirocumab (REGN727) in Participants With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
HypercholesterolemiaHeterozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 58
Not applicableUnknownNCT00924274
What this trial is testing

Effect of Rapeseed Oil and Sunflower Oil

Who this might be right for
Familial Hypercholesterolemia
Medical University of Vienna 24
Large-scale testing (Phase 3)Study completedNCT01623115
What this trial is testing

Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy

Who this might be right for
Hypercholesterolemia
Sanofi 486
Testing effectiveness (Phase 2)Study completedNCT00941603
What this trial is testing

Phase 2 Dose-Ranging Efficacy and Safety Trial of SCH 900271 in Participants With Primary Hypercholesterolemia or Mixed Hyperlipidemia (P05675)

Who this might be right for
Primary HypercholesterolemiaMixed Hyperlipidemia
Merck Sharp & Dohme LLC 619
Large-scale testing (Phase 3)Ended earlyNCT01410383
What this trial is testing

Efficacy and Safety Study of Eprotirome in HeFH Patients Who Are on Optimal Standard of Care

Who this might be right for
Heterozygous Familial Hypercholesterolaemia
Karo Bio AB 236
Large-scale testing (Phase 3)Study completedNCT00136981
What this trial is testing

Carotid B-Mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrpib/Atorvastatin to Atorvastatin Alone.

Who this might be right for
Hypercholesterolemia, FamilialHyperlipidemia
Pfizer 800
Testing effectiveness (Phase 2)Study completedNCT04666298
What this trial is testing

Study of Efficacy and Safety of Inclisiran in Japanese Participants With High Cardiovascular Risk and Elevated LDL-C

Who this might be right for
HypercholesterolemiaHeterozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals 312
Large-scale testing (Phase 3)Study completedNCT03885921
What this trial is testing

Safety and Tolerability Study of Ezetimibe (SCH 058235/MK-0653) Plus Atorvastatin or Simvastatin in Homozygous Familial Hypercholesterolemia (P01417/MK-0653-019)

Who this might be right for
Hypercholesterolemia
Organon and Co 44
Large-scale testing (Phase 3)Study completedNCT02226198
What this trial is testing

Evaluate the Efficacy and Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
AstraZeneca 20
Not applicableLooking for participantsNCT06331195
What this trial is testing

An Adapted Brazilian Cardioprotective Diet, Phytosterols and Krill Oil in Familial Hypercholesterolemia (DICA-FH)

Who this might be right for
Familial Hypercholesterolemia
Hospital do Coracao 300
Testing effectiveness (Phase 2)Study completedNCT02963311
What this trial is testing

ALN-PCSSC in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
The Medicines Company 9
Testing effectiveness (Phase 2)UnknownNCT04455581
What this trial is testing

Determine the Safety, Tolerability, and Efficacy of SHR-1209 in Patients With Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
Jiangsu HengRui Medicine Co., Ltd. 8
Testing effectiveness (Phase 2)Study completedNCT02597127
What this trial is testing

Trial to Evaluate the Effect of ALN-PCSSC Treatment on Low Density Lipoprotein Cholesterol (LDL-C)

Who this might be right for
Atherosclerotic Cardiovascular DiseaseFamilial HypercholesterolemiaDiabetes
The Medicines Company 501
Large-scale testing (Phase 3)Study completedNCT03397121
What this trial is testing

Trial to Evaluate the Effect of Inclisiran Treatment on Low Density Lipoprotein Cholesterol (LDL-C) in Subjects With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial HypercholesterolemiaElevated Cholesterol
The Medicines Company 482
Large-scale testing (Phase 3)Study completedNCT03814187
What this trial is testing

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

Who this might be right for
ASCVDElevated CholesterolHeterozygous Familial Hypercholesterolemia+1 more
Novartis Pharmaceuticals 3,275
Not applicableUnknownNCT03984149
What this trial is testing

Lipa Gene Mutation in PED-LIPIGEN (Pediatric FH Subjects)

Who this might be right for
Lysosomal Acid Lipase Deficiency
Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi) 1,000
Post-approval studies (Phase 4)Study completedNCT05465278
What this trial is testing

Alirocumab and Plaque Burden In Familial Hypercholesterolaemia

Who this might be right for
Familial Hypercholesterolemia
Fundación Hipercolesterolemia Familiar 104
Large-scale testing (Phase 3)Study completedNCT04233918
What this trial is testing

Evaluate the Efficacy and Safety of Evinacumab in Pediatric Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 20
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