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Results for “Familial Hyperchylomicronemia”

28 trials

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Showing 20 of 28 results

Large-scale testing (Phase 3)Study completedNCT05089084
What this trial is testing

Study of ARO-APOC3 (Plozasiran) in Adults With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
Familial Chylomicronemia
Arrowhead Pharmaceuticals 75
Testing effectiveness (Phase 2)Study completedNCT02098278
What this trial is testing

Pilot Study To Assess CAT-2003 in Patients With Chylomicronemia

Who this might be right for
Lipoprotein Lipase Deficiency, FamilialHyperlipoproteinemia Type IChylomicronemia, Familial+1 more
Catabasis Pharmaceuticals 13
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Large-scale testing (Phase 3)Ended earlyNCT01589237
What this trial is testing

Extension to a Randomized, Double-blind, Placebo Controlled Study of LCQ908 in Subjects With Familial Chylomicronemia Syndrome.

Who this might be right for
Familial Chylomicronemia Syndrome (FCS) (HLP Type I)
Novartis Pharmaceuticals 38
Early research (Phase 1)Study completedNCT03783377
What this trial is testing

Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
HypertriglyceridemiaFamilial Chylomicronemia
Arrowhead Pharmaceuticals 112
Not applicableAvailableNCT06796426
What this trial is testing

Treatment Protocol of Plozasiran in Adults With High-Risk Severe Hypertriglyceridemia (SHTG) and in Adults and Adolescents With FCS

Who this might be right for
Familial ChylomicronemiaHigh Risk Severe Hypertriglyceridemia (SHTG)
Arrowhead Pharmaceuticals
Large-scale testing (Phase 3)Looking for participantsNCT07727538
What this trial is testing

Olezarsen for the Treatment of Familial Chylomicronemia Syndrome (FCS) in Pediatric Participants

Who this might be right for
Familial Chylomicronemia Syndrome
Ionis Pharmaceuticals, Inc. 12
Large-scale testing (Phase 3)Study completedNCT05902598
What this trial is testing

ARO-APOC3 / VSA001 / SAR449124 (Plozasiran) in Chinese Adults With Familial Chylomicronemia Syndrome

Who this might be right for
Familial Chylomicronemia Syndrome
Visirna Therapeutics HK Limited 37
Large-scale testing (Phase 3)Study completedNCT00891306
What this trial is testing

Efficacy and Safety of Human Lipoprotein Lipase (LPL)[S447X] Expressed by an Adeno-Associated Viral Vector in LPL-deficient Subjects

Who this might be right for
Familial Lipoprotein Lipase Deficiency
Amsterdam Molecular Therapeutics 5
Large-scale testing (Phase 3)Active Not RecruitingNCT05185843
What this trial is testing

Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults With Familial Chylomicronemia Syndrome (FCS) Previously Treated With Volanesorsen

Who this might be right for
Familial Chylomicronemia Syndrome
Ionis Pharmaceuticals, Inc. 24
Testing effectiveness (Phase 2)Study completedNCT03360747
What this trial is testing

Phase 2 Study of AKCEA-ANGPTL3-LRx (ISIS 703802) in Participants With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
Familial Chylomicronemia SyndromeLipoprotein Lipase DeficiencyHyperlipoproteinemia Type 1
Akcea Therapeutics 3
Large-scale testing (Phase 3)Study completedNCT02658175
What this trial is testing

The Approach Open Label Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Chylomicronemia Syndrome

Who this might be right for
Familial Chylomicronemia SyndromeLipoprotein Lipase DeficiencyHyperlipoproteinemia Type 1
Akcea Therapeutics 68
Not applicableStudy completedNCT04223908
What this trial is testing

InFocus France Epidemiological Study of Health Burden in Major Hypertriglyceridemia

Who this might be right for
Familial Chylomicronemia SyndromeMultifactorial Chylomicronemia Syndrome
New French Society of Atherosclerosis 52
Not applicableApproved For MarketingNCT06360237
What this trial is testing

Olezarsen Early Access Program for Patients With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
Familial Chylomicronemia Syndrome
Ionis Pharmaceuticals, Inc.
Testing effectiveness (Phase 2)Ended earlyNCT01675154
What this trial is testing

Phase 2 Study of Orlistat and SLx-4090 for the Treatment of Type 1 Hyperlipoproteinemia

Who this might be right for
Type 1 Hyperlipoproteinemia
University of Texas Southwestern Medical Center 5
Very early researchLooking for participantsNCT07371767
What this trial is testing

CS-121 APOC3 Base Editing in Children and Adolescents With Hyperchylomicronemia

Who this might be right for
Hyperchylomicronemia
Shanghai Jiao Tong University School of Medicine 15
Large-scale testing (Phase 3)UnknownNCT01109498
What this trial is testing

Safety and Efficacy in LPL-Deficient Subjects of AMT-011, an Adeno-Associated Viral Vector Expressing Human Lipoprotein Lipase [S447X]

Who this might be right for
Familial Lipoprotein Lipase Deficiency
Amsterdam Molecular Therapeutics 14
Large-scale testing (Phase 3)Active Not RecruitingNCT05130450
What this trial is testing

Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Participants With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
Familial Chylomicronemia Syndrome
Ionis Pharmaceuticals, Inc. 60
Not applicableStudy completedNCT03293810
What this trial is testing

Glybera Registry, Lipoprotein Lipase Deficient (LPLD) Patients

Who this might be right for
Lipoprotein Lipase DeficiencyFamilial Hyperlipoproteinemia Type 1Familial Hyperchylomicronemia
UniQure Biopharma B.V. 16
Testing effectiveness (Phase 2)Active Not RecruitingNCT06471543
What this trial is testing

Study of RN0361in Adult Healthy Subjects and Adult Hypertriglyceridemic Subjects

Who this might be right for
HypertriglyceridemiaFamilial Chylomicronemia Syndrome
Ikaria Bioscience Pty Ltd 108
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