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Results for “Familial Hyperchylomicronemia”

27 trials

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Showing 20 of 27 results

Large-scale testing (Phase 3)Study completedNCT02658175
What this trial is testing

The Approach Open Label Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Chylomicronemia Syndrome

Who this might be right for
Familial Chylomicronemia SyndromeLipoprotein Lipase DeficiencyHyperlipoproteinemia Type 1
Akcea Therapeutics 68
Testing effectiveness (Phase 2)Study completedNCT03360747
What this trial is testing

Phase 2 Study of AKCEA-ANGPTL3-LRx (ISIS 703802) in Participants With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
Familial Chylomicronemia SyndromeLipoprotein Lipase DeficiencyHyperlipoproteinemia Type 1
Akcea Therapeutics 3
Testing effectiveness (Phase 2)Study completedNCT01146522
What this trial is testing

Safety, Tolerability,Pharmacokinetics(PK)and Pharmacodynamics(PD)Assessment of LCQ908 in Patients With Severe Hypertriglyceridemia

Who this might be right for
Hyperlipoproteinemia
Novartis Pharmaceuticals 8
Large-scale testing (Phase 3)Study completedNCT00891306
What this trial is testing

Efficacy and Safety of Human Lipoprotein Lipase (LPL)[S447X] Expressed by an Adeno-Associated Viral Vector in LPL-deficient Subjects

Who this might be right for
Familial Lipoprotein Lipase Deficiency
Amsterdam Molecular Therapeutics 5
Not applicableApproved For MarketingNCT06360237
What this trial is testing

Olezarsen Early Access Program for Patients With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
Familial Chylomicronemia Syndrome
Ionis Pharmaceuticals, Inc.
Very early researchLooking for participantsNCT07371767
What this trial is testing

CS-121 APOC3 Base Editing in Children and Adolescents With Hyperchylomicronemia

Who this might be right for
Hyperchylomicronemia
Shanghai Jiao Tong University School of Medicine 15
Not applicableStudy completedNCT03912181
What this trial is testing

Medical Complications in Familial and Multifactorial Chylomicronaemia Syndromes

Who this might be right for
Familial Chylomicronemia SyndromeMultifactorial Chylomicronemia Syndrome
Hospices Civils de Lyon 140
Not applicableAvailableNCT06796426
What this trial is testing

Treatment Protocol of Plozasiran in Adults With High-Risk Severe Hypertriglyceridemia (SHTG) and in Adults and Adolescents With FCS

Who this might be right for
Familial ChylomicronemiaHigh Risk Severe Hypertriglyceridemia (SHTG)
Arrowhead Pharmaceuticals
Large-scale testing (Phase 3)Study completedNCT01514461
What this trial is testing

A Randomized, Double-blind, Placebo Controlled Study to Assess Efficacy, Safety and Tolerability of LCQ908 in Subjects With Familial Chylomicronemia Syndrome

Who this might be right for
Familial Chylomicronemia Syndrome (FCS)
Novartis Pharmaceuticals 45
Not applicableWithdrawnNCT03198897
What this trial is testing

Biomarker for Homozygous Familial Hypercholesterolemia (BioHoFH)

Who this might be right for
Lipoprotein Lipase DeficiencyInborn Error of Lipid MetabolismCorneal Arcus
CENTOGENE GmbH Rostock
Early research (Phase 1)Study completedNCT03783377
What this trial is testing

Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
HypertriglyceridemiaFamilial Chylomicronemia
Arrowhead Pharmaceuticals 112
Not applicableStudy completedNCT04223908
What this trial is testing

InFocus France Epidemiological Study of Health Burden in Major Hypertriglyceridemia

Who this might be right for
Familial Chylomicronemia SyndromeMultifactorial Chylomicronemia Syndrome
New French Society of Atherosclerosis 52
Not applicableNo Longer AvailableNCT03544060
What this trial is testing

Volanesorsen Early Access Program for Patients With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
Familial Chylomicronemia
Akcea Therapeutics
Large-scale testing (Phase 3)Active Not RecruitingNCT05185843
What this trial is testing

Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults With Familial Chylomicronemia Syndrome (FCS) Previously Treated With Volanesorsen

Who this might be right for
Familial Chylomicronemia Syndrome
Ionis Pharmaceuticals, Inc. 24
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Not applicableStudy completedNCT03293810
What this trial is testing

Glybera Registry, Lipoprotein Lipase Deficient (LPLD) Patients

Who this might be right for
Lipoprotein Lipase DeficiencyFamilial Hyperlipoproteinemia Type 1Familial Hyperchylomicronemia
UniQure Biopharma B.V. 16
Very early researchLooking for participantsNCT07176923
What this trial is testing

CS-121 APOC3 Base Editing in FCS

Who this might be right for
Familial Chylomicronemia Syndrome (FCS)
CorrectSequence Therapeutics Co., Ltd 15
Large-scale testing (Phase 3)UnknownNCT01109498
What this trial is testing

Safety and Efficacy in LPL-Deficient Subjects of AMT-011, an Adeno-Associated Viral Vector Expressing Human Lipoprotein Lipase [S447X]

Who this might be right for
Familial Lipoprotein Lipase Deficiency
Amsterdam Molecular Therapeutics 14
Large-scale testing (Phase 3)Study completedNCT02211209
What this trial is testing

The APPROACH Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Patients With Familial Chylomicronemia Syndrome

Who this might be right for
Familial Chylomicronemia Syndrome
Ionis Pharmaceuticals, Inc. 67
Large-scale testing (Phase 3)Study completedNCT05902598
What this trial is testing

ARO-APOC3 / VSA001 / SAR449124 (Plozasiran) in Chinese Adults With Familial Chylomicronemia Syndrome

Who this might be right for
Familial Chylomicronemia Syndrome
Visirna Therapeutics HK Limited 37
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